Regeneration of the Exocrine Pancreas Is Delayed in Telomere-Dysfunctional Mice
Figure 4
Block of proliferation in telomere-dysfunctional mice.
(A) Representative pictures of Ki-67 staining of pancreata of indicated genotype and time point after pancreatitis (Ki-67 positive nuclei are stained black; size bar = 500 µm). (B) Quantification of Ki-67 positive cells of mTerc+/+ and G3 mTerc−/− mice at indicated time points after pancreatitis induction. (C) Analysis of cell cycle proteins in pancreata of mTerc+/+ and G3 mTerc−/− mice before and 7 d after pancreatitis induction (pH3 = phospho Histone 3 Serine 10).