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Diagnostic and Prognostic Value of SHOX2 and SEPT9 DNA Methylation and Cytology in Benign, Paramalignant and Malignant Pleural Effusions

Figure 1

SHOX2 and SEPT9 DNA methylation in PEs from cancer patients and patients with benign diseases.

Methylation values of SHOX2 and SEPT9 in PEs from patients with cancer (cases) and patients with benign diseases (controls) determined by quantitative real-time PCR. The p-values refer to a Students t-test. A methylation cut-off was used to classify patient samples as SHOX2 positive (above the cut-off).

Figure 1

doi: https://doi.org/10.1371/journal.pone.0084225.g001