Alpha Lipoic Acid Attenuates Radiation-Induced Thyroid Injury in Rats
Figure 3
The percentage of three size-classes of the follicles.
Follicles were divided into three categories based on their size: small (18–30 µm in diameter), medium (31–60 µm), and large (>60 µm). In the irradiated rats (RT), there occurred a statistically significant increase in the quantity of small and medium follicles compared to in the control and ALA-treated irradiated rats (ALA + RT). Small follicles were more common in the irradiated rats (RT), and greater numbers were observed on day 7 post-radiation compared to day 4. Small follicles in ALA-treated irradiated rats (ALA + RT) were less frequent than in irradiated rats (RT). (CTL, control; ALA, ALA only; RT-D4, Irradiated rats on day 4; RT-D7, Irradiated rats on day 7; ALA + RT-D4, ALA-irradiated rats on day 4; ALA + RT-D7, ALA-irradiated rats on day 7) (*P<0.05, §P<0.01).