Publication Date:
2012-08-14
Description:
We read with great interest the letter to the editor by Guiu and Cercueil 1 referring to our study on invasive and non-invasive methods in quantifying liver fat content. 2 The authors commented on the MRI T2*-bias associated with presence of iron in the liver. They contend that multi-echo (ME) rather than dual-echo (DE) sequences are superior, and indicate the potential confounding effect of a relatively high flip angle and T1 bias associated with the sequences used in our study. Furthermore, they emphasise the need for international guidelines regarding sequences used by MRI for the quantification of liver fat content. Indeed, our study is compromised by the limitations of fat quantification using a standard DE sequence in comparison with the newly proposed ME-MRI with correction for T2*-bias. 3 We were aware of these limitations as the availability of these sequences is vendor-dependent and they were not...
Print ISSN:
0017-5749
Electronic ISSN:
1468-3288
Topics:
Medicine
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