In:
European Thyroid Journal, Bioscientifica, Vol. 10, No. 6 ( 2021), p. 476-485
Abstract:
〈 b 〉 〈 i 〉 Introduction: 〈 /i 〉 〈 /b 〉 Numbers of thyroidectomies and awareness of postoperative quality measures have both increased. Potential sex-specific variations in clinical outcomes of patients undergoing thyroidectomy are controversial. 〈 b 〉 〈 i 〉 Objective: 〈 /i 〉 〈 /b 〉 The aim of this study was to investigate sex-specific differences in outcomes following thyroidectomy. 〈 b 〉 〈 i 〉 Methods: 〈 /i 〉 〈 /b 〉 This is a population-based cohort study of all adult patients undergoing either hemi- or total thyroidectomy in Switzerland from 2011 to 2015. The primary outcome was all-cause 30-day readmission rate. The main secondary outcomes were intensive care unit (ICU) admission, surgical re-intervention, in-hospital mortality, length of hospital stay (LOS), postoperative calcium disorder, vocal cord paresis, and hematoma. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 Of 16,776 patients undergoing thyroidectomy, the majority of patients undergoing thyroidectomy were female (79%), with a median age of 52 (IQR 42–64) years. Within 30 days after the surgery, male patients had significantly higher rates of hospital readmission (adjusted risk ratio [RR] 1.38; 95% confidence interval [95% CI] 1.11–1.72, 〈 i 〉 p 〈 /i 〉 = 0.008) and higher risks for postoperative ICU admission (RR 1.25; 95% CI, 1.09–1.44, 〈 i 〉 p 〈 /i 〉 = 0.003) than female patients. There were no significant differences among sexes in the LOS, rates of surgical re-interventions, or in-hospital mortality. While postoperative calcium disorders due to hypoparathyroidism were less prevalent among male patients (RR 0.63; 95% CI, 0.54–0.72, 〈 i 〉 p 〈 /i 〉 & #x3c; 0.001), a 2-fold higher incidence rate of postoperative hematoma was observed (RR 1.93, 95% CI, 1.51–2.46, 〈 i 〉 p 〈 /i 〉 & #x3c; 0.001). 〈 b 〉 〈 i 〉 Conclusions: 〈 /i 〉 〈 /b 〉 Male patients undergoing thyroidectomy have higher 30-day hospital readmission and ICU admission rates. Following surgery, male patients revealed higher rates of neck hematoma, while hypocalcemia was more frequent among female patients.
Type of Medium:
Online Resource
ISSN:
2235-0640
,
2235-0802
Language:
English
Publisher:
Bioscientifica
Publication Date:
2021
detail.hit.zdb_id:
2659767-6
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