Trichloroethylene-Induced Gene Expression and DNA Methylation Changes in B6C3F1 Mouse Liver
Figure 2
Selected gene expression changes in the liver of mice exposed to different doses of TCE (0, 100, 500 and 1000 mg/kg b.w.) (n = 3).
A) qPCR analysis of selected mRNA expression changes in mouse liver. B) Western analysis of Dnmt1 protein expression levels. Fold expression at each dose was calculated against the nonexposed samples (TCE dose level at 0 mg/kg). *, p<0.05; **, p<0.01. ***, p<0.001.