Genetics Meets Metabolomics: A Genome-Wide Association Study of Metabolite Profiles in Human Serum
Figure 4
Boxplots of the strongest associations of metabolite concentration ratios with polymorphisms in the FADS1 (A; p = 2.4×10−22), SCAD (B; p = 9.3×10−17), and MCAD (C; p = 7.6×10−17) genes (see legend to Figure 3 for details).
The metabolic efficiencies of the reactions that are catalyzed by these three enzymes differ considerably between individuals of different genotype.