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  • 1980-1984  (1)
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    Electronic Resource
    Electronic Resource
    Basic defect in the expression of adenosine deaminase in ADA -SCID disease (1983)
    Springer
    Human genetics 〈Berlin〉 63 (1983), S. 121-125 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A specific competitive radioimmunoassay (RIA) was employed to quantify human adenosine deaminase molecules produced in human-Chinese hamster somatic cell hybrids. Studies on a set of hybrids in which the normal and aberrant expressions of adenosine deaminase (assigned earlier to human chromosome 20) were segregating, have demonstrated that in the patient with ADA -SCID disease reported by Herbschleb-Voogt et al (1981a), the deficiency of ADA activity was associated with a comparable deficiency of adenosine deaminase specific immuno-crossreacting material (ADA-CRM).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00291530
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