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MicroRNA expression profiles in molecular subtypes of clear-cell renal cell carcinoma are associated with clinical outcome and repression of specific mRNA targets

Fig 4

Scatterplot illustrating the correlation between subtype-specific miRNA expression (Log2(FC)) and HR for OS (Leuven dataset, n = 95).

There was a strong correlation throughout the dataset, with a Pearson coefficient of -0.54 (332 degrees of freedom). Hazard ratio for OS is plotted on a log2-scale for graphical reasons; the regression line was fitted on the original data. HR = hazard ratio; OS = overall survival; FC = fold change.

Fig 4

doi: https://doi.org/10.1371/journal.pone.0238809.g004