Efficacy of a Metalloproteinase Inhibitor in Spinal Cord Injured Dogs
Figure 4
T2-weighted magnetic resonance images in dogs with spinal cord injuries from intervertebral disk herniation.
In 1 dog (A, B) that was non-ambulatory with intact pelvic limb movement and sensation, there was focal ventrolateral spinal cord compression at the T12-T13 vertebral articulation without spinal cord signal change. A second dog (C, D) with paraplegia and absent pelvic limb deep nociception had compression at the T12-T13 vertebral articulation. There was extensive spinal cord T2-weighted hyperintensity (white arrows) visible on the sagittal image (C), suggestive of processes seen in contusion injuries such as edema, necrosis, hemorrhage, or cellular infiltrates. The transverse image (D, level of T13 vertebral body) indicated that T2-weighted hyperintensity was predominantly localized to the gray matter.