GLORIA

GEOMAR Library Ocean Research Information Access

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
Document type
Language
  • 1
    Online Resource
    Online Resource
    Oxford :Taylor & Francis Group,
    Keywords: Neural circuitry. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (257 pages)
    Edition: 1st ed.
    ISBN: 9781317781370
    DDC: 006.3
    Language: English
    Note: Cover -- Half Title -- Title Page -- Copyright Page -- Dedication -- Table of Contents -- Preface and Acknowledgements -- Part I CALM: Categorizing And Learning Module -- 1 Introduction -- 1.1 The importance of learning -- 1.2 Some problems with learning neural networks -- 1.3 Structural constraints -- 1.4 Functional constraints: attention and learning -- 1.5 Implementation of the constraints -- 2 Description of CALM -- 2.1 Structure of CALM -- 2.2 Functioning of CALM -- 3 Simulation studies of performance and self-organization in CALM -- 3.1 Simulation with CALM -- 3.2 Convergence time and discrimination time -- 3.3 Discrimination and clustering -- 3.4 Illustration: learning the EXOR -- 3.5 Topological self-organization in CALM modules -- Part II Application -- 4 Psychological models -- 4.1 Learning the word-superiority effect for letter recognition -- 4.2 Modelling human memory -- 5 Pattern recognition as a practical application -- 5.1 Approaches to pattern recognition -- 5.2 Sources o f pattern variability -- 5.3 A small network that learns handwritten numerals -- 6 Genetic algorithms: modularity, learning and network design -- 6.1 A brief introduction to genetic algorithms -- 6.2 Modules as partial solutions -- 6.3 The interaction of evolution and learning -- 6.4 Genetic algorithms and neural networks -- 6.5 Designing modular networks with genetic algorithms -- Part III Revisiting Modularity -- 7 Evaluation of CALM -- 7.1 The status of CALM -- 7.2 Biological plausibility -- 7.3 Computational plausibility -- 7.4 Psychological plausibility -- 7.5 Conclusions -- Appendix A -- Appendix B1 Hardware and software for neural networks -- Appendix B2 Virtual implementations on transputer networks -- Appendix B3 Hybrid implementation: the BSP400, a dedicated multiprocessor -- Appendix B4 Physical implementation: some notes on CALM in analog hardware. , Appendix B5 Modular neurosimulators -- Bibliography -- Name index -- Subject index.
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 2
    Keywords: Testis--Growth. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (106 pages)
    Edition: 1st ed.
    ISBN: 9783642583537
    Series Statement: Advances in Anatomy, Embryology and Cell Biology Series ; v.156
    Language: English
    Note: Intro -- Advances in Embryology Anatomy and Cell Biology Vol. 156 -- The Testicular Descent in Human -- Copyright -- Preface -- Contents -- 1 Introduction -- 2 Materials and Methods -- 3 Transabdominal (Inner) Descent of Gonads - Anlage of Diaphragm and Cranial Mesonephric Ligament -- 4 Development, Shape and Fate of Gubernaculum Hunteri and Processus Vaginalis Peritonei - Own Phases of Testicular Descent -- 5 Origin of the Caudal Ligaments of the Ovary and Uterus -- 6 Summary and Conclusions -- References -- Subject Index.
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 3
    Online Resource
    Online Resource
    San Diego :Elsevier Science & Technology,
    Keywords: Molecular biology -- Mathematics. ; Biomathematics. ; Cytoskeleton -- Mathematics. ; Cells -- Morphology -- Mathematics. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (535 pages)
    Edition: 1st ed.
    ISBN: 9780080528076
    DDC: 572.8/0151
    Language: English
    Note: Front Cover -- Biomathematics: Mathematics of Biostructures and Biodynamics -- Copyright Page -- Contents -- Chapter 1. Introduction -- References -- Chapter 2. Counting, Algebra and Periodicity - the Roots of Mathematics are the Roots of Life -- 2.1 Counting and Sine -- 2.2 Three Dimensions -- Planes and Surfaces, and Surface Growth -- 2.3 The Growth of Nodal Surfaces - Molecules and Cubosomes -- References 2 -- Chapter 3. Nodal Surfaces of Tetragonal and Hexagonal Symmetry, and Rods -- 3.1 Non Cubic Surfaces -- 3.2 Tetragonal Nodal Surfaces and their Rod Structures -- 3.3 Hexagonal Nodal Surfaces and their Rod Structures -- References 3 -- Chapter 4. Nodal Surfaces, Planes, Rods and Transformations -- 4.1 Cubic Nodal Surfaces -- 4.2 Nodal Surfaces and Planes -- 4.3 Cubic Nodal Surfaces and Parallel Rods -- 4.4 Transformations of Nodal Surfaces -- References 4 -- Chapter 5. Motion in Biology -- 5.1 Background and Essential Functions -- 5.2 The Control of Shape - the Natural Exponential or cosh in 3D -- 5.3 The Gauss Distribution (GD) Function and Simple Motion -- 5.4 More Motion in 3D -- References 5 -- Chapter 6. Periodicity in Biology - Periodic Motion -- 6.1 The Hermite Function -- 6.2 Flagella- Snake and Screw Motion -- 6.3 Periodic Motion with Particles in 2D or 3D -- 6.4 Periodic Motion with Rotation of Particles in 2D -- References 6 -- Chapter 7. Finite Periodicity and the Cubosomes -- 7.1 Periodicity and the Hermite Function -- 7.2 Cubosomes and the Circular Functions -- 7.3 Cubosomes and the GD-Function - Finite Periodicity and Symmetry P -- 7.4 Cubosomes and the GD-Function - Symmetry G -- 7.5 Cubosomes and the GD Function - Symmetry D -- 7.6 Cubosomes and the Handmade Function -- References 7 -- Chapter 8. Cubic Cell Membrane Systems/Cell Organelles and Periodically Curved Single Membranes -- 8.0 Introduction -- 8.1 Cubic Membranes. , 8.2 The Endoplasmatic Reticulum -- 8.3 Protein Crystallisation in Cubic Lipid Bilayer Phases and Cubosomes - Colloidal Dispersions of Cubic Phases -- 8.4 From a Minimal Surface Description to a Standing Wave Dynamic Model of Cubic Membranes -- 8.5 Periodical Curvature in Single Membranes -- References 8 -- Chapter 9. Cells and their Division - Motion in Muscles and in DNA -- 9.1 The Roots and Simple Cell Division -- 9.2 Cell Division with Double Membranes -- 9.3 Motion in Muscle Cells -- 9.4 RNA and DNA Modelling -- References 9 -- Chapter 10. Concentration Gradients, Filaments, Motor Proteins and again- Flagella -- 10.1 Background and Essential Functions -- 10.2 Filaments -- 10.3 Microtubulus and Axonemes -- 10.4 Motor Proteins and the Power Stroke -- 10.5 Algebraic Roots Give Curvature to Flagella -- References 10 -- Chapter 11. Transportation -- 11.1 Background - Examples of Docking and Budding with Single Plane Layers, and Other Simple Examples -- 11.2 Docking and Budding with Curved Single Layers -- 11.3 Transport Through Double Layers -- References 11 -- Chapter 12. Icosahedral Symmetry, Clathrin Structures, Spikes, Axons, the Tree, and Solitary Waves -- 12.1 The icosahedral symmetry -- 12.2 Hyperbolic Polyhedra, Long Cones, Cylinders and Catenoids -- 12.3 Cylinder Division and Cylinder Fusion - Cylinder Growth -- 12.4 Solitary Waves, Solitons and Finite Periodicity -- References 12 -- Chapter 13. Axon Membranes and Synapses - A Role of Lipid Bilayer Structure in Nerve Signals -- 13.1 The Nerve Impulse -- 13.2 At the Action Potential Region of the Membrane there is a Phase Transition in the Lipid Bilayer -- 13.3 A Model of a Phase-Transition/Electric Signal Coupling at Depolarisation and its Physiological Significance -- 13.4 Transmission of the Nerve Signal at the Terminal Membrane of the Neurons - Synaptic Transmission. , 13.5 Synchronisation of Muscle Cell Activation -- 13.6 The General Anaesthetic Effect -- 13.7 Physiological Significance of Involvement of a Lipid Bilayer Phase Transition in Nerve Signal Conduction -- References 13 -- Chapter 14. The Lung Surface Structure and Respiration -- 14.1 The Alveolar Surface -- 14.2 Lung Surfactant -- 14.3 Structure of Tubular Myelin - A Bilayer arranged as the Classical CLP-Surface -- 14.4 The Existence of a Coherent Surface Phase Lining the Alveoli -- 14.5 Respiration -- 14.6 Physiological Significance of the Existence of an Organised Surface Phase at the Alveolar Surface -- References 14 -- Chapter 15. Epilogue -- Acknowledgement -- References 15 -- Appendix 1. The Plane, the Cylinder and the Sphere -- Appendix 2. Periodicity -- Appendix 3. The Exponential Scale, the GD function, Cylinder and Sphere Fusion -- Appendix 4. The Exponential Scale, the Planes and the Natural Function, Addition and Subtraction 409 -- Appendix 5. Multiplication of Planes, Saddles and Spirals -- Appendix 6. Symmetry -- Appendix 7. The Complex Exponential, the Natural Exponential and the GD- Exponential - General Examples and Finite Periodicity -- Appendix 8. Classical Differential Geometry and the Exponential Scale -- Appendix 9. Mathematica (Contains the Mathematica scripts used for calculating the equations for the figures in this book.) -- Subject Index.
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 4
    Keywords: Hochschulschrift ; Chile Süd ; Neotektonik ; Strukturgeologie
    Type of Medium: Online Resource
    Pages: Online-Ressource (PDF-Datei: V, 73 S., 25,8 MB) , graph. Darst.
    Language: English , German
    Note: Enth. Zeitschriften-Aufsätze , Kiel, Univ., Diss., 2011
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 5
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: A μ-opioid receptor protein (μ-ORP) purified to homogeneity from bovine striatal membranes has been functionally reconstituted in liposomes with highly purified heterotrimeric guanine nucleotide regulatory proteins (G proteins). A mixture of bovine brain G proteins, predominantly GoA, was used for most of the experiments, but some experiments were performed with individual pure G proteins, GoA, GoB, Gi1, and Gi2. Low Km GTPase was stimulated up to 150% by μ-opioid receptor agonists when both μ-ORP and a G protein (either the brain G protein mixture or a single heterotrimeric G protein) were present in the liposomes. Stimulation by a selective μ-agonist was concentration dependent and was reversed by the antagonist (−)-naloxone, but not by its inactive enantiomer, (+)-naloxone. The μ selectivity of μ-ORP was demonstrated by the inability of δ and κ agonists to stimulate GTPase in this system. High-affinity μ-agonist binding was also restored by reconstitution with the brain G protein mixture and with each of the four pure Gi and Go proteins studied. The binding of μ agonists is sensitive to inhibition by GTPγS and by sodium.
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 6
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: Opioid receptors were solubilized from bovine striatal membranes with the zwitterionic detergent 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate-(CHAPS). High concentrations of NaCl (0.5–1.0 M) were necessary to ensure optimal yields, which ranged from 40 to 50% of membrane-bound receptors. This requirement was found to be specific for sodium, with only lithium able to substitute partially, as previously reported for solubilization with digitonin. Opioid antagonists, but not agonists, were able to bind to soluble receptors with high affinity. High-affinity binding of μ, δ, and κ agonists was reconstituted following polyethylene glycol precipitation and resuspension of CHAPS extract. Evidence is presented suggesting that this is the result of inclusion of receptors in liposomes. Competition and saturation studies indicate that the three opioid receptor types retain their selectivity and that they exist in the reconstituted CHAPS extract in a ratio (50:15:35) identical to that in the membranes. In reconstituted CHAPS extract, as in membranes, μ-agonist binding was found to be coupled to a guanine nucleotide binding protein (G protein), as demonstrated by the sensitivity of [3H][d-Ala2, N-methyl-Phe4,Gly5-ol]-enkephalin ([3H]DAGO) binding to guanosine 5′-O-(thiotriphosphate) (GTPγS). In the reconstituted CHAPS extract, complete and irreversible uncoupling by GTPγS was observed, whereas membrane-bound receptors were uncoupled only partially. Treatment with GTPγS, at concentrations that uncoupled the μ receptors almost completely, resulted in a fourfold decrease in the Bmax of [3H]DAGO binding with a relatively small change in the KD. Competition experiments showed that the Ki of DAGO against [3H]bremazocine was increased 200-fold. This indicates that the observed decrease in Bmax is due to a reduction in affinity of the uncoupled receptors to a level too low to be measurable, whereas the residual coupled receptors retain high affinity for μ agonists. The methods described should prove useful for opioid receptor purification and reconstitution with G proteins and second messenger systems.
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 7
    ISSN: 1520-4804
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 8
    ISSN: 1520-4804
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 9
    ISSN: 1520-4804
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 10
    ISSN: 1520-4804
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...