Note: Intro -- Umweltanalytik mit Spektrometrie und Chromatographie -- Vorwort zur 3. Auflage -- Inhaltsverzeichnis -- 1 Einleitung -- 2 Laborgestaltung -- 3 Managementstrategien für Umweltlabore -- 3.1 Selbstmanagement -- 3.2 Teammanagement -- 3.3 Labormanagement -- 3.3.1 Zertifizierung -- 3.3.2 Akkreditierung -- 3.3.3 Grundsätze der Guten Laborpraxis (GLP) -- 3.4 Beziehungsmanagement -- 3.4.1 Der König Kunde -- 3.4.2 Staatliche Institutionen -- 3.4.3 Auditoren -- 3.4.4 Kundendienst -- 3.4.5 Zulieferer -- 3.5 Zukunftsaspekte -- 4 Umweltgesetzgebung -- 4.1 Trink- und Brauchwasser -- 4.1.1 E.U. Richtlinien -- 4.1.2 Nationale Gesetze, Empfehlungen, Beurteilungskriterien -- 4.2 Mineral- und Tafelwasser -- 4.2.1 E.U. Richtlinien -- 4.2.2 Nationale Gesetze, Empfehlungen, Beurteilungskriterien -- 4.3 Badewasser -- 4.3.1 E.U. Richtlinien -- 4.3.2 Nationale Gesetze, Empfehlungen, Beurteilungskriterien -- 4.4 Oberirdische Gewässer -- 4.4.1 E.U. Richtlinien -- 4.5 Abwasser -- 4.5.1 E.U. Richtlinien -- 4.5.2 Nationale Gesetze, Empfehlungen, Beurteilungskriterien -- 4.6 Sickerwasser und Grundwasser -- 4.6.1 E.U Richtlinien -- 4.6.2 Nationale Gesetze, Empfehlungen, Beurteilungskriterien -- 4.7 Nutz- und Kulturböden -- 4.7.1 E.U. Richtlinien -- 4.7.2 Nationale Gesetze, Empfehlungen, Beurteilungskriterien -- 4.8 Altlasten -- 4.8.1 Nationale Gesetze, Empfehlungen, Beurteilungskriterien -- 4.9 Klärschlamm -- 4.9.1 E.U. Richtlinien -- 4.9.2 Nationale Gesetze, Empfehlungen, Beurteilungskriterien -- 4.10 Abfall -- 4.10.1 E.U. Richtlinien -- 4.10.2 Nationale Gesetze, Empfehlungen, Beurteilungskriterien -- 4.11 Gefahrstoffe -- 4.11.1 E.U. Richtlinien -- 4.11.2 Nationale Gesetze, Empfehlungen, Beurteilungskriterien, usw. -- 4.12 Immissionsschutz -- 4.12.1 E.U.-Richtlinien -- 4.12.2 Nationale Gesetze, Empfehlungen, Beurteilungskriterien, usw. , 4.13 Bezugsquellen von Gesetzen, Verordnungen, Richtlinien, usw. -- 4.14 Bezugsquellen für Bundesländer spezifische Umweltgesetze -- 4.15 Bezugsquellen von nationalen und internationalen Analysenverfahren -- 5 Untersuchungsstrategie -- 5.1 Gesetzliche Vorgaben -- 5.2 Von der Analysenstrategie bis zur Interpretation und Dokumentation von Analysendaten -- 5.3 Auswahlkriterien für Analysenverfahren -- 5.3.1 Vorgaben für das Analysenverfahren aus der Umweltgesetzgebung -- 5.3.2 Auswahl des geeigneten Analysengerätes -- 5.3.3 Analytische Sicherheit -- 5.3.4 Wirtschaftlichkeitsbetrachtungen -- 6 Probenahme -- 6.1 Probenahme von Gasen -- 6.1.1 Probenahme mittels einer Gasmaus -- 6.1.2 Probenahme durch Sammeln von Aerosolen und Staubpartikeln auf Filtern -- 6.1.3 Probenahme durch Absorption der zu analysierenden Stoffe in Flüssigkeiten -- 6.1.4 Probenahme durch Adsorption der zu bestimmenden Komponenten an Adsorptionsmaterialien -- 6.2 Probenahme von Flüssigkeiten -- 6.3 Probenahme von Feststoffen -- 6.3.1 Probenahme von Böden -- 6.3.2 Probenahme von Schlämmen -- 6.3.3 Probenahme von Sedimenten -- 6.3.4 Probenahme von Abfällen und Müll -- 6.3.5 Probenahme von Altlasten-Verdachtsflächen -- 7 Konservierung und Lagerung von Umweltproben -- 8 Probenvorbereitung -- 8.1 Physikalische Probenvorbereitungstechniken -- 8.1.1 Bestimmung des Trockenrückstandes nach DIN 38414-2 (DEV-S 2) bei 105C -- 8.1.2 Bestimmung und Herstellung der Trockenmasse durch Gefriertrocknung -- 8.1.3 Trocknung von Bodenproben an der Luft -- 8.1.4 Zerkleinern und Sieben -- 8.2 Lösungen, Eluate und Aufschlüsse -- 8.2.1 Lösungen -- 8.2.2 Eluate -- 8.2.3 Aufschlüsse -- 8.3 Abtrennungs- und Anreicherungsverfahren -- 8.3.1 Adsorption und Absorption von gasförmigen Proben -- 8.3.2 Purge- und Trapverfahren -- 8.3.3 Dampfraumanalyse -- 8.3.4 Flüssig-Flüssig-Extraktion -- 8.3.5 Festphasenextraktion. , 8.3.6 Soxhlet-Extraktion -- 8.3.7 Extraktion mit überkritischen Gasen -- 8.4 Clean-up-Verfahren -- 9 Vor-Ort-Analytik -- 9.1 Sensorbasierte Messmethoden -- 9.2 Nicht sensorbasierte Messmethoden -- 9.2.1 UV/VIS-Spektrometrie (UV/VIS) -- 9.2.2 Infrarot-Spektrometrie (IR) -- 9.2.3 Atomabsorptions-Spektrometrie (AAS) -- 9.2.4 ICP-Atomemissions-Spektrometrie (ICP-AES) -- 9.2.5 ICP-Massenspektrometrie (ICP-MS) -- 9.2.6 Gaschromatographie (GC) und GC-Massenspektrometrie (GC-MS) -- 9.2.7 Hochleistungs-Flüssigkeits-Chromatographie (HPLC) -- 9.2.8 Kapillarelektrophorese (CE) -- 10 Instrumentelle Analysenverfahren -- 10.1 Spektrometrie -- 10.1.1 UV/VIS-Spektrometrie (UV/VIS) -- 10.1.2 Fluoreszenz-Spektrometrie (FLUO) -- 10.1.3 Infrarot-Spektrometrie (IR) -- 10.1.4 Atomabsorptions-Spektrometrie (AAS) -- 10.1.5 ICP-Atomemissions-Spektrometrie (ICP-AES) -- 10.1.6 ICP-Massenspektrometrie (ICP-MS) -- 10.1.7 Atomfluoreszenz-Spektrometrie (AFL) -- 10.2 Chromatographie -- 10.2.1 Gaschromatographie (GC) -- 10.2.2 Hochleistungs-Flüssigkeits-Chromatographie -- 10.2.3 Dünnschicht-Chromatographie (DC) -- 10.3 Kapillarelektrophorese (CE) -- 11 Analytische Qualitätssicherung (AQS) -- 11.1 AQS-Systeme im Überblick -- 11.1.1 Zertifizierung auf der Basis von DIN EN ISO 9000 ff -- 11.1.2 Akkreditierung nach DIN EN ISO 17025 -- 11.1.3 Grundsätze der Guten Laborpraxis (GLP) -- 11.1.4 Notifizierung für die Fachmodule Umweltanalytik durch die Bundesländer -- 11.2 Einführung eines AQS-Systems -- 11.2.1 Akkreditierung nach DIN EN ISO 17025 -- 11.2.2 Notifizierung für entsprechende Fachmodule -- 11.3 AQS-Maßnahmen in der Laborpraxis -- 12 Labordatenverwaltung -- 13 Interpretation und Dokumentation von Analysendaten -- Sachregister.

Note: Cover -- Contents -- List of Contributors -- Preface -- Introduction -- Chemopreventive Compounds in the Diet -- Abstract -- Vitamin C -- Food Sources -- Function -- Deficiency -- Disease Prevention -- Cardiovascular Diseases -- Cancer -- Cataracts -- Safety -- Vitamin E -- Food Sources -- Function -- alpha-Tocopherol -- gama-Tocopherol -- Deficiency -- Disease Prevention -- Cardiovascular Diseases -- Cancer -- Cataracts -- Immune Function -- Safety -- Copper -- Food Sources -- Function -- Nutrient-Nutrient Interactions -- Deficiency -- Individuals at Risk of Deficiency -- Disease Prevention -- Cardiovascular Diseases -- Osteoporosis -- Immune Function -- Safety -- Selenium -- Food Sources -- Function -- Nutrient-Nutrient Interactions -- Deficiency -- Individuals at Risk of Deficiency -- Disease Prevention -- Cardiovascular Diseases -- Cancer -- Immune Function -- Viral Infection -- Safety -- Zinc -- Food Sources -- Function -- Nutrient-Nutrient Interactions -- Deficiency -- Disease Prevention -- Growth and Development -- Immune Function -- Pregnancy Complications -- Age-Related Macular Degeneration -- Safety -- Carotenoids: alpha-Carotene, beta-Carotene, beta-Cryptoxanthin, Lycopene, Lutein and Zeaxanthin -- Food Sources -- Function -- Deficiency -- Disease Prevention -- Cardiovascular Diseases -- Age-Related Macular Degeneration -- Cataracts -- Cancer -- Bioavailability of Carotenoids -- Safety -- Interactions among Drugs and Carotenoids -- Polyphenols and Flavonoids -- Food Sources -- Function -- Disease Prevention -- Antioxidant Properties and Enzyme Inhibition -- Anti-Inflammatory Activity -- Vascular Activity -- Coronary Heart Disease -- Cytotoxic Antitumor Activity -- Estrogenic Activity -- Other Biological Activities -- Safety -- alpha-Lipoic Acid -- Food Sources -- Function -- Deficiency -- Disease Prevention -- Diabetes mellitus. , Safety -- Acknowledgement -- References -- Biochemistry -- Vitamin C, Vitamin E and Flavonoids -- Abstract -- Reactive Oxygen Species and the Eye -- Ascorbic Acid (Vitamin C) -- Tocopherols (Vitamin E) -- Flavonoids -- Synergistic Effects -- Conclusion -- References -- Macular Carotenoids: Lutein and Zeaxanthin -- Abstract -- Structure and Biosynthesis -- Occurrence in Food -- Absorption, Distribution and Metabolism -- The Macular Pigment -- Oxidative Stress -- Photooxidative Stress -- Carotenoids as Antioxidants -- Carotenoids as Blue Light Filters -- Conclusion -- References -- Selenium, Selenoproteins and Vision -- Abstract -- Unspecific Selenium Effects versus Enzymatic Selenium Catalysis -- Selenoproteins of the Eye -- Glutathione Peroxidases and Experimental Cataracts -- Animal Experiments versus Clinical Experience -- Conclusions -- References -- Clinics -- Nutritional Supplementation to Prevent Cataract Formation -- Abstract -- Cataract Development -- Therapeutics -- Vitamin C -- Vitamin E -- Carotenoids -- Epidemiological Studies -- Clinical Interventional Studies -- 'Linxian' Studies -- The AREDS Trial -- The REACT Study -- The PHS Studies -- The ATBC Study -- The VECAT Study -- Conclusion -- References -- Nutrition and Retina -- Abstract -- Age-Related Macular Degeneration -- Nutrition and Pathomechanisms in AMD -- Oxidative Stress Theory -- Choroidal Circulation Theory -- Bruch's Membrane Theory -- Dietary Components with a Possible Role in Retinal Degeneration -- Antioxidants -- Vitamin E -- Vitamin C -- Carotenoids -- beta-Carotene -- Lutein and Zeaxanthin -- Cofactors of Antioxidant Enzymes -- Folic Acid -- Nutritional Risk Factors -- Dietary Fat Intake -- Smoking -- Alcohol -- The Age-Related Eye Disease Study -- Conclusion -- Diabetic Retinopathy/Maculopathy -- Conclusion -- References -- Author Index -- Subject Index -- A -- B -- C. , D -- F -- G -- I -- K -- L -- M -- N -- O -- P -- R -- S -- T -- V -- Z.

Note: NITRITE CURING OF MEAT -- CONTENTS -- 1 . INTRODUCTION -- 2 . HISTORY OF THE CURING PROCESS -- 3 . THE COLOR OF MEAT -- 4 . OXIDATIVE STABILITY OF MEAT LIPIDS -- 5 . FLAVOR OF MEAT -- 6 . MEAT MICROBIOLOGY -- 7 . THE FATE OF NITRITE -- 8 . POTENTIAL HEALTH CONCERNS ABOUT NITRITE -- 9 . POSSIBLE SUBSTITUTES FOR NITRITE -- GLOSSARY -- INDEX.

Note: Cover -- Handbook of Pediatric Transfusion Medicine -- Copyright -- Dedication -- Table of Contents -- Preface -- Acknowledgments -- About the Editors -- List of Contributors -- Chapter 1 Blood Donation -- Overview -- Donor Recruitment -- Autologous Donation -- Directed Donation -- Limited Donor Exposure -- Blood Collection -- Apheresis -- Plasmapheresis -- References -- Chapter 2 Component Preparation and Storage -- Introduction -- Unique Transfusion Needs of the Neonatal and Pediatric Patient -- Blood Donation Issues -- Anticoagulant-Preservative Solutions -- Individual Components for Transfusion -- Record Keeping for Component Preparation -- Storage of Blood and Blood Products -- Summary -- References -- Chapter 3 Blood Components -- Introduction -- Whole Blood and Packed Red Blood Cells -- Platelets -- Granulocytes -- Plasma Products -- Cryoprecipitate -- Ordering -- Coagulation Factors -- Albumin -- Gamma-Globulins -- References -- Chapter 4 Red Blood Cell Antigens and Human Blood Groups -- Introduction -- ABO Blood Group System -- RH Blood Group System -- Kell Blood Group System -- Duffy Blood Group System -- Clinical Significance -- Kidd Blood Group System -- MNS Blood Group System -- P Blood Group System -- Lutheran Blood Group System -- Lewis Blood Group System -- Diego Blood Group System -- Cartwright Blood Group System -- Xg Blood Group System -- Scianna Blood Group System -- Dombrock Blood Group System -- Colton Blood Group -- LW Blood Group System -- Chido-Rogers Blood Group System -- Hh Blood Group System -- XK Blood Group System -- Gerbich Blood Group System -- Cromer Blood Group System -- Knops Blood Group System -- Indian Blood Group System -- Ok Blood Group System -- RAPH Blood Group System -- JMH Blood Group System -- Cost Blood Group Collection -- Er Blood Group Collection -- Ii Blood Group Collection -- Globoside Collection. , Low-Prevalence Antigens -- High-Prevalence Antigens -- References -- Chapter 5 Pretransfusion Compatibility Testing -- Introduction -- ABO(H) -- Rh(D) -- Other Red Cell Antigens -- Direct Antiglobulin Test -- Antibody Detection Test (Screen) -- Crossmatch (XM) -- Turnaround Times -- Suggested Reading -- References -- Chapter 6 Serologic Investigation of Unexpected Antibodies -- Introduction -- Common Antibody Identification Methods -- Process for Evaluation of Positive Antibody Detection Tests -- References -- Chapter 7 Leukoreduced Products: Prevention of Leukocyte-Related Transfusion-Associated Adverse Effects -- Introduction -- Rationale for Leukoreduction of Blood Components -- Specific Indications for LR Products -- Contraindications, Side Effects, and Hazards -- Leukoreduction Technologies -- Products, Standards, and Quality Control -- Universal Leukoreduction -- Leukoreduced Blood Products and Pediatric Transfusion Medicine -- References -- Chapter 8 Preparation of Blood Components to Reduce Cytomegalovirus and Other Infectious Risks -- Introduction -- Red Blood Cell and Platelet Components with Reduced Infectious Risks -- Plasma Components, Derivatives, and Factors to Eliminate Pathogens -- Nucleic Acid Targeted Inactivation Strategies -- Summary -- References -- Chapter 9 Irradiated Products -- History -- Pathogenesis -- Clinical Manifestations -- Diagnosis of TA-GVHD -- Time Course of Microchimerism -- Groups at Risk -- The Irradiation Process -- Instrumentation for Irradiation -- Components to be Irradiated -- Storage of Red Cells and Platelets after Irradiation -- Selection of Radiation Dose -- Quality Assurance Measures -- Confrming That Irradiation Occurred -- New Methods in the Prevention of TA-GVHD -- Treatment of TA-GVHD -- References -- Chapter 10 Washed and/or Volume- Reduced Blood Components -- Introduction. , Washed Red Blood Cells -- Washed And Volume-Reduced Platelet Concentrates -- References -- Chapter 11 Technical Considerations/Mechanical Devices -- Introduction -- Intravenous Delivery Systems for Blood and Components -- Exchange Transfusion in the Newborn -- References -- Chapter 12 Red Blood Cell Transfusions in the Neonate, Infant, Child, and Adolescent -- Introduction -- RBC Transfusions for Children and Adolescents -- RBC Transfusions for Neonates and Infants -- References -- Chapter 13 Transfusion of the Pediatric Surgery, Trauma, and Intensive Care Unit Patient -- Abstract -- Age, Size, and Rate of Transfusion -- Red Blood Cell Transfusion -- Platelet Transfusions -- Cryoprecipitate and Fresh Frozen Plasma -- Hemostatic Agents in Acute Care -- References -- Chapter 14 Pediatric Transfusion in Developing Countries -- Introduction -- Special Transfusion Issues in Resource-Restricted Countries -- Blood Collection and Processing in Developing Countries -- Risks of Infectious Disease Transmission by Transfusion -- Current Transfusion Practices -- Prevention Measures to Reduce Need for Transfusion -- References -- Chapter 15 Exchange Transfusion in the Infant -- Introduction -- Rationale and Indications -- Procedure -- Selection of Donor Blood -- Complications -- References -- Chapter 16 Granulocyte Transfusions in the Neonate and Child -- Abstract -- Introduction -- Myelopoiesis -- Neonatal Neutropenia and Dysfunction -- Childhood Neutropenia -- Mobilization of Donor Granulocytes -- Therapeutic Granulocyte Transfusions in Children and Adults -- Granulocyte Transfusion in the Neonate -- Summary and Recommendations of Granulocyte Transfusions -- References -- Chapter 17 Extracorporeal Membrane Oxygenation and Cardiopulmonary Bypass -- Introduction -- Circuit for ECMO and CPB -- ECMO -- CPB -- Summary -- References. , Chapter 18 Hemolytic Disease of the Newborn -- Introduction -- Immune-Mediated Hemolytic Disease -- Rh Hemolytic Disease -- ABO Hemolytic Disease -- Hemolytic Disease Due to Other Red Cell Antibodies -- T Activation -- Autoimmune Hemolytic Disease -- Red Cell Enzyme Deficiencies -- Red Cell Membrane Defects -- Disorders of Hemoglobin Synthesis -- Other Causes of Hemolytic Disease in Neonates -- Therapy -- References -- Chapter 19 Hemoglobinopathies -- Introduction -- Sickle Cell Disease -- Thalassemias -- References -- Chapter 20 The Bleeding Child: Congenital and Acquired Disorders -- Abstract -- Introduction -- Coagulation Overview -- Clinical Evaluation of Bleeding Problems -- Laboratory Evaluation -- Specific Factor Assays -- Inherited Coagulation Disorders -- Acquired Hemorrhagic Disorders -- References -- Chapter 21 Transfusion of the Patient with Autoimmune Hemolysis -- Introduction -- Clinical Presentation and Laboratory Findings -- Classification -- Warm Autoimmune Hemolytic Anemia -- Cold Agglutinin Syndrome -- Mixed-Type Autoimmune Hemolytic Anemia -- Drug-Induced Hemolytic Anemia -- Less Common Types of Autoimmune Hemolytic Anemia -- Transfusion Therapy in Autoimmune Hemolytic Anemia -- References -- Chapter 22 Platelet Transfusions in the Infant and Child -- Introduction -- Platelet Products and Special Preparations -- Platelet Transfusions in Children -- Platelet Transfusions in Neonates -- Reactions to Platelet Transfusions -- Potential Alternatives to Platelet Transfusions -- References -- Chapter 23 Bone Marrow-Derived Stem Cells -- Introduction -- Product Description -- Collection and Storage -- Special Preparation and Processing -- Expected Response -- Alternative HPC Sources -- References -- Chapter 24 Peripheral Blood Stem Cells -- Introduction -- Product Description -- Collection -- Special Preparation. , Ordering and Administration -- Potential Adverse Effects -- Alternative HPC Sources -- References -- Chapter 25 Umbilical Cord Blood Stem Cells -- Introduction -- Collection, Storage, and Handling -- Clinical Applications -- References -- Chapter 26 Transfusion Reactions -- Introduction -- Acute Hemolytic Transfusion Reactions -- Febrile Nonhemolytic Transfusion Reactions -- Allergic Transfusion Reactions -- Delayed Hemolytic Transfusion Reactions -- Special Considerations for Newborn Infants -- References -- Chapter 27 Noninfectious Complications of Pediatric Transfusion -- Introduction -- Transfusion Reactions -- Metabolic Complications -- Cardiac Overload -- Alloimmunization -- T Antigen Activation -- Dilutional Coagulopathy -- Complications of Iron Overload from Chronic Transfusion -- References -- Chapter 28 Infectious Complications -- Introduction -- Human Immunodeficiency Virus -- Hepatitis -- Human T-Cell Lymphotropic Virus (HTLV) -- Cytomegalovirus -- Parvovirus B19 -- Parasitic Infections -- Creutzfeldt-Jakob Disease -- Bacterial Infections -- References -- Chapter 29 Therapeutic Apheresis -- Introduction -- Goals of Therapeutic Apheresis -- Indication Categories -- Physiology and Adverse Effects -- General Approach to Pediatric Patients Needing Therapeutic Apheresis -- Planning Pediatric Procedures -- Vascular Access -- Hemodynamic Challenges -- Procedural Modifications for Pediatric Patients -- Summary -- Suggested Reading -- Chapter 30 Therapeutic Cytapheresis -- Introduction -- Evidence-Based Practice Guidelines -- General Technical Considerations for Pediatrics -- Erythrocytapheresis/Red Cell Exchange Transfusion -- Leukapheresis -- Plateletpheresis (Thrombocytapheresis) -- Adverse Reactions -- References -- Chapter 31 Therapeutic Plasma Exchange: Rationales and Indications -- Introduction -- Guillain-Barré Syndrome. , Chronic Inflammatory Demyelinating Polyneuropathy.

Note: Front Cover -- Inside Cover -- Copyright ©2005 Eurekah.com -- CONTENTS -- CONTRIBUTORS -- PREFACE -- ABBREVIATIONS -- Acknowledgements -- CHAPTER 1 Normal Hematopoietic Cell Differentiation -- CHAPTER 2 Application of Monoclonal Antibodies to the Diagnosis and Classification of Acute Leukemias -- CHAPTER 3 Immunophenotypic Markers in the Diagnosis of Non-Hodgkin's Lymphomas -- CHAPTER 4 Clinical Application of Immunophenotyping in Immunodeficiencies -- CHAPTER 5 Immunophenotyping in Hematopoietic Stem Cell Transplantation -- INDEX -- Back Cover.

Note: Intro -- Areas of Specialization Abbreviations -- Afghanistan -- Angola -- Antigua and Barbuda -- Argentina -- Armenia -- Australia -- Azerbaijan -- Bahamas -- Bahrain -- Bangladesh -- Barbados -- Belize -- Benin -- Bermuda -- Bolivia -- Botswana -- Brazil -- British Virgin Islands -- Burkina Faso -- Cambodia -- Cameroon -- Canada -- Cayman Islands -- Chile -- China, People's Republic -- China, Republic -- Colombia -- Costa Rica -- Côte d'lvoire -- Cuba -- Dominica -- Dominican Republic -- East Timor -- Ecuador -- Egypt -- El Salvador -- Eritrea -- Ethiopia -- Fiji -- Gambia -- Georgia -- Ghana -- Grenada -- Guam -- Guatemala -- Haiti -- Honduras -- India -- Indonesia -- Iran -- Iraq -- Israel -- Jamaica -- Japan -- Jordan -- Kazakhstan -- Kenya -- Kiribati -- Korea, Republic -- Kuwait -- Kyrgyzstan -- Lebanon -- Libya -- Malawi -- Malaysia -- Mexico -- Mongolia -- Morocco -- Namibia -- Nepal -- Netherlands Antilles -- New Zealand -- Nicaragua -- Niger -- Nigeria -- Pakistan -- Panama -- Paraguay -- Peru -- Philippines -- Rwanda -- St. Kitts-Nevis -- St. Lucia -- St. Vincent and the Grenadines -- Samoa -- Saudi Arabia -- Senegal -- Sierra Leone -- Singapore -- South Africa -- Sri Lanka -- Suriname -- Swaziland -- Tajikistan -- Tanzania -- Thailand -- Tunisia -- Turkmenistan -- Uganda -- United Arab Emirates -- Uruguay -- U.S.A -- Uzbekistan -- Vanuatu -- Venezuela -- Vietnam -- Zambia -- Zimbabwe -- INDEX -- Alphabetical Index to Foundation Names -- Subject Index.

Note: Cover -- Contents -- List of Illustrations -- Preface -- 1. The Nuclear Power Debate -- 2. The Regulation of Nuclear Power -- 3. Defense in Depth -- 4. Wednesday, March 28: "This Is the Biggie" -- 5. Thursday, March 29: "The Danger Is Over for People Off Site" -- 6. Friday, March 30: "Going to Hell in a Handbasket" -- 7. Saturday, March 31: "You're Causing a Panic!" -- 8. Sunday, April 1: "Look What We Have Done to These Fine People" -- 9. The Immediate Aftermath of the Accident -- 10. The Long-Term Effects of Three Mile Island -- Notes -- Essay on Sources -- Index -- A -- B -- C -- D -- E -- F -- G -- H -- I -- J -- K -- L -- M -- N -- O -- P -- Q -- R -- S -- T -- U -- V -- W -- X -- Y -- Z.

Note: Intro -- Macromolecules Containing Metal and Metal-Like Elements Volume 3 -- Contributors -- Contents -- Preface -- Series Preface -- 1. Organometallic Compounds in Biomedical Applications -- I. Introduction -- II. Case for Metal-Containing Bioactive Agents -- A. Tin-Containing Biocidal Polymers -- B. Ferrocene: A Therapeutic Role in Polymeric Systems? -- C. Polymeric Moderation of OsO(4) Toxicity -- III. Miscellaneous Polymers -- A. Metal Chelation Polymers -- B. Condensation Polymers -- IV. Small-Molecule Analogs -- V. Summary -- VI. References -- 2. Metal-Labeled DNA on Surfaces -- I. Introduction -- II. Ferrocene Nucleotides -- III. Ferrocene-DNA Conjugates -- IV. Other Metal-DNA Conjugates -- V. Metallated DNA -- A. Cu-DNA -- B. M-DNA -- VI. Summary -- VII. Acknowledgments -- VIII. References -- 3. Artificial DNA through Metal-Mediated Base Pairing: Structural Control and Discrete Metal Assembly -- I. Introduction -- II. Alternative Hydrogen-Bonding Schemes for DNA Base Pairing -- III. Non-Hydrogen-Bonding Basepairs in DNA -- IV. Metal-Mediated Base Pairing in DNA -- A. Basic Concept -- B. Artificial Nucleosides Designed for Metal-Mediated Base Pairs -- C. Incorporation of a Metallo-Base Pair in DNA and Its Effect on Thermal Stability -- D. Discrete Self-Assembled Metal Arrays in DNA -- V. Future Prospects for Artificial Metallo-DNA -- VI. Summary -- VII. References -- 4. Organotin Macromolecules as Anticancer Drugs -- I. General -- II. Anticancer Activity of Small Organotin Compounds -- III. Molecule-Level Studies on Monomeric Organotin Compounds -- IV. Anticancer Activity of Organotin Polymers -- V. Future Work -- VI. References -- 5. Organotin Oligomeric Drugs Containing the Antivirial Agent Acyclovir -- I. Early History of Organotin Compounds -- II. Mechanisms and Reactions -- III. General Structures -- IV. Acyclovir. , V. Bioactivity of Related Compounds -- VI. Experimental Work -- VII. Results and Discussion -- VIII. References -- 6. Polymeric Ferrocene Conjugates as Antiproliferative Agents -- I. Introduction -- II. The Ferrocene-Ferricenium System in the Biological Environment -- III. Polymer-Drug Conjugation as a Pharmaceutical Tool for Drug Delivery -- IV. Polymer-Ferrocene Conjugates: Synthesis and Structure -- A. The Carrier Component: Structural Considerations -- B. Conjugates of Amide-Linked Ferrocene -- C. Conjugates of Ester-Linked Ferrocene -- V. Bioactivity Screening -- VI. Summary and Conclusions -- VII. Acknowledgments -- VIII. References -- 7. Polymeric Platinum-Containing Drugs in the Treatment of Cancer -- I. Introduction -- II. Basic Mechanisms of Pt(II) Complex Formation -- III. Nomenclature -- IV. Currently Approved Platinum-Containing Compounds -- V. Properties of Cisplatin -- VI. Structure-Activity Relationships -- VII. Polymer-Drug Conjugation Strategy and Possible Benefits -- A. Polymers as Carriers -- B. Polymers as Drugs -- C. General -- VIII. Mainchain-Incorporated cis-Diamine-Coordinated Platinum -- A. Simple Amine Derivatives -- B. Amino Acid Derivatives -- C. Other Nitrogen-Platinum Products -- D. Solution Stability -- E. Thermal Stability -- F. Antiviral Activity -- IX. Platinum Carrier-Bound Complexes via Nitrogen Donor Ligands -- A. Pt-Polyphosphazenes -- B. Slowly Biofissionable Pt-N Complexes Anchored through Primary and Secondary Amines -- C. Biofissionable Pt-N Complexes Anchored through Primary and Secondary Amines -- X. Pt-O-Bound Polymers -- XI. Mixed Pt-O/Pt-N-Bound Polymers -- XII. Future Work -- XIII. Acknowledgments -- XIV. References -- 8. New Organic Polyacid-Inorganic Compounds for Improved Dental Materials -- I. Introduction -- II. Glass Ionomer Technology -- A. Amino Acid-Modified Glass Ionomers. , B. N-Vinylpyrrolidone (NVP)-Modified Glass Ionomers -- III. New NVP-Modified Glass Ionomers: Experimental Work -- A. Materials -- B. Polymer Synthesis -- C. Characterization -- D. Physical Properties -- IV. Results and Discussion -- V. Conclusions -- VI. References -- Index.

Note: Intro -- Culture of Cold-Water Marine Fish -- Contents -- Preface -- List of Contributors -- 1 Introduction -- 1.1 References -- 2 Abiotic Factors -- 2.1 Introduction -- 2.2 Oxygen and Oxygen Consumption -- 2.3 Ammonia -- 2.4 Temperature -- 2.4.1 Seasonal Temperature Cycle and Spawning -- 2.4.2 Egg and Larval Development -- 2.4.3 Sex Ratio -- 2.4.4 Growth and Metabolism -- 2.5 Salinity -- 2.6 Hydrogen Sulphide -- 2.7 Light -- 2.7.1 Growth and Development -- 2.7.2 Reproduction -- 2.8 Algae Blooms -- 2.9 Site Selection -- 2.10 References -- 3 Microbial Interactions, Prophylaxis and Diseases -- 3.1 Fish-Microbe Interactions and Implications in Aquaculture -- 3.1.1 Disease-Causing Organisms -- 3.1.2 Normal Fish-Microbe Interactions, Infection Pathways and Pathogenesis -- 3.1.3 The Immune System of Fish -- 3.2 Viral Diseases: Diagnosis -- 3.2.1 Infectious Pancreatic Necrosis Virus (IPNV) -- 3.2.2 Nodaviruses -- 3.2.3 Other Viruses -- 3.3 Bacterial Diseases: Diagnosis -- 3.3.1 Vibrio Species -- 3.3.2 Aeromonas Species -- 3.4 Parasitic Protists and Metazoans: Diagnosis, Prophylaxis and Treatment -- 3.4.1 Protists -- 3.4.1.1 Amoebae -- 3.4.1.2 Apicomplexans -- 3.4.1.3 Microsporidia -- 3.4.1.4 Ciliates -- 3.4.1.5 Flagellates -- 3.4.2 Metazoans -- 3.4.2.1 Myxosporidia (Parasitic Cnidarians) -- 3.4.2.2 Monogeneans -- 3.4.2.3 Cestodes -- 3.4.2.4 Trematodes -- 3.4.2.5 Nematodes -- 3.4.2.6 Acanthocephalans -- 3.4.2.7 Leeches -- 3.4.2.8 Crustaceans -- 3.5 A Strategy for Microbial Control -- 3.5.1 General Considerations -- 3.5.2 A Strategy for Microbial Control and Important Elements in such a Strategy -- 3.6 Improving Environmental Conditions -- 3.6.1 Non-Selective Reduction of Microbes -- 3.6.2 The Use of Probiotics -- 3.6.3 Selection for Desirable Bacteria -- 3.7 Improving the Resistance of the Fish -- 3.7.1 Modulation of Specific Immunity-Vaccination. , 3.7.2 Modulation of Non-Specific Immunity -- 3.7.3 The Effect of Nutrition and Genetics on Resistance Against Microbes -- 3.8 Closing Remarks -- 3.9 References -- 4 Live Food Technology of Cold-Water Marine Fish Larvae -- 4.1 Introduction -- 4.2 Cultivation Systems -- 4.3 Production of Rotifers -- 4.3.1 Biological Characteristics -- 4.3.1.1 General Biology and Life History -- 4.3.1.2 Feeding Kinetics of B. plicatilis -- 4.3.1.3 Growth, Mortality and Egg Ratio -- 4.3.2 Cultivation Feed and Feed Treatments -- 4.3.3 Cultivation of Rotifers -- 4.3.3.1 Maintenance of Stock Cultures -- 4.3.3.2 Inoculation Phase -- 4.3.3.3 Early Growth Phase -- 4.3.3.4 Late Growth Phase-Harvesting Strategies -- 4.3.3.5 Production in Batch Culture -- 4.3.3.6 Production in Continuous Culture -- 4.3.4 High-Intensity Rotifer Cultivation -- 4.3.5 Problems in Rotifer Cultivation -- 4.3.5.1 Feeding-Related Problems -- 4.3.5.2 Environmentally Related Problems -- 4.3.5.3 Disease and Contamination -- 4.3.5.4 Problem Identification-Diagnostic Criteria -- 4.3.5.5 Counter-Measures Against Undesirable Situations -- 4.3.6 Biochemical Composition During Steady-State Feeding and Growth -- 4.3.6.1 Proteins and Essential Amino Acids -- 4.3.6.2 Lipids and Essential Fatty Acids -- 4.3.6.3 Vitamins and Minerals -- 4.3.7 Short-Term Enrichment Techniques to Improve Nutritional Value -- 4.3.7.1 Proteins -- 4.3.7.2 Lipids and Fatty Acids -- 4.3.8 Stability of Nutritional Value -- 4.4 Production of Artemia -- 4.4.1 Feeding and Growth -- 4.4.2 Biomass and Biochemical Composition -- 4.4.3 Pre-Enrichment Cultivation -- 4.4.3.1 Disinfection of Cysts -- 4.4.3.2 Decapsulation of Cysts -- 4.4.3.3 Hatching of Cysts -- 4.4.4 Enrichment and Stability of n-3 Fatty Acids -- 4.4.4.1 n-3 HUFA Enrichment -- 4.4.4.2 Stability of n-3 Fatty Acids Post-Enrichment -- 4.4.5 n-3 HUFA of Artemia Juveniles. , 4.4.6 Vitamins and Minerals -- 4.5 Marine Copepods -- 4.6 Concluding Remarks -- 4.7 References -- 5 Brood Stock and Egg Production -- 5.1 Reproductive Strategies -- 5.2 Gonad Maturation -- 5.2.1 Females -- 5.2.2 Males -- 5.2.3 Spawning Once or Many Times? -- 5.2.4 Endocrine Regulation -- 5.3 Brood-Stock Management and Egg Production -- 5.3.1 Brood-stock Nutrition -- 5.3.1.1 Ration Size -- 5.3.1.2 Feed Composition -- 5.3.1.3 Fatty Acids -- 5.3.1.4 Micronutrients -- 5.3.1.5 Pigments and Minerals -- 5.3.2 Photoperiod -- 5.3.3 Temperature -- 5.3.4 Present Husbandry Practices and Egg Collection -- 5.3.4.1 Cod -- 5.3.4.2 Turbot -- 5.3.4.3 Atlantic Halibut -- 5.3.4.4 Wolf-fish -- 5.4 Egg Quality -- 5.4.1 Assessment of Egg Quality -- 5.4.1.1 Egg Morphology -- 5.4.1.2 Fertilisation Success and Cortical Reaction -- 5.4.1.3 Blastomere Morphology -- 5.4.1.4 Egg Size -- 5.4.1.5 Chemical Content -- 5.4.1.6 Cytology -- 5.4.1.7 Oxygen Consumption -- 5.4.1.8 Evaluating Mammalian Embryo Quality -- 5.4.2 Factors Affecting Egg Quality -- 5.4.2.1 Over-ripening -- 5.4.2.2 Viability of Ovulated Eggs in Vivo -- 5.4.2.3 Viability of Ovulated Eggs in Vitro -- 5.4.2.4 Changes in the Eggs -- 5.4.3 Change in Egg Quality Over the Spawning Season -- 5.4.4 Maternal Effects -- 5.4.5 Conclusions -- 5.5 Sperm Production and Quality -- 5.5.1 Features of Sperm Production and Quality -- 5.5.1.1 Morphology -- 5.5.1.2 Gonadosomatic Index and Ejaculate Volume -- 5.5.1.3 Concentration -- 5.5.1.4 Motility -- 5.5.1.5 Fertilising Capacity -- 5.5.1.6 Biochemistry and Oxygen Consumption -- 5.5.2 Influence of Environmental Factors on Sperm Quality -- 5.5.3 Sperm Storage -- 5.6 Selective Breeding -- 5.6.1 Expected Benefits -- 5.6.2 Phenotypic Value and Variance -- 5.6.3 Genotype by Environmental Interaction -- 5.6.4 Breeding Goal -- 5.6.5 Growth Rate -- 5.6.6 Feed Efficiency. , 5.6.7 Disease Resistance -- 5.6.8 Quality -- 5.6.9 Age at Sexual Maturation -- 5.6.10 Base Population and Brood-Stock Development -- 5.6.11 In-breeding -- 5.6.12 Selection Methods -- 5.6.12.1 Individual Selection (Mass Selection) -- 5.6.12.2 Family Selection -- 5.6.12.3 Progeny Testing -- 5.6.12.4 Combined Selection -- 5.6.13 Response to Selection -- 5.6.14 Multi-Trait Selection -- 5.7 Modern Biotechnology and Aquaculture -- 5.7.1 Molecular Pedigree Analysis -- 5.7.2 Genetic Mapping and QTL Analysis -- 5.7.3 Transgenic Fish -- 5.7.4 Future Prospects -- 5.8 References -- 6 From Fertilisation to the End of Metamorphosis-Functional Development -- 6.1 Intervals of Fish Ontogeny and Definitions of the Organism -- 6.1.1 Relative Duration of the Various Stages of Development -- 6.2 Egg Classification -- 6.2.1 Egg Structure and Composition -- 6.3 Insemination and Fertilisation -- 6.4 Embryonic Development and Hatching -- 6.4.1 Cod (Gadus morhua) -- 6.4.2 Wolf-fish (Anarhichas lupus) -- 6.4.3 Embryo Growth and Yolk Absorption -- 6.5 From Hatching to Metamorphosis -- 6.5.1 To Be a Larva . . . -- 6.5.2 . . . or Not to Be a Larva -- 6.5.3 The Yolk-Sac Period-Preparation for 'Real Life' -- 6.5.4 Metamorphosis -- 6.6 Functional Development of Organ Systems from Hatching to Metamorphosis -- 6.6.1 Sensory System -- 6.6.1.1 Vision and the Oculovestibular System -- 6.6.1.2 Chemosensory System -- 6.6.1.3 Lateral Line -- 6.6.2 Digestive System -- 6.6.2.1 Gut, Pancreas and Liver Differentiation -- 6.6.2.2 Digestive Enzymes -- 6.6.2.3 Digestive Physiology„Lipids, Proteins and Carbohydrates -- 6.6.2.4 Stomach Development and Metamorphosis -- 6.6.3 Muscle and Body Skeleton -- 6.6.3.1 Swimming Capacity and Muscle Development -- 6.6.3.2 Musculature Changes During Metamorphosis -- 6.6.3.3 Skeletal Changes -- 6.6.4 Swim-bladder -- 6.6.5 Osmoregulation. , 6.6.6 Respiration and Excretion -- 6.6.7 Neuroendocrine Systems -- 6.6.8 Growth Hormone, Prolactin and Cortisol -- 6.6.9 The Immune System -- 6.6.10 Skin and Pigmentation -- 6.6.11 Larval Feeding Behaviour -- 6.6.12 Larval Growth -- 6.6.12.1 How Can We Express Larval Growth? -- 6.6.13 Influence of Diet -- 6.6.14 Juvenile Quality -- 6.7 Hatchery Design -- 6.7.1 The Demersal Eggs of Wolf-fish -- 6.7.2 Pelagic Eggs (Cod, Turbot, Halibut) -- 6.7.2.1 Cod -- 6.7.2.2 Turbot -- 6.7.2.3 Halibut -- 6.8 Critical Aspects of Larval Cultivation -- 6.9 References -- 7 First Feeding Technology -- 7.1 Introduction -- 7.2 Nutritional Requirements of Marine Fish Larvae -- 7.2.1 Essential Fatty Acids -- 7.2.2 Main Lipid Classes -- 7.2.3 Physiological Basis of n-3 HUFA Requirements -- 7.2.4 Protein and Essential Amino Acids -- 7.2.5 Protein Versus Lipid Nutrition -- 7.3 Definitions and System Description -- 7.3.1 Extensive Systems: Large Closed Nature-like Systems -- 7.3.2 Semi-intensive Systems: Large Suspended Mesocosms, Enclosures or Outdoor Tanks -- 7.3.3 Larval Rearing in Relatively Small Tanks: Classical Intensive Hatchery Techniques -- 7.3.3.1 Water Treatment and Supply -- 7.3.3.2 Production Lines for Live Feed -- 7.3.3.3 Larval Rearing Systems -- 7.3.3.4 Automation and Process Control -- 7.4 Larval Rearing in 'Nature-like' Systems -- 7.4.1 Pioneer Work -- 7.4.2 The 'Lagoon Method' as a Production System -- 7.4.3 Larval Food and Feeding in Mesocosms -- 7.4.3.1 Initiation of Exogenous Feeding: The 'Green Gut' -- 7.4.3.2 Prey Selection -- 7.4.3.3 Feeding, Growth and Survival -- 7.5 Larval First Feeding in Intensive Systems -- 7.5.1 Physical Chemical Environment -- 7.5.2 Feeding Characteristics of Fish Larvae -- 7.5.2.1 Food Selection -- 7.5.2.2 Feeding and Functional Response -- 7.5.2.3 Larval Feeding Rate of Live Feed -- 7.5.2.4 Larval Feeding on Microalgae. , 7.5.3 Feeding Regime Components for Cold-water Larviculture.

Note: Front Cover -- Surfaces and their Measurement -- Copyright Page -- Contents -- Foreword -- Chapter 1. Introduction -- 1.1 General -- 1.2 What is surface metrology? -- 1.3 Usefulness of surfaces -- 1.4 Nature of surfaces -- Chapter 2. Identification and separation of surface features -- 2.1 Visualization -- 2.2 Profiles and roughness - understanding the measurement routine -- 2.3 Waviness -- 2.4 Implementing the concept of sampling length -- 2.5 The shape of the reference line -- 2.6 Other methods -- 2.7 Filtering and M system -- 2.8 Conclusions -- Chapter 3. Profile and areal (3D) parameter characterization -- 3.1 Specification -- 3.2 Classification of parameters for the profile -- 3.3 Random process analysis -- 3.4 Areal (3D) assessment -- 3.5 Space frequency functions -- 3.6 Comments on digital areal analysis -- 3.7 Two-dimensional filtering (areal filtering) -- 3.8 Fractal surfaces -- 3.9 Summary of characterization -- Chapter 4. Surface metrology and manufacture -- 4.1 Where and when to measure -- 4.2 The process and surface finish -- 4.3 Process control -- 4.4 Relationship between surface metrology and manufacture -- 4.5 Force and metrology loops -- 4.6 Unit events and autocorrelation -- 4.7 Use ofthe power spectrum -- 4.8 Application of space frequency functions -- 4.9 Conclusions -- Chapter 5. Function and surface texture -- 5.1 Generic approach -- 5.2 Some specific examples in tribology -- 5.3 Surface models -- 5.4 Summary of function -- Chapter 6. Surface finish measurement - general -- 6.1 Some quick ways of examining the surface -- 6.2 Surface finish instrumentation -- 6.3 Comments -- Chapter 7. Stylus instruments -- 7.1 The stylus -- 7.2 Reference -- 7.3 Use of skids -- 7.4 Pick-up systems -- 7.5 Stylus damage -- 7.6 Stylus instrument usage -- Chapter 8. Optical methods -- 8.1 Optical path length -- 8.2 Optical penetration. , 8.3 Resolution and depth of focus -- 8.4 Comparison between optical and stylus methods -- 8.5 Gloss meters -- 8.6 Total integrating sphere -- 8.7 Diffractometer -- 8.8 Interferometry -- 8.9 Optical followers -- 8.10 Heterodyne method -- 8.11 Other optical methods -- 8.12 Conclusions from the comparison of tactile and optical methods -- Chapter 9. Scanning microscopes -- 9.1 General -- 9.2 Scanning microscopes -- 9.3 Operation of the STM -- 9.4 The atomic force microscope -- 9.5 Scanning microscopes: conclusions -- 9.6 Instruments 'horns of metrology' : conclusions -- Chapter 10. Errors of form (excluding axes of rotation) -- 10.1 General statement -- 10.2 Straightness and related topics -- 10.3 Measurement -- 10.4 Assessment and classification of straightness -- 10.5 Flatness -- 10.6 Conclusions -- Chapter 11. Roundness and related subjects -- 11.1 General -- 11.2 Direction of measurement -- 11.3 Display of roundness -- 11.4 Lobing -- 11.5 Methods of measuring roundness -- 11.6 Nature of the roundness signal -- 11.7 Assessment of roundness -- 11.8 Partial arc determination -- 11.9 Other parameters -- 11.10 Filtering for roundness -- 11.11 Harmonic problems -- 11.12 Alternatives to harmonic analysis -- 11.13 Non-roundness parameters -- 11.14 Conclusions -- Chapter 12. Cylindricity, sphericity -- 12.1 Cylindricity -- 12.2 Configurations for measurement -- 12.3 Some definitions of cylindrical parameters -- 12.4 Assessment -- 12.5 Other points on cylinders -- 12.6 Sphericity -- 12.7 Partial sphericity -- 12.8 Wankel - other shapes -- Chapter 13. Metrology instrument design and operation for minimum error -- 13.1 Introduction -- 13.2 Capability -- 13.3 Errors -- 13.4 Metrology instrument design and error reduction -- 13.5 Instrument usage -- 13.6 Elastic design - removal of hysteresis and friction errors -- 13.7 Workpiece cleaning and handling. , 13.8 Conclusions -- Chapter 14. Calibration of instruments -- 14.1 General -- 14.2 The stylus calibration -- 14.3 Height calibration -- 14.4 General height -- 14.5 Roundness calibration - for height -- 14.6 Filter calibration (type C standard) -- 14.7 Vibrating tables -- 14.8 Instrument comparisons -- 14.9 Chain of standards -- 14.10 Conclusions -- Chapter 15. Sampling, numerical analysis, display -- 15.1 General -- 15.2 Numerical model -- 15.3 Sampling criteria -- 15.4 Error of application -- 15.5 Representation on drawing -- 15.6 Sample guides -- 15.7 Philosophical background to standards in roughness -- 15.8 Concluding remarks -- Glossary -- Index -- Color Plate Section.