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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    European journal of neuroscience 7 (1995), S. 0 
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Patients with ideomotor apraxia (n= 2) or ideational apraxia (n= 2) after left brain stroke and patients with constructional apraxia (n= 2) after cerebrovascular accident of the right hemisphere, as well as 16 non-brain-damaged control subjects, were given a standardized simple motor task: they were asked to make triangular arm movements of specific size, configuration and spatial orientation without visual control. Motion was analysed three-dimensionally in great detail prior to and after kinaesthetic training using a triangular stencil, and 1 day later. The experiment was conceptualized to assess three aspects of motor behaviour: (i) motor planning, operationalized as specification of content parameters of the movement as a whole; (ii) motor programming, the specification of spatiotemporal parameters of movement segments; and (iii) the ability to make use of task-relevant information provided by the training. Patients with ideational apraxia showed signs of impaired motor planning: they had difficulty in selecting the body parts to be moved, and movement concept and configurational aspects were deficient. The kinaesthetic sensorimotor training given seemed not adequate to reduce behavioural deficits. Kinematic peculiarities of patients with ideomotor apraxia can be understood as deficits in programming movement elements. Submovements were more segmented, showed irregularities as well as additional, not-requested elements. Their impairments could be reduced by task-specific sensorimotor training. Patients suffering from visuoconstructive apraxia after right brain damage might have difficulties in making use of new sensorimotor information relevant for spatial-motor aspects, as suggested by training-induced behavioural impairment with a severely constructional apraxic patient.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Chemical Physics Letters 223 (1994), S. 546-552 
    ISSN: 0009-2614
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-2072
    Keywords: Paroxetine ; Selective serotonin reuptake inhibitors ; Depression ; Elderly patients ; Amitriptyline
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Paroxetine is a phenylpiperidine compound which is a selective serotonin reuptake inhibitor (SSRI). Ninety-one hospitalised patients with a major depression (DSM-III) aged 65 and over from six Austrian and one German center were entered into the study, which compared the efficacy and tolerability of paroxetine versus amitriptyline. After 6 weeks both groups showed similarly good therapeutic results. In the paroxetine group, 64.3% of the patients had a 50% or more reduction of the HAMD total score compared to 58.1% in the amitriptyline group. Side effects were distributed similarly in both groups. Patients in the paroxetine group showed a higher incidence of anxiety and agitation; anticholinergic side effects were registered more often in the amitriptyline group.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 36 (1996), S. 249-256 
    ISSN: 1434-6079
    Keywords: 33.20.Kf ; 33.80.Rv ; 35.20.Sd ; 42.62.Fi
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Rotational-vibrational transitions of the triplet system 13Σ g + ← 13Σ u + of the Na2 molecule have been investigated around $$\bar v = 13970 cm^{ - 1} $$ by Doppler-free polarization spectroscopy in a heat pipe and by resonant two-step photoionization in a collimated cold argon beam, seeded with sodium vapor. The fine- and hyperfine structure of the transitions is partly resolved. The analysis of the measured spectra and a theoretical discussion of the expected multiplet structure yields the rotational constantsB′ v (v′=17)=0.0866(4) cm−1 for the upper andB″ v (v″=0)=0.0533(4) cm−1 for the lower state. The difference Δb=b(3Σ u )−b(3Σ g ) of the hyperfine coupling constantsb turns out to be Δb=80 MHz.
    Type of Medium: Electronic Resource
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  • 5
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    Elsevier
    In:  Earth and Planetary Science Letters, 305 (3-4). pp. 445-455.
    Publication Date: 2019-09-23
    Description: Tharsis Tholus, a more than 3.9 Ga old composite shield volcano to the east of the major Tharsis Montes, has experienced a complex history of growth and destruction. On the basis of new high resolution images we analysed the morphology as well as the tectonic structures of the Tharsis Tholus volcano in detail. From morphological data, cross-cutting relations of the surface structures, and crater modelling ages we propose a chronostratigraphy for the volcano-tectonic history of Tharsis Tholus. The strongly faulted volcano reveals two large-scale landslide events followed by two subsequent shield re-growth phases between 3.8 and 1.7 Ga and two caldera collapses. Tharsis Tholus was also affected by regional extensional tectonics between 1.7 Ga and 0.4 Ga recorded by sub-parallel sets of NE trending graben structures. The steep and up to 5.4 km high landslide scarps on Tharsis Tholus suggest deep faulting of the edifice. In order to confirm this hypothesis we used analogue sand box models in which we demonstrated that gravitational flank movement on top of weak basal substrata may have produced the deformation structures as observed on Tharsis Tholus. (C) 2011 Elsevier B.V. All rights reserved.
    Type: Article , PeerReviewed
    Format: text
    Format: text
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  • 6
    Publication Date: 2012-02-23
    Type: Conference or Workshop Item , NonPeerReviewed
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  • 7
    Publication Date: 2012-02-23
    Type: Conference or Workshop Item , NonPeerReviewed
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  • 8
    Publication Date: 2017-07-24
    Description: Small-volume pyroclastic density currents (PDCs) are generated frequently during explosive eruptions with little warning. Assessing their hazard requires a physical understanding of their transport and sedimentation processes which is best achieved by the testing of experimental and numerical models of geophysical mass flows against natural flows and/or deposits. To this end we report on one of the most detailed sedimentological studies ever carried out on a series of pristine small-volume PDC deposits from the 1975 eruption of Ngauruhoe volcano, whose emplacement were also witnessed during eruption. Using high-resolution GPS surveys, a series of lateral excavations across the deposits, and bulk sedimentological analysis we constrained the geomorphology, internal structure and texture of the deposits with respect to laterally varying modes of deposition. Deposition from these PDCs began only on slopes at or around the material's angle of repose (c. 30°). In unconfined settings, the granular PDCs are interpreted to have been quasi-steady, forming sheets and lobes around the angle of repose. Where flows were confined, sheet-like proximal facies made up around 10% of the deposit volume at the angle of repose, but 90% of the material was deposited from apparently unsteady inertial granular PDCs as a distal levée-and-channel facies on slopes well below the repose angle. Hence, confined PDCs were able to travel up to 50% farther than unconfined flows. In the distal facies the deposit width is inversely correlated to the local slope, and the height of the levées (above the deposit centreline) is positively correlated with slope. Internally the deposits comprise three parts, a coarse-grained fines-free sole layer that laterally connects to levées (Zone I), an ashy matrix-supported central body (Zone II) and an overlying coarse plaster of clasts (Zone II). Trends in grain-size data suggests these zones derive from a continuous un-mixing of coarse particles from the initial bulk material by granular segregation that preferentially drives large particles to the upper free surface of the flow where they are concentrated at the front of flow before being deposited and overrun. By comparison to analogue experiments, we suggest a model of flow and deposition where the temporally and spatially varying mode of deposition is determined by the flow velocity, the local slope, the vertical velocity gradient, the velocity gradient at the free surface and the vertical deposition rate. Using this model, estimated vertical deposition rates of c. 5 cm s− 1 from the Ngauruhoe PDCs agree with those determined in laboratory experiments on inertial granular flows.
    Type: Article , PeerReviewed
    Format: text
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  • 9
    Publication Date: 2011-08-06
    Description: We investigate the formation of the outflow channels Dao and Niger Valles near the eastern rim of the Hellas impact basin, Mars. Methods used include image and topography analysis, surface age determination, and finite element modeling. Observations show that deep depressions, source regions for Dao and Niger Valles, are located in an area of shallow subsidence to the south and east of the volcano Hadriaca Patera. Cratering model ages allow for fluvial processes triggered by volcanic loading. Based on the observations, we develop a numerical model of volcanic loading on top of a poroelastic plate leading to flexure and fracturing of the lithosphere. Modeling results show that fracturing may occur up to a depth of about 6 km within an area of shallow subsidence, i.e., the moat surrounding the volcano. Depending on initial aquifer pressurization, groundwater could have reached the surface. Model discharges and channel morphometry suggest that the Dao Vallis channel never reached bankfull flow and that the wetted channel perimeter may have formed during multiple outflow events. The following scenario is proposed: (1) emplacement of a volcanic load on top of a confined, overpressurized aquifer in the early Hesperian, (2) fracturing around the load, possibly reactivated during various stages of volcanic activity, (3) channeling of groundwater to the surface along fractures and outflow channel formation during several events in the Hesperian, and (4) collapse, mass wasting and modification of depressions in the Amazonian.
    Print ISSN: 0148-0227
    Topics: Geosciences , Physics
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  • 10
    Publication Date: 2012-11-27
    Description: Background and Purpose— More than two thirds of all patients after stroke have difficulties with reduced arm function. Electromechanical and robot-assisted arm training devices are used in rehabilitation and might help to improve arm function after stroke. Our systematic review examined the effectiveness of electromechanical and robot-assisted arm training for improving generic activities of daily living, arm function, and arm muscle strength in patients after stroke and also assessed the acceptability and safety of the therapy. Methods— We searched the Cochrane Stroke Group’s Trials Register (last searched July 2011), the Cochrane Central Register of Controlled Trials (CENTRAL; The Cochrane Library 2011, Issue 7), MEDLINE (1950 to July 2011), EMBASE (1980 to July 2011), CINAHL (1982 to July 2011), AMED (1985 to July 2011), SPORTDiscus (1949 to July 2011), PEDro (searched August 2011), COMPENDEX (1972 to July 2011), and INSPEC (1969 to July 2011). We also hand-searched relevant conference proceedings, searched trials and research registers, checked reference lists, and contacted trialists, experts, and researchers in our field as well as manufacturers of commercial devices. Two review authors independently selected trials for inclusion, assessed trial quality, and extracted the data. The primary outcome was activities of daily living; secondary outcomes were impairments such as motor function and motor strength. To minimize bias we included only randomized controlled trials comparing electromechanical and robot-assisted arm training for recovery of arm function with other rehabilitation interventions or no treatment. Results— We included 19 trials (involving 666 participants) in this review. Electromechanical and robot-assisted arm training did improve activities of daily living (standardized mean difference, 0.43, 95% CI, 0.11–0.75; P =0.009; I 2 =67%; Figure ) as well as arm function (standardized mean difference, 0.45; 95% CI, 0.20–0.69; P =0.0004; I 2 =45%), but arm muscle strength did not improve (standardized mean difference, 0.48, 95% CI, –0.06 to 1.03; P =0.08; I 2 =79%). Electromechanical and robot-assisted arm training did not increase the risk of patients to dropout (risk difference, 0.00; 95% CI, –0.04 to 0.04; P =0.82; I 2 =0.0%), and adverse events were rare. Figure. Forest plot of activities of daily living. Conclusions— Patients who receive electromechanical and robot-assisted arm training after stroke are more likely to improve their generic activities of daily living. Paretic arm function may also improve, but not arm muscle strength. However, the results must be interpreted with caution because there were variations between the trials in the duration and amount of training, type of treatment, and in the patient characteristics.
    Keywords: Exercise/exercise testing/rehabilitation, Rehabilitation, Stroke
    Print ISSN: 0039-2499
    Electronic ISSN: 1524-4628
    Topics: Medicine
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