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  • Articles  (175)
  • PAPER CURRENT  (175)
  • 2015-2019  (175)
  • 2016  (175)
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  • Articles  (175)
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  • PAPER CURRENT  (175)
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  • 2015-2019  (175)
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  • 1
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    Data on the optimizations of expression and purification of human BiP/GRP78 protein in Escherichia coli (2016)
    Elsevier
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    Publication Date: 2016-12-30
    Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Jiao Yang, Lei Zhou, Qinglian Liu Human BiP/GRP78 is involved in the folding and assembly of proteins in the endoplasmic reticulum. The proteins for crystallization in good amount and quality are prerequisites for obtaining ideal crystals. To meet these requirements, different BiP/GRP78 constructs, competent cells, vectors, and concentrations of inducer were tested in order to obtain soluble BiP/GRP78 protein with the highest amount and best purity. The BiP–T229A–L 3,4′ –Smt3 fusion protein was expressed in a soluble manner and finally purified with the highest purity using size exclusion chromatography, which was suitable for further protein crystallization.
    Print ISSN: 2352-3409
    Topics: Biology
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  • 2
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    Analysis of the energy consumption of private households in Germany using multi-level cross-impact balance approach - Data (2016)
    Elsevier
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    Publication Date: 2016-12-29
    Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Stefan Vögele, Patrick Hansen, Witold-Roger Poganietz, Sigrid Prehofer, Wolfgang Weimer-Jehle Many studies stress the needs of interdependence analysis under the special conditions of multidisciplinary systems that include social systems. This applies, in particular, to scenarios on future energy demand and supply. Using the example of the residential sector in Germany we provide information on factors and their possible outcomes taking multidisciplinary aspects into account. In addition, futures are presented reflecting consistent combinations of the outcomes of the selected factors. These futures can be used as storylines for further analyses (see (S. Vögele, P. Hansen, W-R. Poganietz, S. Prehofer, W. Weimer-Jehle) [1] ).
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    Topics: Biology
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  • 3
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    Data for the size of cholesterol-fat micelles as a function of bile salt concentration and the physico-chemical properties of six liquid experimental pine-derived phytosterol formulations in a cholesterol-containing artificial intestine fluid (2016)
    Elsevier
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    Publication Date: 2016-12-28
    Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Jinsoo Yi, Tine A. Knudsen, Anne-Louise Nielsen, Lars Duelund, Morten Christensen, Pablo Hervella, David Needham, Ole G. Mouritsen The data in this paper are additional information to the research article entiltled “Inhibition of cholesterol transport in an intestine cell model by pine-derived phytosterols” (Yi et al.,2016) [1] . The data derived from the measurement on six liquid formulations of commercial pine-derived phytosterol (CPP) by dynamic light scattering. The data cover micelle size and the zeta-potential for formulations with cholesterol including monoglyceride, oleic acid, and bile salt. The data demonstrate the critical effect of the bile salt concentration on the size of cholesterol-digested fat micelles.
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    Topics: Biology
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  • 4
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    Driver behaviour data linked with vehicle, weather, road surface, and daylight data (2016)
    Elsevier
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    Publication Date: 2016-12-28
    Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Odd André Hjelkrem, Eirin Olaussen Ryeng In this data set, vehicle observations have been linked to data containing weather and road surface conditions. A total of 311 908 observations are collected and classified in categories of precipitation type, road status information, and daylight condition. The data is collected for a long period of time, so that several different weather situations are present, ranging from dry summer to adverse winter weather conditions.
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    Topics: Biology
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  • 5
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    Data on green tea flavor determinantes as affected by cultivars and manufacturing processes (2016)
    Elsevier
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    Publication Date: 2016-12-28
    Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Zhuo-Xiao Han, Mohammad M. Rana, Guo-Feng Liu, Ming-Jun Gao, Da-Xiang Li, Fu-Guang Wu, Xin-Bao Li, Xiao-Chun Wan, Shu Wei This paper presents data related to an article entitled “Green tea flavor determinants and their changes over manufacturing processes” (Han et al., 2016) [1]. Green tea samples were prepared with steaming and pan firing treatments from the tender leaves of tea cultivars ‘Bai-Sang Cha’ (‘BAS’) and ‘Fuding-Dabai Cha’ (‘FUD’). Aroma compounds from the tea infusions were detected and quantified using HS-SPME coupled with GC/MS. Sensory evaluation was also made for characteristic tea flavor. The data shows the abundances of the detected aroma compounds, their threshold values and odor characteristics in the two differently processed tea samples as well as two different cultivars.
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    Topics: Biology
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  • 6
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    The profile of Cyr61 expression data correlate to the skin inflammation in psoriasis (2016)
    Elsevier
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    Publication Date: 2016-12-28
    Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Pinru Wu, Gang Ma, Ningli Li The data presented in this article are related to the research article entitled “Cyr61/CCN1 is involved in the pathogenesis of psoriasis vulgaris via promoting IL-8 production by keratinocytes in a JNK/NF-κB pathway” (Pinru Wu, Gang Ma, Xianjin Zhu, Ting Gu, Jie Zhang, Yue Sun, Hui Xu, Rongfen Huo, Beiqing Wang, Baihua Shen, Xiangdong Chen, Ningli Li, 2016) [1] . Cysteine-rich 61 (Cyr61/CCN1), a secreted extracellular matrix protein, is a novel proinflammatory factor. In this dataset skin samples from normal donors and psoriasis vulgaris patients were examined the expression of Cyr61 and IL-8 using immunohistochemistry. IMQ-induced psoriasis-like mice were treated with anti-Cyr61monoclonal antibodies (mAb).
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    Topics: Biology
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  • 7
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    Data set on a study of gene expression in peripheral samples to identify biomarkers of severity of allergic and nonallergic asthma (2016)
    Elsevier
    Details
    Publication Date: 2016-12-28
    Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Selene Baos, David Calzada, Lucía Cremades, Joaquín Sastre, Joaquín Quiralte, Fernando Florido, Carlos Lahoz, Blanca Cárdaba This article contains information related to the research article entitled “Biomarkers associated with disease severity in allergic and nonallergic asthma” (S. Baos, D. Calzada, L. Cremades, J. Sastre, J. Quiralte, F. Florido, C. Lahoz, B. Cárdaba, In press). Specifically, the clinical criteria stablished for selecting the study population ( n =104 subjects) are described. Moreover, this article describes the criteria for selecting the 94 genes to be analyzed in PBMCs (peripheral blood mononuclear cells), it is provided a description of these genes and a Table with the genes most differentially expressed by clinical phenotypes and, finally it is detailed the experimental methodology followed for studying the protein expression of MSR1 (macrophage scavenger receptor 1), one of the genes evaluated in the research.
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    Topics: Biology
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  • 8
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    Localization of muscarinic acetylcholine receptor 2 to the intestinal crypt stem cell compartment (2016)
    Elsevier
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    Publication Date: 2016-12-27
    Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Eleanor D. Muise, Neeru Gandotra, John J. Tackett, Michaela C. Bamdad, Robert A. Cowles The data presented in this article are related to the research article entitled “Distribution of muscarinic acetylcholine receptor subtypes in the murine small intestine” (E.D. Muise, N. Gandotra, J.J. Tackett, M.C. Bamdad, R.A. Cowles, 2016) [1] . We recently demonstrated that neuronal serotonin stimulates intestinal crypt cell division, and induces villus growth and crypt depth (E.R. Gross, M.D. Gershon, K.G. Margolis, Z.V. Gertsberg, Z. Li, R.A. Cowles, 2012; M.D. Gershon, 2013) [2,3] . Scopolamine, a nonspecific muscarinic receptor antagonist, inhibited serotonin-induced intestinal mucosal growth [2] . Here we provide data regarding the localization of muscarinic acetylcholine receptor 2 to the intestinal crypt stem cell compartment.
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    Topics: Biology
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  • 9
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    Data for β-lactoglobulin conformational analysis after (-)-epigallocatechin gallate and metal ions binding (2016)
    Elsevier
    Details
    Publication Date: 2016-12-25
    Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Liangliang Zhang, Indra Dev Sahu, Man Xu, Yongmei Wang, Xinyu Hu This data article contains complementary results related to the paper “Effect of metal ions on the binding reaction of (-)-epigallocatechin gallate to β -lactoglobulin” (Zhang et al., 2017) [1] . Data was obtained by circular dichroism (CD) spectroscopy to investigate potential β -lactoglobulin ( β -Lg) conformational changes with different concentrations of EGCg and Cu 2+ or Al 3+ added to β -Lg. 500 µL of the 25 µM β -Lg solution containing EGCg (25 µM) or metal ions (0–500 µM) were measured, and the spectra were recorded. CD spectroscopy data present in this article indicated that the β -Lg-Cu, β -Lg-Al and β -Lg-EGCg interaction resulted in unfolding of the secondary structure of β -Lg.
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    Topics: Biology
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  • 10
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    Inflammatory and mitochondrial gene expression data in GPER-deficient cardiomyocytes from male and female mice (2016)
    Elsevier
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    Publication Date: 2016-12-24
    Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Hao Wang, Xuming Sun, Jeff Chou, Marina Lin, Carlos M. Ferrario, Gisele Zapata-Sudo, Leanne Groban We previously showed that cardiomyocyte-specific G protein-coupled estrogen receptor (GPER) gene deletion leads to sex-specific adverse effects on cardiac structure and function; alterations which may be due to distinct differences in mitochondrial and inflammatory processes between sexes. Here, we provide the results of Gene Set Enrichment Analysis (GSEA) based on the DNA microarray data from GPER-knockout versus GPER-intact (intact) cardiomyocytes. This article contains complete data on the mitochondrial and inflammatory response-related gene expression changes that were significant in GPER knockout versus intact cardiomyocytes from adult male and female mice. The data are supplemental to our original research article “Cardiomyocyte-specific deletion of the G protein-coupled estrogen receptor (GPER) leads to left ventricular dysfunction and adverse remodeling: a sex-specific gene profiling” (Wang et al., 2016) [1] . Data have been deposited to the Gene Expression Omnibus (GEO) database repository with the dataset identifier GSE86843 .
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    Topics: Biology
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