Publication Date:
2017-01-24
Description:
Mechanotransductive cascade of Myo-II-dependent mesoderm and endoderm invaginations in embryo gastrulation Nature Communications, Published online: 23 January 2017; doi:10.1038/ncomms13883 Mechanical signals regulate tissue differentiation but how this triggers downstream biochemical signals is unclear. Here, the authors place micro-magnets in the Drosophila embryonic epithelia and show this triggers apical pulsations, in turn stabilizing Myosin-II, resulting in mesoderm invagination.
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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