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  • 1
    Electronic Resource
    Electronic Resource
    Phenotypically immature IgG-bearing B cells in patients with hypogammaglobulinemia (1986)
    Springer
    Journal of clinical immunology 6 (1986), S. 21-25 
    Details
    ISSN: 1573-2592
    Keywords: B Cells ; surface immunoglobulins ; hypogammaglobulinemia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We investigated the prevalence of phenotypically immature IgG B cells (i.e., coexpressing surface IgG and IgM) in the peripheral blood of 12 patients with hypogammaglobulinemia and in normal individuals. Patients had ataxia-telangiectasia (N=1), hyper-IgM combined immunodeficiency (N=1), or common variable immunodeficiency (CVI). IgG/IgM-positive B cells were evaluated by two-color immunofluorescence using fluoresceinor rhodamine-conjugated goat antiserum; to minimize artifacts due toin vivo cytophilic binding of autologous IgG, cell-bound cytophilic Ig were eluted at pH 4 and Fc receptors were blocked by heat-aggregated rabbit IgG before fluorescent staining. All patients, except two with late-onset CVI, had markedly increased proportions of double-stained IgG B cells (56 to 100% of IgG-bearing B cells) in comparison with normal individuals (11 to 33%).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00915360
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    Paper (German National Licenses)
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  • 2
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    The future of Arctic sea-ice biogeochemistry and ice-associated ecosystems (2020)
    In:  EPIC3Nature Climate Change, 10(11), pp. 983-992, ISSN: 1758-678X
    Details
    Publication Date: 2021-07-27
    Description: The Arctic sea-ice-scape is rapidly transforming. Increasing light penetration will initiate earlier seasonal primary production. This earlier growing season may be accompanied by an increase in ice algae and phytoplankton biomass, augmenting the emission of dimethylsulfide and capture of carbon dioxide. Secondary production may also increase on the shelves, although the loss of sea ice exacerbates the demise of sea-ice fauna, endemic fish and megafauna. Sea-ice loss may also deliver more methane to the atmosphere, but warmer ice may release fewer halogens, resulting in fewer ozone depletion events. The net changes in carbon drawdown are still highly uncertain. Despite large uncertainties in these assessments, we expect disruptive changes that warrant intensified long-term observations and modelling efforts.
    Repository Name: EPIC Alfred Wegener Institut
    Type: Article , isiRev
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  • 3
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    BFM-SI: A new implementation of the biogeochemical flux model in sea ice (2010)
    Details
    Publication Date: 2017-04-04
    Description: This work describes a novel implementation of the Biogeochemical Flux Model (BFM) in a sea ice system (BFMSI). The chosen representative groups of the sea ice food web rely on the same dynamics as the BFM. The main differences between BFM and BFMSI stand in the type and number of functional groups, in the parameters assigned to several physiological and ecological processes and in the dimensional size classes they represent. The differential equations of BFMSI are written here according to the nomenclature associated to the new sea ice state variables. At the boundaries, the sea ice system is also coupled to the atmosphere and to the ocean through the exchange of organic and inorganic matter. This is done by computing the entrapment of particulate and dissolved matter and gases when sea ice grows and release to the ocean when sea ice melts to ensure mass conservation. The implementation of the BFM in sea ice and the coupling structure in General Circulation Models will add a new component that may provide new adequate estimate of the role and importance of sea ice biogeochemistry in the global carbon cycle.
    Description: VECTOR, EUR-OCEANS, CMCC
    Description: Published
    Description: 3.7. Dinamica del clima e dell'oceano
    Description: open
    Keywords: sea-ice ; ecosystem ; Baltic ; Greenland ; BFM ; biogeochemical model ; 02. Cryosphere::02.02. Glaciers::02.02.07. Ocean/ice interaction ; 03. Hydrosphere::03.01. General::03.01.07. Physical and biogeochemical interactions ; 03. Hydrosphere::03.04. Chemical and biological::03.04.01. Biogeochemical cycles ; 03. Hydrosphere::03.04. Chemical and biological::03.04.04. Ecosystems
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: report
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  • 4
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    Monitoring a changing Arctic: Recent advancements in the study of sea ice microbial communities (2021)
    In:  EPIC3Ambio, 51(2), pp. 318-332, ISSN: 0044-7447
    Details
    Publication Date: 2022-01-09
    Description: Sea ice continues to decline across many regions of the Arctic, with remaining ice becoming increasingly younger and more dynamic. These changes alter the habitats of microbial life that live within the sea ice, which support healthy functioning of the marine ecosystem and provision of resources for human-consumption, in addition to influencing biogeochemical cycles (e.g. air–sea CO2 exchange). With the susceptibility of sea ice ecosystems to climate change, there is a pressing need to fill knowledge gaps surrounding sea ice habitats and their microbial communities. Of fundamental importance to this goal is the development of new methodologies that permit effective study of them. Based on outcomes from the DiatomARCTIC project, this paper integrates existing knowledge with case studies to provide insight on how to best document sea ice microbial communities, which contributes to the sustainable use and protection of Arctic marine and coastal ecosystems in a time of environmental change.
    Repository Name: EPIC Alfred Wegener Institut
    Type: Article , peerRev , info:eu-repo/semantics/article
    Format: application/pdf
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  • 5
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    Climate change impacts on sea-ice ecosystems and associated ecosystem services (2021)
    In:  EPIC3Elementa: Science of the Anthropocene, 9(1), ISSN: 2325-1026
    Details
    Publication Date: 2022-06-22
    Description: A rigorous synthesis of the sea-ice ecosystem and linked ecosystem services highlights that the sea-ice ecosystem supports all 4 ecosystem service categories, that sea-ice ecosystems meet the criteria for ecologically or biologically significant marine areas, that global emissions driving climate change are directly linked to the demise of sea-ice ecosystems and its ecosystem services, and that the sea-ice ecosystem deserves specific attention in the evaluation of marine protected area planning. The synthesis outlines (1) supporting services, provided in form of habitat, including feeding grounds and nurseries for microbes, meiofauna, fish, birds and mammals (particularly the key species Arctic cod, Boreogadus saida, and Antarctic krill, Euphausia superba, which are tightly linked to the sea-ice ecosystem and transfer carbon from sea-ice primary producers to higher trophic level fish, mammal species and humans); (2) provisioning services through harvesting and medicinal and genetic resources; (3) cultural services through Indigenous and local knowledge systems, cultural identity and spirituality, and via cultural activities, tourism and research; (4) (climate) regulating services through light regulation, the production of biogenic aerosols, halogen oxidation and the release or uptake of greenhouse gases, for example, carbon dioxide. The ongoing changes in the polar regions have strong impacts on sea-ice ecosystems and associated ecosystem services. While the response of sea-ice–associated primary production to environmental change is regionally variable, the effect on iceassociated mammals and birds is predominantly negative, subsequently impacting human harvesting and cultural services in both polar regions. Conservation can help protect some species and functions. However, the key mitigation measure that can slow the transition to a strictly seasonal ice cover in the Arctic Ocean, reduce the overall loss of sea-ice habitats from the ocean, and thus preserve the unique ecosystem services provided by sea ice and their contributions to human well-being is a reduction in carbon emissions.
    Repository Name: EPIC Alfred Wegener Institut
    Type: Article , peerRev
    Format: application/pdf
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