Methylobacterium Genome Sequences: A Reference Blueprint to Investigate Microbial Metabolism of C1 Compounds from Natural and Industrial Sources
Figure 4
Clustering and conservation of serine cycle and other genes important for methylotrophic metabolism in sequenced methylotrophic bacteria.
Sequences were retreived from Genbank and visualized using CLC Sequence Viewer 5 (www.clcbio.com). Chromosome sequence positions are indicated, as well as the percent identity at the protein level with Methylobacterium prototypes (nd: not detectable). Formate tetrahydrofolate ligase/formyl-tetrahydrofolate synthetase (ftfL, black); serine hydroxymethyltransferase (glyA, pink); serine glyxoylate aminotransferase (sga, yellow); hydroxypyruvate reductase (hprA, red); glycerate kinase (gck, purple); phosphoenolpyruvate carboxylase (ppc, orange); malyl-CoA lyase/β-methylmalyl-CoA lyase (mcl, dark green); malate thiokinase (mtkA/mtkB, light green); NAD(P)-dependent methylene-tetrahydromethanopterin/methylene-tetrahydrofolate dehydrogenase (mtdA, dark blue); methenyl tetrahydrofolate cyclohydrolase (fch, light blue); bifunctional methylene-tetrahydrofolate dehydrogenase/methenyl-tetrahydrofolate cyclohydrolase (folD, grey); transcriptional regulator (pale green); other (white); tRNA (black rectangles).