Role of Prox1 in the Transforming Ascending Thin Limb of Henle's Loop during Mouse Kidney Development
Fig 8
Osmolality and Prox1 expression.
(A) Urine osmolalities were measured in mice at postnatal days 1, 4, 7, 14, 21, 28, and 56 on ad libitum fluid intake. Within 1 week after birth, urine osmolality was no more than 500 mOsmol/kg H2O; it began to increase from day 14, reaching peak levels at days 28 and 56. Each bar represents the mean of three independent experiments; error lines are SD. (B) At all developmental stages, Prox1 expression correlated closely with urine osmolality. R2 = 0.8870; P = 0.0015