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Alpha Lipoic Acid Attenuates Radiation-Induced Thyroid Injury in Rats

Figure 1

Representative photomicrographs of thyroid histology in the control, ALA, RT and ALA + RT groups after radiation.

Hematoxylin-eosin staining was performed on cross sections of the thyroid glands. Irregular-sized, smaller follicles than in the control group are noted in addition to inflammatory cell infiltration in the interfollicular area in the irradiated thyroid. Follicles of the ALA + RT group are more normal in size than those of the irradiated rats. CTL, control. RT, irradiated. ALA, ALA only. ALA + RT, received ALA before irradiation. Scale bar, 100 µm.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0112253.g001