Publication Date:
2014-12-23
Description:
Purpose To develop a robust and rapid imaging technique for hyperpolarized 13 C MR Spectroscopic Imaging and investigate its performance. Methods A concentric rings readout trajectory with constant angular velocity is proposed for hyperpolarized 13 C spectroscopic imaging and its properties are analyzed. Quantitative analyses of design tradeoffs are presented for several imaging scenarios. The first application of concentric rings on 13 C phantoms and in vivo animal hyperpolarized 13 C MR Spectroscopic Imaging studies were performed to demonstrate the feasibility of the proposed method. Finally, a parallel imaging accelerated concentric rings study is presented. Results The concentric rings MR Spectroscopic Imaging trajectory has the advantages of acquisition timesaving compared to echo-planar spectroscopic imaging. It provides sufficient spectral bandwidth with relatively high efficiency compared to echo-planar spectroscopic imaging and spiral techniques. Phantom and in vivo animal studies showed good image quality with half the scan time and reduced pulsatile flow artifacts compared to echo-planar spectroscopic imaging. Parallel imaging accelerated concentric rings showed advantages over Cartesian sampling in g -factor simulations and demonstrated aliasing-free image quality in a hyperpolarized 13 C in vivo study. Conclusion The concentric rings trajectory is a robust and rapid imaging technique that fits very well with the speed, bandwidth, and resolution requirements of hyperpolarized 13 C MR Spectroscopic Imaging. Magn Reson Med, 2014. © 2014 Wiley Periodicals, Inc.
Print ISSN:
0740-3194
Electronic ISSN:
1522-2594
Topics:
Medicine
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