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  • 1
    Electronic Resource
    Electronic Resource
    Nucleosomal organization of chromatin in sperm nuclei of the bivalve mollusc Aulacomya ater (1991)
    Springer
    Molecular and cellular biochemistry 101 (1991), S. 93-99 
    Details
    ISSN: 1573-4919
    Keywords: bivalve mollusc ; sperm-specific protein ; chromatin organization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract The sperm nuclei of Aulacomya ater, family Mitylidae, contain three proteins (X, Aa5 and Aa6) which are specific to this cell type coexisting with a set of five somatic-type histones. Information about the chromatin structure resulting from this kind of association is scarce. Therefore, we have probed the structure of this sperm chromatin through digestion with micrococcal nuclease in combination with salt fractionation. The data obtained have allowed us to propose a nucleosomal arrangement for this chromatin. However, two types of nucleosomes would be present in agreement with their protein components.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00229527
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Inflammatory Breast Carcinoma: Pathological or Clinical Entity? (2000)
    Springer
    Breast cancer research and treatment 64 (2000), S. 269-273 
    Details
    ISSN: 1573-7217
    Keywords: inflammatory breast carcinoma ; clinical or pathological diagnosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Inflammatory breast carcinoma (IBC) diagnosis is usually based in the presence of typical clinical symptoms (redness and edema in more than 2/3 of the breast), which are not always associated with pathologic characteristics (subdermal lymphatics involvement). Whether exclusively pathologic findings without clinical symptoms are sufficient for IBC diagnosis remains controversial. A retrospective analysis of 163 clinically diagnosed IBC (CIC) either with dermal lymphatics invasion or not, was compared with another group of 99 patients with dermal lymphatics invasion without clinical symptoms (occult inflammatory carcinoma) (OIC). The following clinical and pathological characteristics have been analyzed and compared: age, menopausal status, clinical axillar node involvement, symptoms duration before diagnosis, grade, estrogen receptors, presence of metastases at diagnosis, local recurrence, metastasic dissemination, disease-free (DFS) and overall survival (OS). Median age was younger in CIC (52.3 vs. 63.8 years; p 〈 0.001). Symptom duration before diagnosis were significantly shorter in CIC (3.4 vs. 6.8 months; p 〈 0.0001). Visceral (36.2% vs. 17.2%; p = 0.001) and brain metastases (7.4% vs. 1%; p = 0.02) was significantly more frequent in CIC. Negative estrogen receptors were more frequent in CIC (34.9% vs. 65.1%; p 〈 0.004). Five-years DFS (25.6 vs. 51.6%; p 〈 0.0001) and OS (28.6 vs. 40%; p 〈 0.05) were shorter in CIC. CIC (regardless of subdermal lymphatics involvement) must be clearly differentiated from OIC. Prognosis of CIC patients is poorer, so this two entities should be clearly differentiated when therepeutic results are reported.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1026512722789
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    Paper (German National Licenses)
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  • 3
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    Physical oceanography (CTD) during URANIA cruise MEDOC-2010_Urania (2017)
    PANGAEA
    Details
    Publication Date: 2023-01-13
    Keywords: CTD/Rosette; CTD-RO; Date/Time of event; DEPTH, water; Event label; Latitude of event; Longitude of event; MEDOC-2010_Urania; MEDOC-2010_Urania-CTD01; MEDOC-2010_Urania-CTD02; MEDOC-2010_Urania-CTD03; MEDOC-2010_Urania-CTD04; MEDOC-2010_Urania-CTD05; MEDOC-2010_Urania-CTD06; MEDOC-2010_Urania-CTD07; MEDOC-2010_Urania-CTD08; MEDOC-2010_Urania-CTD09; MEDOC-2010_Urania-CTD10; MEDOC-2010_Urania-CTD11; MEDOC-2010_Urania-CTD12; MEDOC-2010_Urania-CTD13; MEDOC-2010_Urania-CTD14; MEDOC-2010_Urania-CTD15; MEDOC-2010_Urania-CTD16; MEDOC-2010_Urania-CTD17; MEDOC-2010_Urania-CTD18; MEDOC-2010_Urania-CTD19; MEDOC-2010_Urania-CTD20; MEDOC-2010_Urania-CTD21; MEDOC-2010_Urania-CTD22; MEDOC-2010_Urania-CTD23; MEDOC-2010_Urania-CTD24; MEDOC-2010_Urania-CTD25; MEDOC-2010_Urania-CTD26; MEDOC-2010_Urania-CTD27; MEDOC-2010_Urania-CTD28; MEDOC-2010_Urania-CTD29; MEDOC-2010_Urania-CTD30; MEDOC-2010_Urania-CTD31; MEDOC-2010_Urania-CTD32; MEDOC-2010_Urania-CTD33; MEDOC-2010_Urania-CTD34; MEDOC-2010_Urania-CTD35; MEDOC-2010_Urania-CTD40; MEDOC-2010_Urania-CTD42; MEDOC-2010_Urania-CTD43; MEDOC-2010_Urania-CTD44; MEDOC-2010_Urania-CTD45; MEDOC-2010_Urania-CTD46; MEDOC-2010_Urania-CTD47; MEDOC-2010_Urania-CTD48; MEDOC-2010_Urania-CTD50; Pressure, water; Salinity; Temperature, water; Urania
    Type: Dataset
    Format: text/tab-separated-values, 243198 data points
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    DATA PANGAEA
  • 4
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    Altimetry for the future: Building on 25 years of progress (2021)
    In:  EPIC3Advances in Space Research, ISSN: 02731177
    Details
    Publication Date: 2021-04-14
    Repository Name: EPIC Alfred Wegener Institut
    Type: Article , isiRev
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  • 5
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    Thermal lag correction on Slocum CTD glider data (2011)
    American Meteorological Society
    Details
    Publication Date: 2022-05-25
    Description: Author Posting. © American Meteorological Society, 2011. This article is posted here by permission of American Meteorological Society for personal use, not for redistribution. The definitive version was published in Journal of Atmospheric and Oceanic Technology 28 (2011): 1065–1071, doi:10.1175/JTECH-D-10-05030.1.
    Description: In this work a new methodology is proposed to correct the thermal lag error in data from unpumped CTD sensors installed on Slocum gliders. The advantage of the new approach is twofold: first, it takes into account the variable speed of the glider; and second, it can be applied to CTD profiles from an autonomous platform either with or without a reference cast. The proposed methodology finds values for four correction parameters that minimize the area between two temperature–salinity curves given by two CTD profiles. A field experiment with a Slocum glider and a standard CTD was conducted to test the method. Thermal lag–induced salinity error of about 0.3 psu was found and successfully corrected.
    Description: This work is part of the SINOCOP and GliderBal projects funded by CSIC and Govern Balear, respectively.
    Keywords: Data processingStommel ; In situ observations
    Repository Name: Woods Hole Open Access Server
    Type: Article
    Format: application/pdf
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  • 6
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    Frontal dynamics boost primary production in the summer stratified Mediterranean sea (2017)
    Details
    Publication Date: 2022-05-25
    Description: Author Posting. © The Author(s), 2017. This is the author's version of the work. It is posted here under a nonexclusive, irrevocable, paid-up, worldwide license granted to WHOI. It is made available for personal use, not for redistribution. The definitive version was published in Ocean Dynamics 67 (2017): 767-782, doi:10.1007/s10236-017-1058-z.
    Description: Bio-physical glider measurements from a unique process-oriented experiment in the Eastern Alboran Sea (AlborEx) allowed us to observe the distribution of the deep chlorophyll maximum (DCM) across an intense density front, with a resolution (∼ 400 m) suitable for investigating sub-mesoscale dynamics. This front, at the interface between Atlantic and Mediterranean waters, had a sharp density gradient (Δρ ∼ 1 kg/m3 in ∼ 10 km) and showed imprints of (sub-)mesoscale phenomena on tracer distributions. Specifically, the chlorophyll-a concentration within the DCM showed a disrupted pattern along isopycnal surfaces, with patches bearing a relationship to the stratification (buoyancy frequency) at depths between 30 and 60 m. In order to estimate the primary production (PP) rate within the chlorophyll patches observed at the sub-surface, we applied the Morel and Andrè (J Geophys Res 96:685–698 1991) bio-optical model using the photosynthetic active radiation (PAR) from Argo profiles collected simultaneously with glider data. The highest production was located concurrently with domed isopycnals on the fresh side of the front, suggestive that (sub-)mesoscale upwelling is carrying phytoplankton patches from less to more illuminated levels, with a contemporaneous delivering of nutrients. Integrated estimations of PP (1.3 g C m−2d−1) along the glider path are two to four times larger than the estimations obtained from satellite-based algorithms, i.e., derived from the 8-day composite fields extracted over the glider trip path. Despite the differences in spatial and temporal sampling between instruments, the differences in PP estimations are mainly due to the inability of the satellite to measure DCM patches responsible for the high production. The deepest (depth 〉 60 m) chlorophyll patches are almost unproductive and probably transported passively (subducted) from upper productive layers. Finally, the relationship between primary production and oxygen is also investigated. The logarithm of the primary production in the DCM interior (chlorophyll (Chl) 〉 0.5 mg/m3) shows a linear negative relationship with the apparent oxygen utilization, confirming that high chlorophyll patches are productive. The slope of this relationship is different for Atlantic, mixed interface waters and Mediterranean waters, suggesting the presence of differences in planktonic communities (whether physiological, population, or community level should be object of further investigation) on the different sides of the front. In addition, the ratio of optical backscatter to Chl is high within the intermediate (mixed) waters, which is suggestive of large phytoplankton cells, and lower within the core of the Atlantic and Mediterranean waters. These observations highlight the relevance of fronts in triggering primary production at DCM level and shaping the characteristic patchiness of the pelagic domain. This gains further relevance considering the inadequacy of optical satellite sensors to observe DCM concentrations at such fine scales.
    Description: This work has been partly funded by the Jerico-TNA program, under the project named FRIPP (FRontal Dynamics Influencing Primary Production), and by the Italian Flagship Project RITMARE.
    Keywords: Primary production ; Glider ; Mediterranean sea ; Fronts ; Sub-mesoscale ; AOU
    Repository Name: Woods Hole Open Access Server
    Type: Preprint
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  • 7
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    The AlborEX dataset: Sampling of sub-mesoscale features in the Alboran Aea (2019)
    Copernicus Publications
    Details
    Publication Date: 2022-05-25
    Description: © The Author(s), 2019. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Copernicus Publications 11(1) (2019): 129-145. doi: 10.5194/essd-11-129-2019.
    Description: he AlborEX (Alboran Sea Experiment) consisted of a multi-platform, multi-disciplinary experiment carried out in the Alboran Sea (western Mediterranean Sea) between 25 and 31 May 2014. The observational component of AlborEx aimed to sample the physical and biogeochemical properties of oceanographic features present along an intense frontal zone, with a particular interest in the vertical motions in its vicinity. To this end, the mission included 1 research vessel (66 profiles), 2 underwater gliders (adding up 552 profiles), 3 profiling floats, and 25 surface drifters. Near real-time ADCP velocities were collected nightly and during the CTD sections. All of the profiling floats acquired temperature and conductivity profiles, while the Provor-bio float also measured oxygen and chlorophyll a concentrations, coloured dissolved organic matter, backscattering at 700nm, downwelling irradiance at 380, 410, and 490nm, as well as photo-synthetically active radiation (PAR). In the context of mesoscale and sub-mesoscale interactions, the AlborEX dataset constitutes a particularly valuable source of information to infer mechanisms, evaluate vertical transport, and establish relationships between the thermal and haline structures and the biogeochemical variable evolution, in a region characterised by strong horizontal gradients provoked by the confluence of Atlantic and Mediterranean waters, thanks to its multi-platform, multi-disciplinary nature. The dataset presented in this paper can be used for the validation of high-resolution numerical models or for data assimilation experiment, thanks to the various scales of processes sampled during the cruise. All the data files that make up the dataset are available in the SOCIB data catalog at https://doi.org/10.25704/z5y2-qpye (Pascual et al., 2018). The nutrient concentrations are available at https://repository.socib.es:8643/repository/entry/show?entryid=07ebf505-bd27-4ae5-aa43-c4d1c85dd500 (last access: 24 December 2018).
    Description: We wish to thank the three anonymous reviewers for their constructive comments and the extensive check of the data files. AlborEx was conducted in the framework of PERSEUS EU-funded project (grant agreement no. 287600). Glider operations were partially funded by the JERICO FP7 project. Ananda Pascual acknowledges support from the Spanish National Research Program (E-MOTION/CTM2012-31014 and PRE-SWOT/CTM2016-78607-P). Simon Ruiz and Ananda Pascual are also supported by the Copernicus Marine Environment Monitoring Service (CMEMS) MedSUB project. Antonio Olita was supported by the JERICO-TNA program, through the FRIPP (FRontal Dynamics Influencing Primary Production) project. The profiling floats and some drifters were contributed by the Argo-Italy program. The proceedings of such an ambitious mission would not have been possible without the involvement of numerous staff both at sea and on land: Ana Massanet, Margarita Palmer, Irene Lizaran, Carlos Castilla, Pau Balaguer, Milena Menna, Kristian Sebastián, Sebastián Lora, and Antonio Bussani.
    Repository Name: Woods Hole Open Access Server
    Type: Article
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  • 8
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    Challenges for Sustained Observing and Forecasting Systems in the Mediterranean Sea (2019)
    Details
    Publication Date: 2019-09-19
    Description: The Mediterranean community represented in this paper is the result of more than 30 years of EU and nationally funded coordination, which has led to key contributions in science concepts and operational initiatives. Together with the establishment of operational services, the community has coordinated with universities, research centers, research infrastructures and private companies to implement advanced multi-platform and integrated observing and forecasting systems that facilitate the advancement of operational services, scientific achievements and mission-oriented innovation. Thus, the community can respond to societal challenges and stakeholders needs, developing a variety of fit-for-purpose services such as the Copernicus Marine Service. The combination of state-of-the-art observations and forecasting provides new opportunities for downstream services in response to the needs of the heavily populated Mediterranean coastal areas and to climate change. The challenge over the next decade is to sustain ocean observations within the research community, to monitor the variability at small scales, e.g., the mesoscale/submesoscale, to resolve the sub-basin/seasonal and inter-annual variability in the circulation, and thus establish the decadal variability, understand and correct the model-associated biases and to enhance model-data integration and ensemble forecasting for uncertainty estimation. Better knowledge and understanding of the level of Mediterranean variability will enable a subsequent evaluation of the impacts and mitigation of the effect of human activities and climate change on the biodiversity and the ecosystem, which will support environmental assessments and decisions. Further challenges include extending the science-based added-value products into societal relevant downstream services and engaging with communities to build initiatives that will contribute to the 2030 Agenda and more specifically to SDG14 and the UN's Decade of Ocean Science for sustainable development, by this contributing to bridge the science-policy gap. The Mediterranean observing and forecasting capacity was built on the basis of community best practices in monitoring and modeling, and can serve as a basis for the development of an integrated global ocean observing system.
    Description: Published
    Description: Article 568
    Description: 4A. Oceanografia e clima
    Description: JCR Journal
    Keywords: observing and forecasting systems, sustained observations, ocean variability, FAIR data, climate, operational services, science with and for society, SDG's
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 9
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    CALYPSO 2019 Cruise Report: field campaign in the Mediterranean (2020)
    Woods Hole Oceanographic Institution
    Details
    Publication Date: 2023-03-08
    Description: This cruise aimed to identify transport pathways from the surface into the interior ocean during the late winter in the Alborán sea between the Strait of Gibraltar (5°40’W) and the prime meridian. Theory and previous observations indicated that these pathways likely originated at strong fronts, such as the one that separates salty Mediterranean water and the fresher water in owing from the Atlantic. Our goal was to map such pathways and quantify their transport. Since the outcropping isopycnals at the front extend to the deepest depths during the late winter, we planned the cruise at the end of the Spring, prior to the onset of thermal stratification of the surface mixed layer.
    Description: Funding was provided by the Office of Naval Research under Contract No. N000141613130.
    Repository Name: Woods Hole Open Access Server
    Type: Technical Report
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  • 10
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    Drifter observations reveal intense vertical velocity in a surface ocean front (2023)
    American Geophysical Union
    Details
    Publication Date: 2023-03-11
    Description: © The Author(s), 2022. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Tarry, D., Ruiz, S., Johnston, T., Poulain, P., Özgökmen, T., Centurioni, L., Berta, M., Esposito, G., Farrar, J., Mahadevan, A., & Pascual, A. Drifter observations reveal intense vertical velocity in a surface ocean front. Geophysical Research Letters, 49(18), (2022): e2022GL098969, https://doi.org/10.1029/2022gl098969.
    Description: Measuring vertical motions represent a challenge as they are typically 3–4 orders of magnitude smaller than the horizontal velocities. Here, we show that surface vertical velocities are intensified at submesoscales and are dominated by high frequency variability. We use drifter observations to calculate divergence and vertical velocities in the upper 15 m of the water column at two different horizontal scales. The drifters, deployed at the edge of a mesoscale eddy in the Alboran Sea, show an area of strong convergence (urn:x-wiley:00948276:media:grl64766:grl64766-math-0001(f)) associated with vertical velocities of −100 m day−1. This study shows that a multilayered-drifter array can be an effective tool for estimating vertical velocity near the ocean surface.
    Description: This research was supported by the Office of Naval Research (ONR) Departmental Research Initiative CALYPSO under program officers Terri Paluszkiewicz and Scott Harper. The authors' ONR Grant No. are as follows: DT, SR, AM, and AP N000141613130, TMSJ N000146101612470, PP N000141812418, TO N000141812138, LRC N000141712517, and N00014191269, MB and GE N000141812782 and N000141812039, and JTF N000141812431.
    Keywords: Drifters ; Vertical velocity ; Submesoscale ; Kinematic properties ; Fronts ; Alboran Sea
    Repository Name: Woods Hole Open Access Server
    Type: Article
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