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Randomized clinical trial of intraocular silicone vs. gas in the management of complicated retinal detachment and vitreous hemorrhage

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Abstract

We performed a prospective randomized clinical study to compare intravitreal silicone oil vs. gas (20% C3F8 or 30% C4F8) in the management of complicated retinal detachments and vitreous hemorrhage. Despite similar anatomic and visual results, the gas-treated group had significantly more instances of vitreous hemorrhage, late elevated intraocular pressure, and localized retinal detachment as postoperative complications than those receiving oil injections (P<.05). Silicone oil injections containing less than 3.0ml contributed significantly to postoperative detachments (P<.05).

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Authors and Affiliations

  1. Department of Ophthalmology, Eye and Ear Infirmary, University of Illinois College of Medicine at Chicago, 1855 W. Taylor St., 60612, Chicago, IL, USA

    Gholam A. Peyman, Grace W. Kao & Luis R. de Corral

Authors
  1. Gholam A. Peyman
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  2. Grace W. Kao
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  3. Luis R. de Corral
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Supported in part by a grant from Research to Prevent Blindness, Inc, New York City.

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Peyman, G.A., Kao, G.W. & de Corral, L.R. Randomized clinical trial of intraocular silicone vs. gas in the management of complicated retinal detachment and vitreous hemorrhage. Int Ophthalmol 10, 221–234 (1987). https://doi.org/10.1007/BF00155629

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  • DOI: https://doi.org/10.1007/BF00155629

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