Keywords:
Craniosynostoses
;
Craniosynostoses Treatment
;
Genetics
;
Oral and Maxillofacial Surgery
;
Pediatrics
;
Neurosurgery
;
Pediatric Surgery
;
Aufsatzsammlung
;
Kraniostenose
;
Molekulargenetik
;
Kraniostenose
;
Diagnose
;
Kraniostenose
;
Therapie
;
Kraniostenose
Description / Table of Contents:
Craniosynostosis – the premature fusion of the cranial sutures of an infant’s skull – is a challenging and complex condition that can occur as part of a syndrome or in isolation. In the last two decades increased knowledge about the structure and function of the human genome has enabled the discovery of the molecular etiologies of most forms of syndromic craniosynostosis, which in turn has allowed for the analysis of normal and abnormal sutural biology from the atomic to the population-based level. In parallel with the increase in basic biological understanding, advances in clinical diagnosis and treatment have been achieved including improved prenatal imaging technology and craniofacial surgical techniques as well as condition-specific care in specialized hospitals and clinical units.This book represents a comprehensive overview on the subject of craniosynostosis. Its 19 excellent chapters were written by the foremost authorities in the field for a wide range of readers. They cover topics including a historical review, basic biological and molecular studies, the various common and uncommon syndromes, nonsyndromic craniosynostoses, genetic testing, prenatal ultrasonography, and recent methods of neurosurgical and maxillofacial treatment. Both investigators at the bench and clinicians at the operating table will appreciate this timely book which will be the definitive volume on craniosynostosis for many years to come
Type of Medium:
Online Resource
Pages:
Online-Ressource (X, 250 S)
Edition:
Karger eBooks Collection
ISBN:
9783805595940
,
9783805595957
Series Statement:
Monographs in human genetics 19
URL:
https://karger.com/books/book/2721
URL:
http://dx.doi.org/10.1159/isbn.978-3-8055-9595-7
DDC:
618.92097514
Language:
English
Note:
The definitive volume on craniosynostosis for many years to come
,
Monographs in Human Genetics Vol. 19; Craniosynostoses; Contents; Editorial; Preface; Foreword; Chapter 1; Chapter 2; Chapter 3; Chapter 4; Chapter 5; Chapter 6; Chapter 7; Chapter 8; Chapter 9; Chapter 10; Chapter 11; Chapter 12; Chapter 13; Chapter 14; Chapter 15; Chapter 16; Chapter 17; Chapter 18; Chapter 19; Author Index; Subject Index;
,
Craniosynostosis : a historical overview
,
Uncommon craniosynostosis syndromes : a review of thirteen conditions
,
Discovery of MSX2 mutation in craniosynostosis : a retrospective view
,
Regulation of calvarial bone growth by molecules involved in the craniosynostoses
,
Signal transduction pathways and their impairment in syndromic craniosynostosis
,
The molecular bases for FGF receptor activation in craniosynostosis and dwarfism syndromes
,
Recurrent germline mutations in the FGFR2/3 genes, high mutation frequency, paternal skewing and age-dependence
,
Apert, Crouzon, and Pfeiffer syndromes
,
Muenke syndrome
,
Saethre-Chotzen syndrome : clinical and molecular genetic aspects
,
Craniofrontonasal syndrome : molecular genetics, EFNB1 mutations and the concept of cellular interference
,
Metopic craniosynostosis syndrome due to mutations in GLI3
,
Craniosynostosis and chromosomal alterations
,
Nonsyndromic craniosynostoses
,
Molecular genetic testing of patients with craniosynostosis
,
Prenatal sonographic diagnosis of craniosynostosis
,
Clinical approach to craniosynostosis
,
Imaging studies and neurosurgical treatment
,
Maxillofacial examination and treatment
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