ISSN:
1434-9949
Keywords:
Etidronate
;
Rheumatoid Arthritis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Diphosphonates reduce the rate of bone turnover. They have additional pharmacological properties improving adjuvant arthritis in rats and lowering ESR in this condition. We have evaluated etidronate disodium, a diphosphonate commonly prescribed in the United Kingdom for Paget's disease in patients with rheumatoid arthritis. Apart from an early improvement in articular index, perhaps reflecting anti-inflammatory activity, no significant change occurred in clinical variables or in laboratory indices of ‘secondline’ action at a dose of 5 mg/kg/day.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02284063
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