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  • 1
    Electronic Resource
    Electronic Resource
    In situ laser Raman spectra of iron phthalocyanine adsorbed on copper and gold electrodes (1983)
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 87 (1983), S. 3526-3531 
    Details
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/j100241a033
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Production of Heterohybridomas Secreting Autoreactive and Polyreactive Human Monoclonal Antibodies (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of immunology 35 (1992), S. 0 
    Details
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Peripheral blood lymphocytes from two polytransfused renal dialysis patients were transformed by Epstein Barr virus, fused to heteromyeloma and cloned. Eight human monoclonal antibodies from the resulting clones were tested for their binding to variety of antigens by ELISA, indirect immunofluorescence and immunoblotting. Antigens tested included B-cell lines, T and B lymphocytes, red blood cells, chronic lymphocytic leukaemic B cells, IgG, ssDNA, dsDNA. histones, nucleoprotamine, sperm nuclei, thymus and spleen extracts. MOLT4 cell lysatcs, affinity purified autoantigens, tetanus toxoid, bacterial lipopolysaccharide, insulin, and tissue section screen. These human monoclonal antibodies reacted with more than one antigen to varying degrees and were autoreactive and pulyreactive. One of these heterohybridoma cell lines exhibited cytoplasmic staining with an anti-CD5 monoclonal. Our findings support the concept that in adult individuals subset of B cells produce heterogeneous IgM antibodies which can bind to variety of different autoantigens and also to foreign antigens. These monoclonals were different from the autoantibodies usually seen in renal dialysis patients in the sense that they were not lymphocytotoxic.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-3083.1992.tb02831.x
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Arteries of the Hindfoot of the Llama (Lama glama) (2000)
    Oxford, UK : Blackwell Science, Ltd
    Anatomia, histologia, embryologia 29 (2000), S. 0 
    Details
    ISSN: 1439-0264
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The objective of this study was to describe the arterial distribution of the hindfoot of the llama (Lama glama). Ten adult llamas, preserved in 6% formalin solution at 0°C, were dissected. The arterial system was perfused with a solution of 14% coloured plaster; the venous system was perfused with a solution of 17% coloured industrial gelatine. Angiographies were also obtained. In the llama, the arterial distribution is of the saphenous type and this simple sort of irrigation could be used as a didactic model. The caudal branch of the saphenous artery divides into the small lateral plantar artery and the larger medial plantar artery, which continues as the plantar common digital artery III, and it is the main blood supply of the hindfoot. The dorsal pedal artery is underdeveloped and the perforating tarsal artery does not exist in this species. The plantar common digital artery III divides into the plantar proper digital II, III and IV. Branches from the plantar proper digital artery III supply the digits. We compared the arterial distribution of the hindfoot of the llama with that of other domestic animals including the one-humped camel (Camelus dromedarius).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1439-0264.2000.00264.x
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Validation of an HPLC method for the determination of *-dichlorobenzene and naphthalene in mothrepellents (1999)
    Springer
    Accreditation and quality assurance 4 (1999), S. 473-476 
    Details
    ISSN: 1432-0517
    Keywords: Key words Validation ; HPLC ; *-Dichlorobenzene ; Naphthalene ; Mothrepellents.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract  The determination of dichlorobenzene and naphthalene in commercial repellents used in Spain has been validated. This was done using an isocratic regime, to test the reverse -phase HPLC system with acetonitrile: water 65 : 35 (v: v) as the mobile phase, at 20  °C. This technique is proposed for the modular validation of the HPLC system . The results obtained with this method show good agreement with the results provided by the manufacturers of the mothrepellents.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007690050414
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Novel methods for adenovirus-mediated gene transfer to blood vessels in vivo (1997)
    Springer
    Molecular and cellular biochemistry 172 (1997), S. 37-46 
    Details
    ISSN: 1573-4919
    Keywords: gene transfer ; gene expression ; adenovirus ; blood vessel
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract Adenovirus-mediated gene transfer is a promising method for studies of vascular biology and potentially for gene therapy. Intravascular approaches for gene transfer to blood vessels in vivo generally require interruption of blood flow and have several limitations. We have used two alternative approaches for gene transfer to blood vessels in vivo using perivascular application of vectors. First, replication-deficient adenovirus expressing nuclear-targeted bacterial b-galactosidase was injected into cerebrospinal fluid via the cisterna magna of rats. Leptomeningeal cells over the major arteries were efficiently transfected, and adventitial cells of large vessels and smooth muscle cells of small vessels were occasionally stained. When viral suspension was injected with the rat in a lateral position, the reporter gene was expressed extensively on the ipsilateral surface of the brain. Thus, adenovirus injected into cerebrospinal fluid provides gene transfer in vivo to cerebral blood vessels and, with greater efficiency, to perivascular tissue. Furthermore, positioning of the head may ‘target’ specific regions of the brain. Second, vascular gene delivery was accomplished by perivascular injection of virus in peripheral vessels. Injection of the adenoviral vector within the periarterial sheath of monkeys resulted in gene transfer to the vessel wall that was substantial in magnitude although limited to cells in the adventitia. Approximately20% of adventitial cells expressed the transgene, with no gene transfer to cells in the intima or media. These approaches may provide alternative approaches for gene transfer to blood vessels, and may be useful for studies of vascular biology and perhaps vascular gene therapy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1006803202179
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    Paper (German National Licenses)
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  • 6
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    Dipole response of ^{76}Se above 4 MeV (2013)
    American Physical Society (APS)
    Details
    Publication Date: 2013-12-07
    Description: Author(s): P. M. Goddard, N. Cooper, V. Werner, G. Rusev, P. D. Stevenson, A. Rios, C. Bernards, A. Chakraborty, B. P. Crider, J. Glorius, R. S. Ilieva, J. H. Kelley, E. Kwan, E. E. Peters, N. Pietralla, R. Raut, C. Romig, D. Savran, L. Schnorrenberger, M. K. Smith, K. Sonnabend, A. P. Tonchev, W. Tornow, and S. W. Yates The dipole response of 34 76 Se in the energy range from 4 to 9 MeV has been analyzed using a ( γ ⃗, γ ′ ) polarized photon scattering technique, performed at the High Intensity γ -Ray Source facility at Triangle Universities Nuclear Laboratory, to complement previous work performed using unpolarized photon... [Phys. Rev. C 88, 064308] Published Fri Dec 06, 2013
    Keywords: Nuclear Structure
    Print ISSN: 0556-2813
    Electronic ISSN: 1089-490X
    Topics: Physics
    Published by American Physical Society (APS)
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  • 7
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    Geoscientific maps for planning in semi-arid regions: Valencia and Gran Canaria, Spain (1990)
    Elsevier
    Details
    Publication Date: 2022-11-14
    Description: Two case studies of the application of geoscientific maps for planning in semi-arid regions are presented, one for the Mediterranean province of Valencia and another for the island of Gran Canaria (Canaries). Both regions are very dynamic from the point of view of population growth and urban-touristic-industrial development, and they suffer from a serious degree of environmental degradation. The provincial/ island governments have undertaken programmes of geoscientific mapping and assessment to serve as a basis for the establishment of guidelines for future planning. Two map sets have been made (1:200,000 in Valencia and 1:50,000 in Gran Canaria), based on initial maps of homogeneous integrated units. These represent a series of hierarchical land subdivisions, progressively smaller and more detailed (morphodynamic environments, systems, units, elements), defined on the basis of morphostructure, climate, lithology, surficial deposits, landforms, topography, active processes, soils, vegetation and human influence. Each individual map unit is described by means of a form which includes 114 items, summarising its environmental features. Morphodynamic units have been evaluated in terms of qualities significant for planning, and a series of derivative maps has been developed (geologic hazards, soil capability, present degree of erosion, potential erodibility, quality for conservation). A final map shows the most advisable types of uses and the main limitations for human activities, mainly due to engineering geological factors. This is a synthesis document which can be used directly by planners.
    Type: Article , PeerReviewed
    Format: text
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    OceanRep: Article in a Scientific Journal - peer-reviewed
  • 8
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    IL-33 splicing and type 2 inflammation in asthma [Immunology and Inflammation] (2016)
    National Academy of Sciences
    Details
    Publication Date: 2016-08-03
    Description: Type 2 inflammation occurs in a large subgroup of asthmatics, and novel cytokine-directed therapies are being developed to treat this population. In mouse models, interleukin-33 (IL-33) activates lung resident innate lymphoid type 2 cells (ILC2s) to initiate airway type 2 inflammation. In human asthma, which is chronic and difficult to...
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
    Published by National Academy of Sciences
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  • 9
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    Novel Cupriavidus Strains Isolated from Root Nodules of Native Uruguayan Mimosa Species [Plant Microbiology] (2016)
    The American Society for Microbiology (ASM)
    Details
    Publication Date: 2016-05-17
    Description: The large legume genus Mimosa is known to be associated with both alphaproteobacterial and betaproteobacterial symbionts, depending on environment and plant taxonomy, e.g., Brazilian species are preferentially nodulated by Burkholderia , whereas those in Mexico are associated with alphaproteobacterial symbionts. Little is known, however, about the symbiotic preferences of Mimosa spp. at the southern subtropical limits of the genus. In the present study, rhizobia were isolated from field-collected nodules from Mimosa species that are native to a region in southern Uruguay. Phylogenetic analyses of sequences of the 16S rRNA, recA , and gyrB core genome and the nifH and nodA symbiosis-essential loci confirmed that all the isolates belonged to the genus Cupriavidus . However, none were in the well-described symbiotic species C. taiwanensis , but instead they were closely related to other species, such as C. necator , and to species not previously known to be symbiotic (or diazotrophic), such as C. basilensis and C. pinatubonensis . Selection of these novel Cupriavidus symbionts by Uruguayan Mimosa spp. is most likely due to their geographical separation from their Brazilian cousins and to the characteristics of the soils in which they were found. IMPORTANCE With the aim of exploring the diversity of rhizobia associated with native Mimosa species, symbionts were isolated from root nodules on five Mimosa species that are native to a region in southern Uruguay, Sierra del Abra de Zabaleta. In contrast to data obtained in the major centers of diversification of the genus Mimosa , Brazil and Mexico, where it is mainly associated with Burkholderia and Rhizobium / Ensifer , respectively, the present study has shown that all the isolated symbiotic bacteria belonged to the genus Cupriavidus . Interestingly, none of nodules contained bacteria belonging to the well-described symbiotic species C. taiwanensis , but instead they were related to other Cupriavidus species such as C. necator and C. pinatubonensis . These data suggest the existence of a higher diversity within beta-rhizobial Cupriavidus than was previously suspected, and that Mimosa spp. from Sierra del Abra de Zabaleta, may be natural reservoirs for novel rhizobia.
    Print ISSN: 0099-2240
    Electronic ISSN: 1098-5336
    Topics: Biology
    Published by The American Society for Microbiology (ASM)
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  • 10
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    On-chip photonic synapse (2017)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2017-09-28
    Description: The search for new "neuromorphic computing" architectures that mimic the brain’s approach to simultaneous processing and storage of information is intense. Because, in real brains, neuronal synapses outnumber neurons by many orders of magnitude, the realization of hardware devices mimicking the functionality of a synapse is a first and essential step in such a search. We report the development of such a hardware synapse, implemented entirely in the optical domain via a photonic integrated-circuit approach. Using purely optical means brings the benefits of ultrafast operation speed, virtually unlimited bandwidth, and no electrical interconnect power losses. Our synapse uses phase-change materials combined with integrated silicon nitride waveguides. Crucially, we can randomly set the synaptic weight simply by varying the number of optical pulses sent down the waveguide, delivering an incredibly simple yet powerful approach that heralds systems with a continuously variable synaptic plasticity resembling the true analog nature of biological synapses.
    Electronic ISSN: 2375-2548
    Topics: Natural Sciences in General
    Published by American Association for the Advancement of Science (AAAS)
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