Publication Date:
2017-12-19
Description:
A role for 2-Cys peroxiredoxins in facilitating cytosolic protein thiol oxidation A role for 2-Cys peroxiredoxins in facilitating cytosolic protein thiol oxidation, Published online: 18 December 2017; doi:10.1038/nchembio.2536 Cytosolic 2-Cys peroxiredoxins can enable, rather than compete with, rapid thiol oxidation by relaying H2O2-derived oxidizing equivalents to other proteins, suggesting a broadened role for peroxiredoxins as sensors and transmitters of H2O2 signals.
Print ISSN:
1552-4450
Electronic ISSN:
1552-4469
Topics:
Biology
,
Chemistry and Pharmacology
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