Note: Intro -- Chemistry of Vitamin D Seco-Steroids -- Development of Synthetic Methods for Fluorinated Vitamin D Analogs -- Vitamin D Analogues: Potential Inhibitors of Vitamin D Metabolism -- Synthesis of 26,27-Hexadeutero and Epimeric 26-Trideutero 1,25-Dihydroxycholecalciferols -- Chemical Synthesis of Vitamin D Analogs with Selective Biological Activities -- Chemistry of Vitamin D, its Metabolites and Analogs -- A Practical Synthesis of 1-Alpha-OH Vitamin D3 Analogs -- Synthesis of Biologically Active Cyclopropane Analogues of 1α, 25-Dihydroxy- and 1α-Hydroxy-Vitamin D3 -- Asymmetric Synthesis of 1α, 25-Dihydroxyvitamin D3 and Analogs -- Chemical Synthesis and Studies of 9(11)-Dehydrovitamin D and its 11-Substituted Analogues -- A- and C-Ring Modified Vitamin D Analogues: A Mechanistic Study of the [1,7]-Sigmatropic Hydrogen Shift of the Previtamin D-Vitamin D Equilibrium -- Synthesis and Biologic Evaluation of a Second Generation Photoaffinity Analog of 1,25-Dihydroxyvitamin D3 -- Synthesis of the Unnatural (7Z)-Vitamin D Triene System -- Novel and Stereoselective Syntheses of 1α-Hydroxylated Vitamin D Metabolites -- On Oxidation of the Vitamin D Triene System - A Simple and Convenient Entry into the 19-Nor-10-Oxo-Derivatives of Vitamin D -- Synthesis of 25-Hydroxydihydrotachysterol2 -- Stereochemistry at C(23) of 23,25-Dihydroxy-24-Oxovitamin D3 -- Synthesis and Biological Activity of Highly Active Vitamin D Analogs: General Approaches to the Synthesis of Biologically Potent Vitamin D Sterols -- Syntheses of Labeled Side Chains of Vitamin D Metabolites and Analogs -- Synthesis of 22-Oxa-, and 20-Oxa-Analogues of Vitamin D3 -- Computer Calculations of the Active Conformation of 1,25-Dihydroxy Vitamin D3 -- Vitamin D Metabolism and Catabolism -- Precholecalciferol Formation by an Invertebrate, Psammechinus Miliaris. , Species Variation of Vitamin D Metabolism and Action: Lessons to be Learned from Farm Animals -- Metabolism of Vitamin D in Phagocytic Cells -- Extrarenal Production of Calcitriol in Chronic Renal Failure -- Metabolism of 1,25(OH)2D3 in Perfused Duodena from Normal Chicks -- Intestinal Metabolism of 25-Hydroxyvitamin D3: Effect of the X-Linked Hyp Mutation and 1,25-Dihydroxyvitamin D3 Treatment -- Biosynthesis of Water-Soluble Metabolites of 1,25-Dihydroxyvitamin D3 by Osteosarcoma UMR-106 -- Conversion of 25-Hydroxyvitamin D3 to 19-Nor-10-Oxo-25-Hydroxyvitamin D3 by Solubilized Chick Kidney Mitochondria and Bovine Serum Albumin -- 24-Oxidation of 1,25-(OH)2D3 by a Human Osteosarcoma Cell Line, U-20S -- The Vitamin D Depletion of Chronic Cholestasis is Independent of the Hepatic Metabolism of Vitamin D3 -- Metabolic Clearance Rate and Production Rate of Calcitriol in Uremia. Effects of 25(OH)D Therapy -- Measurement of Production Rate and Metabolic Clearance Rate of 1,25- Dihydroxyvitamin D3 in Conscious Rats Using a Simplified Primed-Infusion Technique -- Metabolism of 1,25(OH)2D3 after Consecutive Dose of 1αOHD3 and 1,25(OH)2D3 in Rats -- 25-Hydroxyvitamin D3 Sulphate in Human Plasma: Observations Using High Performance-Liquid Chromatography and Gas Chromatography-Mass Spectrometry -- The Effect of Vitamin D Status of Vitamin D Metabolism in Chicks -- Identification of a Subset of Dairy Cows that Fail to Produce 1,25-Dihydroxyvitamin D (1,25-(OH)2D) at the Onset of the Hypocalcemia Associated with Parturient Paresis -- The Intact Hepatocyte Hypothesis Applies to the C-25 Hydroxylation of Vitamin D3 in Alcoholic Cirrhosis -- Mechanism of Action of 26,27-Hexafluoro-1,25(OH)2D3 -- 1α, 25(OH)2D3-26,23-Lactone is a Major Metabolite of 1α, 25(OH)2D3 under Physiological Conditions. , 25-Hydroxy-24-Oxovitamin D3 is a Natural Metabolite under Physiological Conditions -- Metabolism of 1,25(OH)2D3 after Single Intravenous or Oral Dose of 1αOHD3 and 1,25(OH)2D3 In Rats -- Administration of Pharmacological Amounts of 25(S), 26-Dihydroxyvitamin D3 Reduces 1,25-Dihydroxyvitamin D3 Synthesis -- The Effect of Growth Hormone on the Phosphate and Calcitriol Responses to Dietary Phosphorus Restriction in Man -- The Effect of Glutethimide on Rapidly Reducing the Circulating Concentration of 1,25-Dihydroxy Vitamin D in Hypervitaminosis D -- Biochemistry and Regulation of Hydroxylases -- Current Models for the Study of the Regulation of 25(OH)D3 Metabolism -- Solubilization and Reconstitution of Mammalian 25-OH-Vitamin D3-24 and 1α-Hydroxylase Activities from Pig Mitochondria -- Molecular Characterization of the Iron-Sulfur Protein from the Porcine Kidney Mitochondrial Hydroxylase System -- Normal Regulation of Calcitriol Production in Gy-Mice: Evidence for Biochemical Heterogeneity in the X-Linked Hypophosphatemic Diseases -- Regulation of 25-Hydroxyvitamin D3 Metabolism in Mitochondria Isolated from Primary Cultures of Chick Kidney Cells: Effects of Parathyroid Hormone and Forskolin -- The Stimulation of 25-Hydroxyvitamin D-1-Hydroxylase by Dietary Phosphorus Restriction Requires Insulin-Like Growth Factor-I (IGF-I) -- Phorbolic Ester Effect on Rat Renal 25-OHD3 1-Hydroxylase Activity: Possible Role of Ca, Phospholipid-Dependent Proteinkinase -- In Vitro Measurement of 25-Hydroxyvitamin D-1-Hydroxylase (1-OHase) Activity in Lactating Mice Using a New, Commercially Available Assay -- Inhibition of Renal Mitochondrial 25(OH)D-1-Hydroxylase Activity by Phosphorylation of Ferredoxin -- Protocol for Partial Purification of the Cytochrome P-450-1α. , Purification of a Cytochrome P-450 from Rabbit Liver Mitochondria Catalyzing 25-Hydroxylation of Vitamin D3 -- Acute Changes in Perfusate Calcium and Phosphorus do not Affect 1-α-Hydroxylase Activity in the Isolated Perfused Rat Kidney -- Does the Administration of Phosphate Increase the Serum 1,25(OH)2D Concentration in X-Linked Hypophosphatemic Rickets? -- Ascorbic Acid Effects on 1-OHase and 24-OHase Activity in Kidney and 1,25(OH)2D3 Receptor Binding in Intestinal Mucosa of Guinea-Pigs -- Metabolism in Vitro of 25-Hydroxyvitamin D3 by Cultured Porcine Alveolar Macrophages -- Evidence that Rat Kidney 25-Hydroxyvitamin D-24-Hydroxylase Can Exist in an Inactive State -- 25 Hydroxyvitamin D, 1α Hydroxylase (1-OH-Lase) Activity in Rhesus Monkeys -- 25-Hydroxylation of Vitamin D3 by a Cytochrome P-450 from Pig Kidney Microsomes -- Receptors for 1,25(OH)2D3 (Biochemistry and Molecular Biology) -- Vitamin D Hormone Receptors: Structure, Regulation and Molecular Function -- Vitamin D3 Receptors: Molecular Structure of the Protein and its Chromosomal Gene -- Definition of the Funktional Domains of the Vitamin D3 Receptor -- Hyperthyroidism Increases Nuclear 1,25-Dihydroxyvitamin D3 Binding in Female Rat Liver -- Changes in Intestinal 1,25-Dihydroxyvitamin D Receptor Durning Aging, Gestation and Pregnancy in Rats -- Positive Cooperativity of the Rat Intestinal 1,25 Dihydroxyvitamin D Receptor -- Ketoconazole Potentiates 1,25-(OH)2D3-Directed Upregulation of 1,25-(OH)2D3-Receptors in Rat Intestine and Bone -- 1α, 25-Dihydroxyvitamin D3 Receptor Defects in Lymphocyte Cell Lines from Vitamin D-Dependent Rickets Type II -- Vitamin K Role in the Interaction of 1,25(OH)2D3 Receptors with DNA -- Administration of 1,25-Dihydroxyvitamin D3 (1,25-(OH)2D3) Upregulates Number of Receptors for 1,25-(OH)2D in Colon Mucosa of Dairy Cows. , Characterization of the Chromosomal Gene of the Mouse Vitamin D Receptor -- Regulation of Vitamin D Action in Rat Osteogenic Sarcoma Cells (UMR-106) -- Duodenum and Colon 1,25-Dihydroxyvitamin D (1,25-(OH)2D) Receptor Concentration is Increased During Lactation in the Rat -- The 1,25-Dihydroxycholecalciferol Level in Plasma does not Influence the Properties of its Intestinal Receptor in Piglets -- The Number of 1,25-Dihydroxyvitamin D Receptors in Rat Intestinal Mucosa have been Markedly Underestimated -- DNA Binding Property of Vitamin D3 Receptors Associated with 26,26,26,27,27,27-Hexafluoro-1,25(OH)2D3 -- Vitamin D3 Binding Protein of Phaseolus Vulgaris Roots. Biochemical and Functional Characterization -- Cell Differentiation / Hematopoiesis / Immunology -- Interaction between the Hematopoietic System and the Vitamin D Endocrine System -- 1,25-(OH)2D3 and Gene Expression During HL-60 Differentiation -- Vitamin D: A Steroid Hormone of the Immune System, by the Immune System, for the Immune System -- Immunoregulatory Properties of 1,25(OH)2D3: Cellular Requirements and Mechanisms -- 1,25-Dihydroxyvitamin D3 and the Regulation of Cancer Cell Replication -- MC 903 - A Novel Vitamin D Analogue with Potent Effects on Cell Proliferation and Cell Differentiation -- 1α, 25-Dihydroxy-22-Oxavitamin D3: A New Synthetic Analogue of Vitamin D3 Having Potent Differentiation-Inducing Activity without Inducing Hypercalcemia in Vivo and in Vitro -- Mechanisms of Cell Fusion Induced by 1α,25-Dihydroxyvitamin D3 -- 1,25(OH)2D3 Promotes Differentiation of Resting Chondrocytes to Hypertrophic Cells in Vitro: A Model System for Evaluating the Potency of Vitamin D Analogs -- 1α,25-Dihydroxyvitamin D3 Synthesis by Synovial Fluid Macrophages in Arthritic Disease -- 1,25-Dihydroxyvitamin-D3 Prolongs Rat Cardiac Allograft Survival. , 1,25-Dihydroxyvitamin D3 as a Synergistic Agent of in Vitro Cyclosporin A-Induced Suppressive Activity in Rheumatoid Arthritis.

Note: Intro -- Acknowledgments -- Contents -- Foreword -- Preface -- Enterohemorrhagic Escherichia coli -- Legionellosis, a Disease Transmitted by Technical Vectors -- Burkholderia/Stenotrophomonas -- Helicobacter pylori -- Biology and Clinical Significance of Chlamydiae -- Borrelia burgdorferi s.l., the Infectious Agent of Lyme Borreliosis -- Streptococcus pyogenes -- Staphylococcus aureus and Staphylococcus epidermidis: Emerging Pathogens in Nosocomial Infections -- Enterococci -- Bordetella pertussis: Increasing Problems with aWell-Known Pathogen and Its Relatives -- Tropheryma whippelii and the (Re)emergence of an Old Disease -- Campylobacter jejuni -- The Changing Image of Mycoplasmas: From Innocent Bystanders to Emerging and Reemerging Pathogens in Human and Animal Diseases -- Gram-Negative Plant Pathogenic Bacteria -- The New Biology and Drug Research -- Author Index -- Subject Index.