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Role of Prox1 in the Transforming Ascending Thin Limb of Henle's Loop during Mouse Kidney Development

Fig 6

Cells undergoing apoptosis in the Prox1- and NKCC2-positive TAL of the developing mouse kidney.

(A-O) Triple immunofluorescence staining for Prox1 (red), NKCC2 (white) and TUNEL (green) in the renal papilla from 7-day-old pups. Arrows indicate TUNEL-positive nuclei that did not co-localize with Prox1. Blue counterstain: DAPI. Scale bars: 20 μm. (P) Cells undergoing apoptosis are expressed as a percentage of the Prox1-positive TAL cells. Values are means ± SD.

Fig 6

doi: https://doi.org/10.1371/journal.pone.0127429.g006