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Expanding the Diversity of Mycobacteriophages: Insights into Genome Architecture and Evolution

Figure 9

MPME1 insertion in mycobacteriophage Hope.

A. Alignment of the four closely related phages in Cluster G reveals insertions of MPME elements in BPs, Hope, and Halo. Hope contains an MPME1 insertion at a new site corresponding to Angel 56. B. Comparison of the Hope and Angel sequences reveals the pre-integration site; left and right inverted repeats (IR-L and IR-R) are shown in bold type. At the left end there is the presence of an atypical 6 bp insertion (shown in turquoise) between IR-L of MPME1 and the target.

Figure 9

doi: https://doi.org/10.1371/journal.pone.0016329.g009