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  • 1
    Online Resource
    Online Resource
    Cham : Springer
    Keywords: Microbiology ; Emerging infectious diseases ; Medicine ; Infectious diseases. ; Medical Microbiology ; Health promotion. ; Medicine, Preventive. ; Diseases. ; Buruli Ulcer epidemiology ; Buruli Ulcer therapy
    Description / Table of Contents: Buruli Ulcer: History and Disease Burden -- Buruli Ulcer in Africa -- Buruli Ulcer in Australia -- Mycobacterium Ulcerans Infection in French Guiana; Current State of Knowledge -- Buruli Ulcer in Japan -- Population Genomics and Molecular Epidemiology of Mycobacterium Ulcerans -- Mycolactone: More Than Just a Cytotoxin -- The Immunology of Buruli Ulcer -- Buruli Ulcer in Animals and Experimental Infection Models -- Laboratory Diagnosis of Buruli Ulcer: Challenges and Future Perspectives -- Antimicrobial Treatment of Mycobacterium Ulcerans Infection -- Thermotherapy of Buruli Ulcer -- Secondary Infection of Buruli Ulcer Lesions -- Management of BU-HIV Co-infection -- Social Science Contributions to BU Focused Health Service Research in West-Africa -- Transdisciplinary Research and Action to Stop Buruli Ulcer– A Case Study from Philanthropy
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource (X, 287 p. 34 illus., 30 illus. in color)
    ISBN: 9783030111144
    Series Statement: Springer eBooks
    Language: English
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  • 2
    Keywords: Medicine ; Molecular Medicine ; Pharmaceutical technology ; Biomedical engineering ; Diabetes ; Molecular biology. ; Lipoproteins, HDL ; Biomarkers
    Description / Table of Contents: Preface -- Chapter 1. Understanding HDL: overview -- 1-1.HDL and disease -- 1-2.HDL functions and clinical applications -- 1-3.HDL composition : apolipoproteins and enzymes -- 1-4.Maturation of HDL -- 1-5.HDL and blood pressure -- Chapter 2. Change of HDL by life style -- 2-1.Exercise and HDL -- 2-2.Smoking and HDL -- 2-3.Elderly’s HDL -- 2-4.HDL depends on body weight -- 2-5.HDL from obese but healthy subject -- 2-6.HDL and apoA-I in smokers’ breast milk -- 2-7.Breast milk from frequent trans fatty acid consumers -- 2-8.HDL in cord blood from small neonates -- Chapter 3. Change of HDL in various diseases -- 3-1.HDL from patients with myocardial infarction -- 3-2.HDL from patients with female angina pectoris -- 3-3.HDL and metabolic syndrome -- 3-4.HDL from male patients with atrial fibrillation -- 3-5.HDL from female patients with atrial fibrillation -- 3-6.HDL from patients with hemorrhagic fever with renal syndrome -- 3-7.HDL from patients with rheumatoid arthritis -- 3-8.HDL and prehypertension -- Chapter 4. Detriment of HDL by pollutant and its evaluation -- 4-1.Particulate matter and HDL -- 4-2.Phthalate and HDL -- 4-3.Cadmium and HDL -- 4-4.Humidifier Sterilizer and HDL -- 4-5.Detection of dysfunctional HDL by microfluidics -- 4-6.Evaluation of dysfunctional HDL using zebrafish embryo -- Chapter 5. Change of HDL by food ingredient -- 5-1.Fructose and apoA-I -- 5-2.Fructose and impairment of HDL functionality -- 5-3.Artificial sweeteners and apoA-I -- 5-4.Artificial sweeteners (aspartame, saccharin) and HDL -- 5-5.Aldoketohexoses and HDL -- 5-6.Iron and HDL -- 5-7.Trans fat and HDL -- 5-8.Salt and HDL 576 p -- Summary and perspectives
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource (XXIV, 383 p. 244 illus)
    ISBN: 9789811373879
    Series Statement: Springer eBooks
    Language: English
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  • 3
    Keywords: Medicine ; Molecular Medicine ; Pharmaceutical technology ; Biomedical engineering ; Diabetes ; Molecular biology. ; Lipoproteins, HDL ; Biomarkers
    Description / Table of Contents: Chapter 1. Improvement of HDL -- 1-1.Clinical application of HDL: Overview -- 1-2.Regression effect of V156K-apoA-I -- 1-3.Anti-diabetic effect of V156K-apoA-I -- 1-4.Vitamin C and HDL -- 1-5.Growth hormone-1 in HDL -- 1-6.Growth hormone-2 in HDL -- 1-7.Omega-3 and HDL -- Chapter 2. HDL as therapeutic tools -- 2-1.Delivery vehicle for therapeutics : Overview -- 2-2.Gene delivery: adenovirus and V156K-apoA-I -- 2-3.Solubilization of rapamycin and delivery -- 2-4.Solubilization of minoxidil and delivery -- Chapter 3. Enhancement of HDL by policosanol: anti-aging and longevity -- 3-1.Policosanol and HDL functionality -- 3-2.Policosanol and raising HDL in zebrafish -- 3-3.Policosanol and CETP inhibition: human trial 8 weeks -- 3-4.Policosanol and blood pressure lowering: human trial 8 weeks -- 3-5.Policosanol blood pressure lowering human trial for 24 weeks -- 3-6.Policosanol and improvement of aortic stiffness -- 3-7.Policosanol and blood pressure lowering in rat model -- 3-8.Twelve week consumption of policosanol and lowering blood pressure -- 3-9.Publication analysis of policosanol-related studies -- 3-10.Athero-protective effects of policosanol and sugar cane wax acid -- 3-11.Cuban sugarcane wax acids and policosanol improved serum lipid profiles -- Summary and perspectives -- Epilogue
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource (XVI, 268 p. 174 illus)
    ISBN: 9789811373831
    Series Statement: Springer eBooks
    Language: English
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  • 4
    Keywords: Biomedicine general ; Medicine ; Medicine—Research. ; Biology—Research.
    Description / Table of Contents: Methods and Models for Studying Immunosenescence -- Methods for studying human immunosenescence in tissues other than blood -- Mechanisms - Receptors and Signal Transduction -- Clinical Relevance in Disease States – Infection -- Modulation -- Nutrition
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource (272 illus., 161 illus. in color. eReference)
    Edition: 2nd ed. 2019
    ISBN: 9783319993751
    Series Statement: Springer eBooks
    Language: English
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  • 5
    Online Resource
    Online Resource
    Cham : Springer
    Keywords: Microbiology ; Medicine ; Emerging infectious diseases ; Medical Microbiology ; Health promotion. ; Infectious diseases. ; Biological Warfare prevention & control ; Biological Warfare Agents
    Description / Table of Contents: Diagnostics, Therapeutics and Other Potential Strategies of Biodefense -- Advanced Molecular Biology Tools & Diagnostics -- High Containment Infectious Disease Laboratories as an Integral Part of Emergency Preparedness -- Decontamination Capabilities and Facilities -- Virogenomics as a Tool for Molecular Epidemiology and Forensics -- Next Generation Sequencing Tools for Pathogen Detection -- Metagenomics -- Point-of-care Diagnostic Facilities for Outbreak Intervention -- Psychological Impact of Biological Attacks -- Public-health Preparedness -- Viral Therapeutics -- Bacterial Therapeutics -- Emergency Training for Veterinary Professionals -- Global Biodefense Coordination
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource (XIII, 383 p. 30 illus., 25 illus. in color)
    ISBN: 9783030030711
    Series Statement: Springer eBooks
    Language: English
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  • 6
    Online Resource
    Online Resource
    Singapore : Springer
    Keywords: Medicine ; Statistics ; Bioinformatics ; Computational Biology methods ; Sequence Analysis, DNA ; Databases, Genetic ; Oligonucleotide Array Sequence Analysis
    Description / Table of Contents: Part 1. BIOINFORMATICS FOR LIFE AND PERSONAL GENOME INTERPRETATION -- Chapter 1. Bioinformatics For Life -- Chapter 2. Next Generation Sequencing and Personal Genome Data Analysis -- Chapter 3. Personal Genome Data Analysis -- Chapter 4. Personal Genome Interpretation and Disease Risk Prediction -- Part 2. ADVANCED MICROARRAY DATA ANALYSIS -- Chapter 5. Advanced Microarray Data Analysis -- Chapter 6. Gene Expression Data Analysis -- Chapter 7. Gene Ontology and Biological Pathway-based Analysis -- Chapter 8. Gene-set Approaches and Prognostic Subgroup Prediction -- Chapter 9. MicroRNA Data Analysis -- Part 3. NETWORK BIOLOGY, SEQUENCE, PATHWAY AND ONTOLOGY INFORMATICS -- Chapter 10. Network Biology, Sequence, Pathway and Ontology Informatics -- Chapter 11. Motif and Regulatory Sequence Analysis -- Chapter 12. Molecular Pathways and Gene Ontology -- Chapter 13. Biological Network Analysis -- Part 4. SNPS, GWAS AND CNVS, INFORMATICS FOR GENOME VARIANTS -- Chapter 14. SNPs, GWAS, CNVs: Informatics for Human Genome Variations -- Chapter 15. SNP Data Analysis -- Chapter 16. GWAS Data Analysis -- Chapter 17. CNV Data Analysis -- Part 5. METAGENOME AND EPIGENOME, BASIC DATA ANALYSIS -- Chapter 18. Metagenome and Epigenome Data Analysis -- Chapter 19. Metagenome Data Analysis -- Chapter 20. Epigenome Databases and Tools -- Chapter 21. Epigenome Data Analysis -- Appendix A. BASIC PRACTICE USING R FOR DATA ANALYSIS -- Appendix B. APPLICATION PROGRAM FOR GENOME DATA ANALYSIS INSTALL GUIDE
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource (XVI, 367 p. 645 illus., 236 illus. in color)
    ISBN: 9789811319426
    Series Statement: Learning Materials in Biosciences
    Language: English
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  • 7
    Keywords: Medicine ; Biochemistry ; Gene Function ; Medical genetics ; Neurosciences ; Proteins . ; Molecular biology. ; Progranulins ; Central Nervous System Diseases physiopathology ; Central Nervous System physiopathology ; Biomarkers analysis ; Neuroprotection
    Description / Table of Contents: Chapter 1. Molecular and Functional Properties of Progranulin -- Chapter 2. Progranulin as a biomarker for neurodegenerative diseases -- Chapter 3. PGRN and FTLD -- Chapter 4. PGRN and neurodegenerative diseases other than FTLD -- Chapter 5. Progranulin Regulations of Lysosomal Homeostasis and its Involvement in Neurodegenerative Diseases -- Chapter 6. Molecular and Functional Properties of Progranulin -- Chapter 7. PGRN and neuroinflammation -- Chapter 8. Neural Stem/Progenitor Cells and Progranulin -- Chapter 9. Generation and phenotyping of progranulin-deficient mice -- Chapter 10. Pleiotropic protective effects of progranulin in the treatment of ischemic stroke -- Chapter 11. New therapeutic approaches against ocular diseases
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource (VII, 183 p. 37 illus., 13 illus. in color)
    ISBN: 9789811361869
    Series Statement: Springer eBooks
    Language: English
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  • 8
    Online Resource
    Online Resource
    Cham : Springer
    Keywords: Oncology ; Medicine ; Cytology ; Human genetics ; Cancer Research ; Molecular biology. ; Cell biology. ; Neoplasm Metastasis ; Tumor Hypoxia
    Description / Table of Contents: Preface -- Hypoxia mediates tumor malignancy -- Clinical methods for quanitifying hypoxia in human tumors -- Hypoxia-induced phenotypes that mediate tumor heterogeneity -- Hypoxia and the tumors secretome -- Hypoxic signaling in angiogenesis and lymphangiogenesis -- Hypoxia induced metabolic reprogramming in cancer metastasis -- The metastatic niche and hypoxia -- Hypoxia and immune suppression -- Hypoxia-induced resistance to cancer therapy -- Therapeutic stratagies to target the hypoxic microenvironment -- Index
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource (VIII, 160 p. 17 illus., 16 illus. in color)
    Edition: 1st ed. 2019
    ISBN: 9783030127343
    Series Statement: Advances in Experimental Medicine and Biology 1136
    Language: English
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  • 9
    Keywords: Molecular Medicine ; Medicine ; Statistical methods ; Psychic research ; Animal behavior ; Science ; Statistics ; Biostatistics. ; Science education. ; Molecular biology. ; Experiential research. ; Behavioral sciences. ; Science Study and teaching ; Biology—Research. ; Biometry. ; Medicine—Research. ; Psychology. ; Psychobiology. ; Human behavior.
    Description / Table of Contents: Part I -- Basic Probability Theory -- Experimental Design and the Basics of Statistics: Signal detection Theory (SDT) -- The Core Concept of Statistics -- Variations on the t-test -- PART II -- The Multiple Testing Problem -- ANOVA -- Experimental design: Model Fits, Power, and Complex Designs -- Correlation -- PART III -- Meta-analysis -- Understanding replication -- Magnitude of excess success -- Suggested improvements and challenges
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource (XI, 142 p. 35 illus., 29 illus. in color)
    Edition: 1st ed. 2019
    ISBN: 9783030034993
    Series Statement: Learning Materials in Biosciences
    Language: English
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  • 10
    Online Resource
    Online Resource
    Cham : Springer
    Keywords: Oncology ; Medicine ; Cytology ; Biomedical engineering ; Cancer Research ; Cell biology. ; Molecular biology. ; Neoplasms ; Disease Models, Animal ; Drosophila melanogaster
    Description / Table of Contents: Prelims -- Drosophila model in cancer: an introduction -- Using Drosophila models and tools to understand the mechanisms of novel human cancer driver gene function -- The initial stage of tumorigenesis in Drosophila epithelial tissuesi -- Drosophila models of cell polarity and cell competition in tumourigenesis -- Two sides of the same coin – compensatory proliferation in regeneration and cancer -- P53 and apoptosis in the Drosophila model -- Autophagy and tumorigenesis in Drosophila -- Filling the gaps among obesity, the CDK8 module, and uterine tumors using Drosophila -- MicroRNAs in Drosophila cancer models -- Cancer Stem Cells and Stem Cell Tumors in Drosophila -- Drosophila as a model for tumor-induced organ wasting -- Drosophila melanogaster as a model system for human glioblastomas -- What Drosophila Can Teach Us About Radiation Biology of Human Cancers -- Drosophila based cancer drug discovery frameworkIn -- Index
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource (VI, 250 p. 56 illus., 55 illus. in color)
    Edition: 1st ed. 2019
    ISBN: 9783030236298
    Series Statement: Advances in Experimental Medicine and Biology 1167
    Language: English
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