Description: Highlights • Investigation on PFAS in seafood was conducted for the first time in North Africa. • Long-chain PFAS were predominant in seafood from the study area. • Among seafood, crustaceans exhibited the highest concentrations of PFAS. • PFOS was the predominant PFAS compound in most marine species. • Human health risks for PFAS exposure via seafood consumption was minimal. Abstract Despite the ubiquity of per- and polyfluorinated alkyl substances (PFAS) in all environmental compartments, little is known about the pollution they cause on the African continent, neither on levels, nor effects. Here we examined the occurrence and levels of 21 legacy and emerging PFAS in 9 marine species (3 fish, 2 crustaceans and 4 mollusks) collected from Bizerte lagoon, Northern Tunisia. Furthermore, assessment of potential human health risks through consumption of contaminated seafood was examined. This is the first study assessing PFAS in Mediterranean coastal areas of North Africa. Twelve out of the 21 targeted PFAS were detected, evidencing the occurrence of PFAS in seafood from North Africa, albeit at low levels. The Ʃ21PFAS concentrations in all seafood samples ranged from 0.202 ng g−1 dry weight (dw) to 2.89 ng g−1 dw, with a mean value of 1.10 ± 0.89 ng g−1 dw. The profiles of PFAS varied significantly among different species, which might be related to their different trophic level, protein content, feeding behaviour and metabolism. Generally, current exposure to PFAS through seafood consumption indicates that it should not be of concern to the local consumers, at least for those PFAS for which information is available.

Description: Plastic, paper and cardboard are widely used as food contact materials (FCMs), due to its numerous favourable characteristics. However, they are usually coated with hazardous substances, such as per- and polyfluorinated alkyl substances (PFASs). PFASs, with its functional properties of oil- and water-repellency, can migrate from FCMs into the food and cause potential risk to human health. There are also increasing concerns about the harm that FCMs can cause to the environment. These concerns include accumulation of non-degradable plastics in the environment, generation of microplastics (MPs) and nanoplastics, and release of PFASs from FCMs. While many reviews have been conducted on PFASs in the environment, including their occurrence, fate, toxicity, biodegradation, migration in ecosystems and remediation technologies, a systematic review of PFASs in FCMs and MPs is currently lacking. In addition, our knowledge of the PFAS sorption processes on MPs is rather limited, and in particular their desorption processes. Thus, this review aims to (1) review the presence of various classes of PFASs in FCMs and their migration into food, (2) review the PFASs in MPs and summarize the sorption mechanisms, and factors that influence their sorption behaviour on MPs in the aquatic environment, and (3) identify the current research gaps and future research directions to predict the risks associated with the presence and sorption of PFASs in FCMs and MPs.