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Conditioned Medium from Hypoxic Bone Marrow-Derived Mesenchymal Stem Cells Enhances Wound Healing in Mice

Figure 8

Collagen I and collagen III synthesis analysis.

(A). Evaluation of relative collagen I, collagen III mRNA expression. (B) Staining of collagen I and collagen III in scars treated with vehicle control, norCM or BM-MSC hypoCM. Scale bar, 100 µm (400×). Data are expressed as the mean±the SEM; *p<0.05 compared with day 20. #p< 0.05 compared with the vehicle control or the norCM group at day 40.

Figure 8

doi: https://doi.org/10.1371/journal.pone.0096161.g008