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Receptor Activator of NF-kB (RANK) Expression in Primary Tumors Associates with Bone Metastasis Occurrence in Breast Cancer Patients

Figure 3

Immunohistochemical results in 93 breast cancers.

Image A: RANK positive breast cancer. The normal glandular epithelium is negative (N) confirming the RANK protein overexpression of the tumor tissue. Image B: RANK negative breast cancer (TC). Tissue-associated macrophages (M) are positive for RANK staining and are used as internal positive controls. Original magnification A,B 200×.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0019234.g003