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Assessment of thoracic aortic conformational changes by four-dimensional computed tomography angiography in patients with chronic aortic dissection type b

  • Vascular-Interventional
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Abstract

To characterize the heartbeat-related distension of dissected and non-dissected thoracic aortic segments in chronic aortic dissection type b (CADB) ECG-gated computed tomography angiography was performed in ten CADB patients. For 20 time points of the R–R interval, multiplanar reformations were taken at non-dissected (A, B) and dissected (C) aorta: ascending aorta (A), aortic vertex (B), 10 cm distal to left subclavian (Ct, true channel; Cf, false channel). Relative amplitudes of aortic area and major and minor axis diameter changes were quantified. Area amplitudes were 12.9 ± 3.7%, 11.4 ± 1.8%, 16.5 ± 5.9% and 10.5 ± 5.7% at A, B, Ct and Cf, respectively. Area amplitudes were significantly greater at Ct than at Cf and B (p < 0.05). Major axis diameter amplitudes were 7.7 ± 1.9%, 6.2 ± 1.3%, 5.9 ± 2.0% and 6.1 ± 3.6% at A, B, Ct and Cf, respectively. There were no differences in major axis diameter amplitudes. Minor axis diameter amplitudes were 6.7 ± 2.1%, 8.4 ± 1.9%, 12.7 ± 6.3% and 6.0 ± 2.2% at A, B, Ct and Cf, respectively. Minor axis diameter amplitudes were significantly the greatest at Ct (p < 0.05). In CADB, the heartbeat-related distension of aortic area and diameter is evenly distributed over the non-dissected aortic arch. As a result from different blood flow properties, there are significantly greater conformational changes in the true channel of the dissected aorta.

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Authors and Affiliations

  1. Department of Radiology, German Cancer Research Center, Im Neuenheimer Feld 280, 69120, Heidelberg, Germany

    Tim F. Weber, Maria-Katharina Ganten & Hendrik von Tengg-Kobligk

  2. Department of Radiology, University of Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany

    Tim F. Weber & Hans-Ulrich Kauczor

  3. Department of Vascular and Endovascular Surgery, University of Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany

    Dittmar Böckler & Philipp Geisbüsch

  4. Department of Biostatistics, German Cancer Research Center, Im Neuenheimer Feld 280, 69120, Heidelberg, Germany

    Annette Kopp-Schneider

  5. Department of Radiology, Ohio State University, 657 Means Hall, 1654 Upham Dr, Columbus, OH, 43210, USA

    Hendrik von Tengg-Kobligk

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  1. Tim F. Weber
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  2. Maria-Katharina Ganten
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  6. Hans-Ulrich Kauczor
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Correspondence to Tim F. Weber.

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Tim F. Weber and Maria-Katharina Ganten contributed equally

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Weber, T.F., Ganten, MK., Böckler, D. et al. Assessment of thoracic aortic conformational changes by four-dimensional computed tomography angiography in patients with chronic aortic dissection type b. Eur Radiol 19, 245–253 (2009). https://doi.org/10.1007/s00330-008-1103-x

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  • DOI: https://doi.org/10.1007/s00330-008-1103-x

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