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  • 1
    Electronic Resource
    Electronic Resource
    Interventional Occlusion of a Large Pulmonary Arteriovenous Malformation with an Amplatzer Septal Occluder (2003)
    350 Main Street, Malden, MA 02148, USA. : Blackwell Futura Publishing, Inc.
    Journal of interventional cardiology 16 (2003), S. 0 
    Details
    ISSN: 1540-8183
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Interventional occlusion of pulmonary arteriovenous malformations with large feeding arteries may be associated with an increased risk of device embolization. In a 40-year-old patient with a solitary pulmonary arteriovenous malformation one large feeding artery was successfully closed by means of an Amplatzer septal occluder and detachable coils. The use of an Amplatzer septal occluder should be considered as an alternative therapeutic option in cases of huge pulmonary arteriovenous malformation to reduce the risk of device embolization. (J Interven Cardiol 2003;16:335–339)
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-6143.2003.08056.x
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  • 2
    Electronic Resource
    Electronic Resource
    Comparison of a Silicon Carbide Coated Stent versus a Noncoated Stent in Humans: (2003)
    350 Main Street, Malden, MA 02148, USA. : Blackwell Futura Publishing, Inc.
    Journal of interventional cardiology 16 (2003), S. 0 
    Details
    ISSN: 1540-8183
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Purpose: Stents coated with hypothrombogenic silicon carbide (a-SiC:H) exhibited low restenosis rates in the rabbit and in an observational study in humans. Thus, the clinical and angiographic outcome was assessed in a large multicenter study. Material and Methods: Four hundred and ninety-seven patients (63.4 ± 9.8 years) were randomized to either receive the a-SiC:H-coated Tenax™ stent or the stainless steel Nir™ stent. Lesions (diameter ≥2.8 mm, length 〈20 mm) were covered with one single stent. Results: Fifty-one of 497 (10.3%) patients were excluded for protocol violation. Three hundred and forty-two of 446 (76.7%) patients presented for scheduled angiographic follow-up after 4.7 ± 1.2 months and 29 of 446 (6.5%) prematurely. In-hospital complications comprised two deaths (0.8%) (P 〉 0.99) and one (0.4%) (P 〉 0.99) CK-elevation in each group, target lesion revascularization in 5 of 250 (2%) of the Tenax™ and 4 of 244 (1.6%) of the Nir™ sample (P 〉 0.99), and subacute thrombosis in 2 of 250 (0.8%) of the Tenax™ patients (P = 0.5). In the Tenax™/Nir™ patients mean percent diameter stenosis decreased from 82.3 ± 9.1%/80.7 ± 8.4% (P = 0.49) to 17.6 ± 5.5%/17.6 ± 5.5% (P = 0.99) postprocedure and increased to 34.5 ± 21.5%/34.2 ± 23.1% (P = 0.90) at follow-up. Conclusions: Thus, there appears to be no advantage of the silicon carbide coated stent over a stainless steel stent after 4.7 ± 1.2 months with regard to clinical and angiographic restenosis rates. (J Interven Cardiol 2003;16:325–333)
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-6143.2003.08058.x
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  • 3
    Electronic Resource
    Electronic Resource
    Percutaneous, Catheter-Based Coil Embolization of Coronary Fistula: (2003)
    350 Main Street, Malden, MA 02148, USA. : Blackwell Futura Publishing, Inc.
    Journal of interventional cardiology 16 (2003), S. 0 
    Details
    ISSN: 1540-8183
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A 55-year-old male with angina-like chest pain and positive thallium-scintigraphy was admitted to our hospital. Cardiac catheterization was performed for suspected coronary artery disease. The coronary angiogram showed no significant epicardial stenosis, but a large coronary fistula, connecting the left anterior descending artery with the pulmonary artery. Swan–Ganz catheter measurements, intracoronary Doppler, and quantitative coronary angiography were used to determine cardiac output, coronary blood flow, and coronary-to-pulmonary artery shunt fraction. These measurements showed a hyperdynamic cardiac output of 17 L/min, a coronary blood flow of 140 mL/min in the left anterior descending coronary artery with an estimated shunt fraction of 58% into the pulmonary circulation. Percutaneous, catheter-based coil embolization was performed to occlude the fistula. After embolization of one coil, coronary angiography showed the fistula's stump only. Cardiac output (9 L/min) and coronary blood flow (48 mL/min) were almost normalized. The patient was discharged from the hospital the day after the procedure. After a 6-month follow-up, there were still no complaints, angina-like symptoms or signs of myocardial ischemia in stress tests. (J Interven Cardiol 2003;16:343–346)
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-6143.2003.08053.x
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  • 4
    Electronic Resource
    Electronic Resource
    The Artery: (2003)
    350 Main Street, Malden, MA 02148, USA. : Blackwell Futura Publishing, Inc.
    Journal of interventional cardiology 16 (2003), S. 0 
    Details
    ISSN: 1540-8183
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-6143.2003.08057.x
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  • 5
    Electronic Resource
    Electronic Resource
    Acute and Long-Term Outcomes of Rotational Atherectomy in Small (〈3.0 mm) Coronary Arteries (2003)
    350 Main Street, Malden, MA 02148, USA. : Blackwell Futura Publishing, Inc.
    Journal of interventional cardiology 16 (2003), S. 0 
    Details
    ISSN: 1540-8183
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Conventional balloon angioplasty (BA) of small coronary arteries (SCA) is followed by a high rate of restenosis. Rotational atherectomy may be effective as an alternate treatment of stenoses unsuitable for other devices. The purpose of this study was to assess the efficacy of RA in the treatment of SCA. A retrospective analysis was performed of 226 lesions in 159 consecutive patients who underwent RA of SCA (mean diameter = 2.36 ± 0.49 mm). One hundred forty-eight lesions (65.5%) were type B2 or C of AHA/ACC criteria. Follow-up angiography was performed at 3 and 6 months after the procedure. Procedural success was achieved in 96.9% of patients. The mean burr-to-artery ratio was 0.74 ± 0.17. Adjunctive BA and stent implantation were needed in 94.2% and 22.6% of lesions, respectively. Minimal lumen diameter (MLD) increased from 0.66 ± 0.35 mm to 1.97 ± 0.58 mm (P 〈 0.01). Angiographic complications consisted of acute reclosure (3.5%), no reflow/slow flow (12.4%), and coronary artery perforation (1.8%). No death, Q-wave myocardial infarction (MI), or coronary artery bypass graft (CABG) occurred during the initial hospitalization. Restenosis rates at 3 and 6 months were 40.6% and 44.2%, respectively, and target lesion revascularization (TLR) rates were 28.5% and 33.0%, respectively. Restenosis and TLR rates during follow-up were comparable among patients who underwent RA + adjunctive BA versus patients who underwent RA + stenting. Long-term clinical follow-up was complete in 143 patients over a mean period of 348 ± 166 days. The survival free from cardiac death, MI, CABG or repeated BA was 59.6% at 1 year. In conclusion, RA of SCA has relatively high restenosis rates, but may be appropriate for more complex, calcified lesions unsuitable for other devices. (J Interven Cardiol 2003;16:315–322)
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-6143.2003.08059.x
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  • 6
    Electronic Resource
    Electronic Resource
    Previous Cytomegalovirus Infection and Restenosis after Aggressive Angioplasty with Provisional Stenting (2003)
    350 Main Street, Malden, MA 02148, USA. : Blackwell Futura Publishing, Inc.
    Journal of interventional cardiology 16 (2003), S. 0 
    Details
    ISSN: 1540-8183
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objectives : The aim of this study was to determine the impact of previous infection with cytomegalovirus (CMV) on restenosis after aggressive angioplasty with provisional stenting. Design: We prospectively studied 78 consecutive patients scheduled for 6-month follow-up coronary angiography as part of the SIPS study. Anti-CMV IgG and IgM antibodies were measured on admission. Results: Anti-CMV IgG positive and anti-CMV IgG negative patients had similar minimal lumen diameter (MLD) in the target vessel before (0.68 ± 0.49 mm vs 0.71 ± 0.52 mm, P = 0.84) and directly after the intervention (2.50 ± 0.60 mm vs 2.57 ± 0.52 mm, P = 0.58). After 6 months, however, the MLD was significantly smaller in CMV-positive as compared to CMV-negative patients (1.57 ± 0.82 mm vs 2.00 ± 0.83 mm, P 〈 0.03). Net lumen gain at 6 months was significantly lower in CMV-positive patients (0.89 ± 0.79 mm vs 1.30 ± 0.87 mm, P 〈 0.04) and the rate of clinically relevant restenosis was significantly higher (31% vs 7%, P 〈 0.02). In a multivariate logistic regression model, CMV seropositivity was an independent predictor of restenosis (odds ratio 5.7 (95%CI 1.2–30.3, P = 0.04). Conclusions: Six months after aggressive coronary angioplasty with provisional stenting, patients with prior CMV infection had a smaller MLD and a higher restenosis rate. CMV seropositivity was a strong independent predictor of restenosis. (J Interven Cardiol 2003;16:307–313)
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-6143.2003.08060.x
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  • 7
    Electronic Resource
    Electronic Resource
    Current Perspectives in Therapeutic Myocardial Angiogenesis (2003)
    350 Main Street, Malden, MA 02148, USA. : Blackwell Futura Publishing, Inc.
    Journal of interventional cardiology 16 (2003), S. 0 
    Details
    ISSN: 1540-8183
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The complex mechanisms mediating the development of new blood vessels are now beginning to be unraveled. In conjunction with major biotechnology advances, this has facilitated the initiation of translational research related to a novel treatment strategy for patients with myocardial or leg ischemia due to obstructive arterial disease—therapeutic angiogenesis. At present, at least 17 clinical trials of myocardial angiogenesis have been presented involving over 900 patients. Uncertainty exists as to the optimal delivery route and angiogenic agent, and this uncertainty is reflected in the diverse methodology of the trials published thus far. The majority of patients received an angiogenic protein via the intracoronary route. Other delivery techniques—such as direct intramyocardial injection via transepicardial or transendocardial routes—and other angiogenic agents, including master genes, have also been studied. Most recently, interest has grown in the potential angiogenesis effects of cell therapy—such as autologous bone marrow cells or cultured stem cells—and there are now several groups initiating Phase I/II trials in this area. This review summarizes the current evidence pertaining to the safety, feasibility, and efficacy of various angiogenic techniques aimed at enhancing myocardial blood flow and alleviating angina. (J Interven Cardiol 2003;16:289–297)
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-6143.2003.08061.x
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  • 8
    Electronic Resource
    Electronic Resource
    Mortality Benefit of Beta Blockade in Patients with Acute Coronary Syndromes Undergoing Coronary Intervention: (2003)
    350 Main Street, Malden, MA 02148, USA. : Blackwell Futura Publishing, Inc.
    Journal of interventional cardiology 16 (2003), S. 0 
    Details
    ISSN: 1540-8183
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The effects of beta blocker therapy in the settings of heart failure and coronary artery disease have been well described, although little data exist in patients presenting with acute coronary syndromes undergoing percutaneous coronary intervention. The current study will attempt to evaluate the efficacy of beta blocker therapy in this setting. Pooled data from five randomized, controlled trials of abciximab during coronary intervention were used to analyze the clinical efficacy of beta blocker therapy. The pooled analysis evaluated the end points of all-cause mortality, myocardial infarction, repeat revascularization, and the combined endpoint of death and myocardial infarction in 2,894 patients. At 30 days, death occurred in 12 of 1,939 (0.6%) patients receiving beta blocker therapy and in 19 of 955 (2.0%) patients not receiving beta blocker therapy, (P 〈 0.001). At 6 months, death occurred in 33 of 1,939 (1.7%) patients receiving beta blocker therapy and 35 of 955 (3.7%) not receiving beta blocker therapy, (P 〈 0.001). After creating a propensity model and adjusting for variables predictive of mortality in the multivariable analysis, beta blocker therapy continued to be associated with a significant reduction in mortality. The findings were similar to those shown for the effects of beta blocker therapy in separate subgroups of patients with unstable angina and acute myocardial infarction. This analysis demonstrates a lower short-term mortality in patients receiving beta blocker therapy who undergo percutaneous coronary intervention for unstable angina or acute myocardial infarction. (J Interven Cardiol 2003;16:299–305)
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-6143.2003.08062.x
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  • 9
    Electronic Resource
    Electronic Resource
    ICD Nocardiosis (2003)
    350 Main Street , Malden , MA 02148 , USA . : Blackwell Futura Publishing, Inc.
    Journal of interventional cardiology 16 (2003), S. 0 
    Details
    ISSN: 1540-8183
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We present an initial report of Nocardia asteroides implantable cardioverter defibrillator infection. Systemic infection persisted despite pulse generator explant and several years of appropriate antibiotic therapy. Without epicardial lead system removal, chronic pleuropericardial disease developed. (J Interven Cardiol 2003;16:375–376)
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1540-8183.2003.00169.x
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  • 10
    Electronic Resource
    Electronic Resource
    Another Arrow in the Quiver — But at What Cost? (2003)
    350 Main Street, Malden, MA 02148, USA. : Blackwell Futura Publishing, Inc.
    Journal of interventional cardiology 16 (2003), S. 0 
    Details
    ISSN: 1540-8183
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-6143.2003.08055.x
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