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Combinatorial Polymer Electrospun Matrices Promote Physiologically-Relevant Cardiomyogenic Stem Cell Differentiation

Figure 4

Effect of mechanical properties on EB differentiation.

(a) SEM images of (a) high fiber density and (b) low fiber density scaffolds. (c) Wet modulus of PCL and 4%PEG-86%PCL-10%CPCL. * p<0.05 versus high density fibers. (d) α-MHC gene expression is enhanced on low versus high density fiber scaffolds, indicating improved differentiation. * p<0.05 versus high density PCL **p<0.0005 versus high density 4%PEG-86%PCL-10%CPCL.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0028935.g004