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Zinc Supplementation Inhibits Complement Activation in Age-Related Macular Degeneration

Figure 5

The effect of zinc on the hemolytic activity of human serum and on the membrane attack complex (MAC) deposition on retinal pigment epithelial (RPE) cells.

(A) Zinc sulphate inhibits the lysis of rabbit erythrocytes in a dose-dependent manner. (B–C) the amount of MAC deposited on RPE cells exposed to oxidative stress can be reduced in a dose dependent manner by zinc. *p<0.05 and ***p<0.001.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0112682.g005