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  • 1
    Book
    Book
    Moderne Genetik : eine Einführung (1993)
    Heidelberg [u.a.] : Spektrum, Akad. Verl.
    Details Availability
    Keywords: Genetics ; Genetics, Medical ; Molecular Biology ; Lehrbuch Handbuch Standardwerk ; genetics ; Einführung ; Genetik ; Genetik
    Type of Medium: Book
    Pages: XXIII, 493 S. , Ill., graph. Darst.
    ISBN: 3860251805
    Uniform Title: Genetics: a molecular approach 〈dt.〉
    URL: https://swbplus.bsz-bw.de/bsz035772069inh.htm
    RVK:
    VN 8980
    RVK:
    WG 1700
    Language: German
    Note: Literaturangaben
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  • 2
    Online Resource
    Online Resource
    Nutrition and fitness: evolutionary aspects, children's health, programs and policies : 3rd International Conference, Athens, May 1996 (1997)
    Basel [u.a.] : Karger
    Details Availability
    Keywords: Nutritional Physiological Phenomena ; Exercise physiology ; Physical Fitness ; Congresses ; Nutrition ; Sports Medicine ; Dietetics ; Genetics ; Psychology ; Konferenzschrift
    Description / Table of Contents: This is the first of two volumes recording the proceedings of the 3rd International Conference on Nutrition and Fitness. It is the first publication to provide the latest research on the role of exercise and nutrients in gene expression; define the relationship that exists among exercise, nutrition, health and fitness, and examine the scientific evidence from an evolutionary perspective. Stimulating and well-organized, this volume will interest geneticists, anthropologists, exercise physiologists, nutritionists and dietitians, psychologists and psychiatrists, pediatricians, internists, general practitioners, health care providers, industrial scientists, policymakers, and national and international governmental organizations
    Type of Medium: Online Resource
    Pages: Online Ressource (XIV, 172 S.)
    Edition: Online-Ausg. Karger eBooks Collection 1997-2009
    ISBN: 9783318002348
    Series Statement: World review of nutrition and dietetics 81
    URL: http://dx.doi.org/10.1159/isbn.978-3-318-00234-8
    URL: https://karger.com/books/book/2876
    URL: http://www.gbv.de/dms/bowker/toc/9783805564526.pdf
    DOI: 10.1159/isbn.978-3-318-00234-8
    Language: English
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  • 3
    Online Resource
    Online Resource
    The endocrine response to acute illness (1999)
    Basel : Karger
    Details Availability
    Keywords: Homeostasis ; Hormones Metabolism ; Endocrine glands Pathophysiology ; Endocrine manifestations of general diseases ; Endocrine Glands metabolism ; Hormones metabolism ; Acute Disease ; Endocrinology ; Biochemistry ; Biology for Physicians ; Genetics ; Molecular Biology ; Neuroendocrinology
    Description / Table of Contents: Advances in medicine have led to the survival of critically ill patients who would previously have died. The physiological response of patients to critical illness is becoming more clearly defined and this book aims to describe the current state of knowledge of the endocrine aspects of that response. The opening chapter with a careful consideration of carbohydrate metabolism, discusses the changes seen in peripheral glucose uptake and hepatic glucose output in illness. In the next chapter body fluids, solutes, osmolality, the role of the kidneys, thirst and its regulation are considered. Chapter three details work which suggests that there is hypersecretion of parathyroid hormone from an early stage of illness, amongst other topics. Characteristic changes seen in thyroid hormone concentrations during illness and the underlying pathophysiological processes are mentioned in chapter four. With further chapters on the Pituitary Gonadal Axis, The Neuroendocrine Regulation of GH Secretion and GH/IGF-1 as Anabolic Therapy this book provides an overview of the current state of knowledge of endocrine and metabolic function in acute illness. This book will be of interest to physicians, anaesthetists and endocrinologists involved in the care of patients with critical illness
    Type of Medium: Online Resource
    Pages: VIII + 206 S
    Edition: Online-Ausg. Online-Ressource Karger eBooks Collection 1997-2009
    ISBN: 9783318003932 , 0585440972 , 9780585440972
    Series Statement: Frontiers of hormone research 24
    URL: http://dx.doi.org/10.1159/isbn.978-3-318-00393-2
    URL: https://karger.com/books/book/2316
    URL: http://www.gbv.de/dms/bowker/toc/9783805568227.pdf
    DOI: 10.1159/isbn.978-3-318-00393-2
    DDC: 616.4
    Language: English
    Note: Includes bibliographical references and index , ""Contents""; ""Preface""; ""Introduction""; ""Glucose Metabolism""; ""Salt and Water Homeostasis""; ""Calcium Metabolism""; ""Thyroid Hormones""; ""The Pituitary Adrenal Axis""; ""The Pituitary Gonadal Axis""; ""The Regulation of Growth Hormone Secretion""; ""Growth Hormone and IGF-I as Anabolic Therapy""; ""Subject Index""; ""A""; ""B""; ""C""; ""D""; ""E""; ""F""; ""G""; ""H""; ""I""; ""L""; ""M""; ""O""; ""P""; ""R""; ""S""; ""T""; ""U""; ""V""
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  • 4
    Online Resource
    Online Resource
    Genes and genetics of autoimmunity (1999)
    Basel : Karger
    Details Availability
    Keywords: Autoimmunity genetics ; Autoimmune Diseases genetics ; Immunology ; Genetics ; Rheumatology ; Dermatology ; Endocrinology ; Neurology
    Description / Table of Contents: Autoimmunity is one of the most highly investigated areas of immunologic research. The principle of immune system discrimination between self and foreign molecules is fundamental to the survival of the species, and the failure to establish or maintain this discrimination can lead to a wide spectrum of diseases. As a consequence of intensive studies, much has been learned with regard to the normal functioning of the immune system and the editing processes by which self-tolerance is established. Moreover, many theories and experimental models have been developed to explore the mechanisms of autoimmune disease pathogenesis. This book is the first volume of the new series 'Current Directions in Autoimmunity', which aims to consolidate current knowledge of autoimmunity focusing on both basic and clinical aspects. Given that these diseases have a strong genetic basis, it seems appropriate that the first volume addresses this topic. It reviews the most recent findings on genes affecting autoimmunity and genome-wide studies defining the multiple loci predisposing to prominent autoimmune diseases, such as lupus, arthritis, diabetes and multiple sclerosis. For each of these entities, studies in experimental models as well as humans are covered. The authoritative and timely material will be of interest to investigators in the fields of immunology and genetics, to clinicians with interest in rheumatology, endocrinology and neurology, and to those working to devise gene-specific therapies for a variety of inflammatory conditions
    Type of Medium: Online Resource
    Pages: VIII + 296 S
    Edition: Online-Ausg. Online-Ressource Karger eBooks Collection 1997-2009
    ISBN: 9783318003864
    Series Statement: Current directions in autoimmunity 1
    URL: http://dx.doi.org/10.1159/isbn.978-3-318-00386-4
    URL: https://karger.com/books/book/3048
    DOI: 10.1159/isbn.978-3-318-00386-4
    Language: English
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  • 5
    Online Resource
    Online Resource
    Hereditary kidney diseases : Vimercate, September 1996 (1997)
    Basel : Karger
    Details Availability
    Keywords: Kidney Diseases genetics ; Congresses ; Nephrology ; Genetics ; Internal Medicine ; Surgery
    Description / Table of Contents: I would recommend this slim volume for geneticists with an interest in hereditary kidney diseases who would appreciate well written and referenced, up to date papers on the specific conditions included.'Journal of Medical Genetics
    Type of Medium: Online Resource
    Pages: XII + 218 S
    Edition: Online-Ausg. Online-Ressource Karger eBooks Collection 1997-2009
    ISBN: 9783318002515
    Series Statement: Contributions to nephrology 122
    URL: http://dx.doi.org/10.1159/isbn.978-3-318-00251-5
    URL: https://karger.com/books/book/2883
    DOI: 10.1159/isbn.978-3-318-00251-5
    Language: English
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  • 6
    Online Resource
    Online Resource
    Kidney cancer : recent results of basic and clinical research (1999)
    Basel : Karger
    Details Availability
    Keywords: Kidney Neoplasms ; Nephrology ; Genetics ; Oncology ; Pathology
    Description / Table of Contents: Cancer is above all a heritable disorder of somatic cells and gene expression, but environment is also involved in its origin. Hereditary kidney cancer should prove valuable to understand the mechanisms of disease and to the development of therapeutic measures. Recently, scientists have succeeded in cloning and identifying the genes responsible for the following familial kidney cancers: von Hippel-Lindau disease, papillary renal cell carcinoma, tuberous sclerosis and Wilms tumor (all autosomal dominant). This book brings together some of the most recent advances made with respect to kidney cancers: Leading investigators present recent results on VHL, MET, TSC1 and TSC2 and WT1 genes, among others, as well as on environmentally induced kidney cancers (caused by long-term hemodialysis or induced chemically) and their treatments (surgery and gene therapy), providing an excellent survey of this field. This publication will be of interest to both researchers and clinicians concerned with cancer of the kidney
    Type of Medium: Online Resource
    Pages: VIII + 130 S
    Edition: Online-Ausg. Online-Ressource Karger eBooks Collection 1997-2009
    ISBN: 9783318004656
    Series Statement: Contributions to nephrology 128
    URL: http://dx.doi.org/10.1159/isbn.978-3-318-00465-6
    URL: https://karger.com/books/book/2339
    DOI: 10.1159/isbn.978-3-318-00465-6
    Language: English
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  • 7
    Online Resource
    Online Resource
    Animal models of cancer predisposition syndromes : the latest findings by leading investigators (1999)
    Basel : S. Karger
    Details Availability
    Keywords: Cancer Risk factors ; Animal models ; Cancer Genetic aspects ; Animal models ; Neoplasms genetics ; Disease Models, Animal ; Genetic Markers ; Genetic Predisposition to Disease ; Oncology ; Genetics ; Cell Biology ; Molecular Biology ; Krebs ; Prädisposition ; Tiermodell
    Description / Table of Contents: Studies of both spontaneous and environmentally induced tumors have demonstrated that there is considerable variation among individuals in their response to carcinogenesis, suggesting that genetic factors influence the likelihood of developing cancer. The increasing availability of genetic markers has enabled researchers to analyze polygenic traits such as cancer predisposition. Animal models have proved to be useful experimental tools for identifying and characterizing such genetic factors. Such a comparative approach helps to identify factors that animals and man have in common and to elucidate the basic mechanism of determining susceptibility.This book brings together some of the most recent advances made in the genetic analysis of cancer susceptibility using animal models. Leading investigators in the field present model systems for studying cancers including liver and stomach cancer, breast cancer, myeloid leukemia, retrovirus-induced lymphoma, pulmonary adenoma and familial adenomatous polyposis. An overview of transgenic and gene knockout mice is given, and in several chapters the implications of these findings for human cancers are discussed. Providing an excellent survey of the field, the book is recommended reading for all scientists and graduate students in experimental cancer research and cancer genomics
    Type of Medium: Online Resource
    Pages: Online-Ressource
    Edition: Karger eBooks Collection 1997-2009
    ISBN: 3805567197 , 9783805567190 , 9783318003253
    Series Statement: Progress in experimental tumor research 35
    URL: http://dx.doi.org/10.1159/isbn.978-3-318-00325-3
    URL: https://karger.com/books/book/2310
    URL: http://www.gbv.de/dms/bowker/toc/9783805567190.pdf
    DDC: 616.99/4042
    RVK:
    XH 5212
    Language: English
    Note: Includes bibliographical references and indexes , ""Contents""; ""Preface""; ""Multiple Genes Governing Biological Functions in the Genetic Backgrounds of LaboratoryMice and Asian Wild Mice""; ""Overview of Transgenic and Gene Knockout Mice""; ""Alkylation Carcinogenesis in Mice with Altered Levels of DNA Repair Methyltransferase""; ""Cancer Predisposition inMutantMice Defective in the XPC DNA Repair Gene""; ""Myeloid Leukemia: Disease Genes and MouseModels""; ""Genetic and Epigenetic Susceptibility to Endogenous Retrovirus-Induced Lymphomas in SL Mice""; ""Inheritance of Pulmonary Adenoma Susceptibility in Mice"" , ""TSC2 GeneMutant (Eker) Rat Model of a Mendelian Dominantly Inherited Cancer""""Apc Gene KnockoutMice as a Model for Familial Adenomatous Polyposis""; ""A Rat Model System for Predisposition to Stomach Cancer""; ""Genetic and Hormonal Regulation of Murine Hepatocarcinogenesis""; ""Genetics of Skin Tumor Promotion""; ""The Genetic Components of Susceptibility to Breast Cancer in the Rat""; ""Author Index""
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  • 8
    Online Resource
    Online Resource
    Nutrition and fitness: Metabolic and Behavioral Aspects in Health and Disease : 3rd International Conference on Nutrition and Fitness, Athens, May 1996 (1997)
    Basel : S. Karger
    Details Availability
    Keywords: Nutrition ; Dietetics ; Genetics ; Psychology ; Sports Medicine
    Description / Table of Contents: This is the second of two volumes recording the proceedings of the 3rd International Conference on Nutrition and Fitness. The papers in this volume provide scientific information on the interrelationship of diet and physical activity in health and disease from the metabolic and behavioral standpoint. Stimulating and well-organized, this volume will interest geneticists, anthropologists, exercise physiologists, nutritionists and dietitians, psychologists and psychiatrists, pediatricians, internists, general practitioners, health care providers, industrial scientists, policymakers, and national and international governmental organizations
    Type of Medium: Online Resource
    Pages: XIV + 266 S
    Edition: Online-Ausg.] Online-Ressource Karger eBooks Collection 1997-2009
    ISBN: 9783318002379
    Series Statement: World review of nutrition and fitness 82
    URL: https://karger.com/books/book/2878
    Language: English
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  • 9
    Online Resource
    Online Resource
    Genetic variation and dietary response : [... papers presented at the International Conference on 'Genetic Variation and Nutrition' held in June 1989 in Washington, DC] ; 4 tables (1997)
    Basel : Karger
    Details Availability
    Keywords: Chronic diseases Nutritional aspects ; Chronic diseases Genetic aspects ; Lipids Metabolism ; Genetic aspects ; Lipids Metabolism ; Disorders ; Genetic aspects ; Nutrition disorders Genetic aspects ; Genetic Predisposition to Disease ; Genetic Variation ; Chronic Disease ; Diet Therapy ; Diet adverse effects ; Nutrition ; Genetics ; Cardiovascular System ; Dietetics ; Metabolism ; Public Health ; Chronische Krankheit ; Erbkrankheit ; Ernährung
    Description / Table of Contents: This timely volume focuses on genetics and nutrition, and their interaction in the development of chronic diseases. Knowledge of genetic susceptibility to disease will not only help to identify those at higher risk for disease but also to ascertain their response to diet. The prospect of targeting specific dietary treatment at those predicted to gain the most therapeutic benefit clearly has important clinical and economic consequences, particularly in diseases of high prevalence. This book is unique in considering genetic variation in susceptibility to disease, and the importance of specific diets in influencing lipid levels in cardiovascular disease and bone density in osteoporosis. The contributions emphasize that dietary response is dependent on the genetic variant and that specific dietary recommendations rather than universal ones are needed for the prevention and management of chronic diseases. Bringing together vital information for the first time, this book is important reading for physicians, nutritionists, dietitians, geneticists, physiologists, molecular biologists, food technologists and policymakers
    Type of Medium: Online Resource
    Pages: Online-Ressource
    Edition: Karger eBooks Collection 1997-2009
    ISBN: 9783318002133
    Series Statement: World review of nutrition and dietetics 80
    URL: http://dx.doi.org/10.1159/isbn.978-3-318-00213-3
    URL: https://karger.com/books/book/2868
    URL: http://www.gbv.de/dms/bowker/toc/9783805563475.pdf
    DDC: 612.3 s
    RVK:
    YC 6219
    Language: English
    Note: Based on papers presented at the International Conference on Genetic Variation and Nutrition, held in June 1989 in Washington, DC , Includes bibliographical references and indexes
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  • 10
    Online Resource
    Online Resource
    Molecular pathology of diabetes mellitus (1997)
    Basel : S. Karger
    Details Availability
    Keywords: Diabetes Mellitus, Insulin-Dependent etiology ; Diabetes Mellitus, Non-Insulin-Dependent etiology ; Endocrinology ; Molecular Biology ; Diabetes ; Genetics ; Immunology ; Metabolism ; Aufsatzsammlung ; Diabetes mellitus ; Pathogenese ; Molekularbiologie
    Description / Table of Contents: Diabetes, already a prevalent disease worldwide, is increasing at a rate consistent with a global epidemic. The number of people affected is expected to double in the next 15 years to about 200 million. The disease is already one of the commonest causes of kidney failure, blindness and amputations. There is an urgent need to prevent either the development of these complications or the disease itself. Dramatic advances in our understanding of the pathogenesis of diabetes have led to the hope that diabetes can indeed be prevented. Several major international collaborative projects have been initiated with this aim. In this book, an outstanding group of international scientists provide a broad outline of the advances in basic science which underpin these projects. The book offers a clear, comprehensive and up-to-date account for the interested clinician and scientist, and will be invaluable as a reference book for those working in the field.
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource (VIII, 228 Seiten)
    ISBN: 9783318036688
    Series Statement: Frontiers of hormone research 22
    URL: https://karger.com/books/book/2267
    URL: http://www.gbv.de/dms/bowker/toc/9783805563734.pdf
    DDC: 616.4/62071
    Language: English
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