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Effect of short-term hindlimb immobilization on skeletal muscle atrophy and the transcriptome in a low compared with high responder to endurance training model

Fig 1

Phenotype data showing (A) running distance after an 8-wk treadmill training program, (B) myosin heavy chain (Myh) transcript expression, (C) soleus muscle mass and (D) plantaris muscle mass, (E) soleus muscle protein synthesis and (F) plantaris muscle protein synthesis, in hindlimb immobilization (3 d; HI) and control (CTRL) groups of selectively bred low- and high responders to endurance training (LRT vs. HRT). Boxes indicate the interquartile range (25%-75%) with the horizontal bar within each box indicating the median. The whiskers show the minimum and maximum values. P-values vs. breeding line-matched control (n = 6/group).

Fig 1

doi: https://doi.org/10.1371/journal.pone.0261723.g001