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Epstein-Barr virus antibodies in serum and DNA load in saliva are not associated with radiological or clinical disease activity in patients with early multiple sclerosis

Fig 1

EBV antibodies in serum and DNA load in saliva in healthy controls and patients with early MS.

Levels of Immunoglobulin (Ig)G antibodies to Epstein-Barr nuclear antigen-1 (EBNA-1, A) and viral capsid antigen (VCA, B) in serum of healthy controls (HC, n = 57) and patients with clinically isolated syndrome (CIS) and early relapsing-remitting MS (RRMS, n = 100). (C) EBV DNA copy number in saliva of healthy controls (n = 47) and patients with CIS/early RRMS (n = 48). The horizontal lines indicate the median (median EBV DNA load was 0 in HC and CIS/early RRMS).

Fig 1

doi: https://doi.org/10.1371/journal.pone.0175279.g001