Alpha Lipoic Acid Attenuates Radiation-Induced Thyroid Injury in Rats
Figure 5
TGF-ß1 immunohistochemical staining of cross sections of rat thyroid gland tissue.
The immunohistochemical localization of TGF-ß1 appears as dark-brown staining. TGF-ß1 expression was more intense in the follicular epithelium of the irradiated rats (RT) (thyrocytes strongly express TGF-ß1). The signals were stronger on day 7 than day 4. TGF-ß1 expression was less intense in the ALA group compared to the RT group. CTL, control. RT, irradiated. ALA, ALA only. ALA + RT, received ALA before irradiation. Scale bar, 100 µm.