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  • 5-methyltetrahydrohomofolate  (1)
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  • 1
    Electronic Resource
    Electronic Resource
    5-methyltetrahydrohomofolate (1987)
    Springer
    Investigational new drugs 5 (1987), S. 215-218 
    Details
    ISSN: 1573-0646
    Keywords: 5-methyltetrahydrohomofolate ; antimetabolite ; antifolate ; pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Abstract 5-methyltetrahydrohomofolate was developed in the 1970's as an antifolate with the potential to overcome methotrexate resistance. This review summarizes the preclinical and clinical data which have accumulated to date. It is concluded that more recent, better characterized antifolates offer greater potential in achieving the goals for which this drug was introduced.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00175290
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