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Das Tubenepithel in Korrelation zu histologischen Befunden an Endometrium und Ovar

Histological correlations between the tubal epithelium, endometrium and ovaries

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Summary

From surgical specimens (panhysterosalpingo-oophorectomies) we compared the height and degree of epithelial proliferation in the Fallopian tube with that in the associated endometrium, and correlated these results with changes found in the ovaries. The degree of hyperplasia of the tubal epithelium proved to be similar to that of the endometrium. A like increase in tubal hyperplasia was associated with changes in the ovaries which indicated increased hormonal activity. Only in rare instances of severe salpingitis did the tubal epithelium proliferate independent of ovarian or endometrial changes. The proliferation of the tubal epithelium in its extent and histology resembles the hyperplasia occurring at the same time in the endometrium. Our findings strongly suggest that the atypical epithelial proliferation in both target organs is induced by a continuous, unopposed secretion of estrogen.

Zusammenfassung

An Hand eines größeren Operationsgutes wurden Tuben, Ovarien und Endometrium histologisch auf Höhe und Ausmaß der Epithelproliferation in Tube und Endometrium sowie Vorkommen und Art begleitender Ovarveränderungen untersucht. Dabei ergab sich eine mit der Intensität der Endometriumhyperplasie parallel ansteigende Proliferation des Tubenepithels. Ein ähnliches Ansteigen war bei Korrelation der Tubenbefunde mit hormonell aktiven Veränderungen des Ovars festzustellen. Unabhängig von Endometrium-und Ovarbefunden proliferierte das Tubenepithel nur ausnahmsweise bei schwerer Salpingitis. Die Proliferation des Tubenepithels weist somit in Ausmaß und Struktur Analogien auf zur gleichzeitigen Proliferation des Endometriumepithels. Diese Befunde sprechen für die Auslösung der atypischen Proliferation an beiden Erfolgsorganen durch kontinuierliche ungehemmte Oestrogenstimulationen.

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Dallenbach-Hellweg, G., Niehoff, B. Das Tubenepithel in Korrelation zu histologischen Befunden an Endometrium und Ovar. Virchows Arch. Abt. A Path. Anat. 354, 66–79 (1971). https://doi.org/10.1007/BF00544108

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  • DOI: https://doi.org/10.1007/BF00544108

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