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  • 1
    Keywords: Forschungsbericht
    Type of Medium: Online Resource
    Pages: Online-Ressource (14 S., 304,6 KB) , graph. Darst.
    Series Statement: ITP-UH 03,18
    Language: English
    Note: Auch als Ausdruck vorhanden , Systemvoraussetzungen: Acrobat reader.
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  • 2
    Online Resource
    Online Resource
    Saint Louis :Elsevier Science & Technology,
    Keywords: Inorganic compounds. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (13379 pages)
    Edition: 2nd ed.
    ISBN: 9780080913162
    DDC: 541.2/242
    Language: English
    Note: Cover image -- Title page -- Table of Contents -- Editors-in-Chief -- Volume Editors -- International Advisory Board -- Preface -- Coordination Chemistry: The Past, Present, and Possible Future -- Introduction to Volumes 1 and 2 -- Introduction to Volume 3 -- Introduction to Volume 4 -- Introduction to Volume 5 -- Introduction to Volume 6 -- Introduction to Volume 7 -- Introduction to Volume 8 -- Introduction to Volume 9 -- Permission Acknowledgments -- Volume 1: Fundamentals: Ligands, Complexes, Synthesis, Purification, and Structure -- Section I: Ligands -- 1.1: Bipyridine Ligands -- 1.2: Phenanthroline Ligands -- 1.3: Terpyridine, Oligopyridine, and Polypyridine Ligands -- 1.4: Pyridopyridine Ligands -- 1.5: Heterocyclic and Open-chain 1,2-Diazine Ligands -- 1.6: β-Diketones and Related Ligands -- 1.7: Phenylcyanamide Ligands -- 1.8: Benzimidazole Ligands -- 1.9: Polyatomic Bridging Ligands -- 1.10: Polypyrazolylborate and Scorpionate Ligands -- 1.11: Higher Denticity Ligands -- 1.12: Phosphorus Ligands -- 1.13: Phosphorus Tripodal Ligands -- 1.14: Dichalcogenoimidodiphosph(in)ate Ligands -- 1.15: 1,1-Dithiolato Ligands -- 1.16: Acyclic Arsine, Stibine, and Bismuthine Ligands -- 1.17: Acyclic Thio-, Seleno-, and Telluroether Ligands -- 1.18: Macrocyclic Thio-, Seleno-, and Telluroether Ligands -- 1.19: Acyclic and Macrocyclic Schiff Base Ligands -- 1.20: N Macrocyclic Ligands -- 1.21: Macrocyclic Phosphine and Arsine Ligands -- 1.22: Calixarenes -- 1.23: Porphyrins -- 1.24: Phthalocyanines -- Section II: Synthesis, Purification, and Characterization of Coordination Compounds -- 1.25: Metal Aqua Ions -- 1.26: Solvents and Ionic Liquids -- 1.27: Chromatographic Methods -- 1.28: Crystal Growth Methods -- Section III: Reactions of Coordinated Ligands -- 1.29: Ligand Reactivity: General Introduction. , 1.30: Reactivity and Structure of Complexes of Small Molecules: Carbon Dioxide -- 1.31: Reactivity and Structure of Complexes of Small Molecules: Nitric and Nitrous Oxide -- 1.32: Reactivity and Structure of Complexes of Small Molecules: Dioxygen -- 1.33: Reactivity of Coordinated Oximes -- 1.34: Reactivity of Coordinated Nitriles -- Section IV: Stereochemistry, Structure, and Crystal Engineering -- 1.35: Lone Pair Effects and Stereochemistry -- 1.36: Outer Sphere Coordination Chemistry -- 1.37: Solid State, Crystal Engineering and Hydrogen Bonds -- Section V: New Synthetic Methods -- 1.38: Biphasic Synthesis -- 1.39: Solid State Methods, Hydrothermal -- 1.40: Sol-Gel -- 1.41: Sonochemistry -- 1.42: Microwave Heating -- 1.43: Assemblies and Self-assembly -- 1.44: Electrochemical Methods, Electrocrystallization -- 1.45: Spectroelectrochemistry -- 1.46: Applications of Genetic Engineering -- 1.47: Appendix to Volume 1 -- Volume 2: Fundamentals: Physical Methods, Theoretical Analysis, and Case Studies -- Section I: Physical Methods -- 2.1: Nuclear Magnetic Resonance Spectroscopy -- 2.2: Electron Paramagnetic Resonance Spectroscopy -- 2.3: Electron-Nuclear Double Resonance Spectroscopy and Electron Spin Echo Envelope Modulation Spectroscopy -- 2.4: X-ray Diffraction -- 2.5: Chiral Molecules Spectroscopy -- 2.6: Neutron Diffraction -- 2.7: Time-resolved Infrared Spectroscopy -- 2.8: Raman and FT-Raman Spectroscopy -- 2.9: High-pressure Raman Techniques -- 2.10: Resonance Raman: Coordination Compounds -- 2.11: Resonance Raman: Bioinorganic Applications -- 2.12: Gas Phase Coordination Chemistry -- 2.13: X-ray Absorption Spectroscopy -- 2.14: Photoelectron Spectroscopy -- 2.15: Electrochemistry: General Introduction -- 2.16: Electrochemistry: Proton Coupled Systems -- 2.17: Electrochemistry: Mixed Valence Systems -- 2.18: Electrochemistry: High Pressure. , 2.19: Ligand Electrochemical Parameters and Electrochemical-Optical Relationships -- 2.20: Mössbauer Spectroscopy: Introduction -- 2.21: Mössbauer Spectroscopy: Bioinorganic -- 2.22: Optical (Electronic) Spectroscopy -- 2.23: Stark Spectroscopy -- 2.24: Electronic Emission Spectroscopy -- 2.25: Magnetic Circular Dichroism -- 2.26: Magnetic Circular Dichroism of Paramagnetic Species -- 2.27: Solvatochromism -- 2.28: Mass Spectrometry -- 2.29: Neutralization-Reionization Mass Spectrometry -- 2.30: Electrospray Mass Spectrometry -- 2.31: Magnetism: General Introduction -- 2.32: Electronic Spin Crossover -- 2.33: Excited Spin State Trapping (LIESST, NIESST) -- 2.34: Notes on Time Frames -- Section II: Theoretical Models, Computational Methods, and Simulation -- 2.35: Ligand Field Theory -- 2.36: Angular Overlap Model -- 2.37: Molecular Mechanics -- 2.38: Semiempirical SCF MO Methods, Electronic Spectra, and Configurational Interaction -- 2.39: Density Functional Theory -- 2.40: Time-dependent Density Functional Resonance Theory -- 2.41: Molecular Orbital Theory (SCF Methods and Active Space SCF) -- 2.42: Valence Bond Configuration Interaction Model -- 2.43: Time-dependent Theory of Electronic Spectroscopy -- 2.44: Electronic Coupling Elements and Electron Transfer Theory -- 2.45: Metal-Metal Exchange Coupling -- 2.46: Solvation -- 2.47: Topology: General Theory -- 2.48: Topology: Assemblies -- 2.49: Electrode Potential Calculations -- 2.50: Comparison of DFT, AOM, and Ligand Field Approaches -- 2.51: MO Description of Transition Metal Complexes by DFT and INDO/S -- Section III: Software -- 2.52: AOMX: Angular Overlap Model Computation -- 2.53: GAMESS and MACMOLPLT -- 2.54: CAMMAG -- 2.55: Ligfield -- 2.56: ADF -- 2.57: DeMON -- 2.58: Software for Computational Chemistry -- Section IV: Case Studies. , 2.59: Spectroscopy and Electronic Structure of [FeX4]n− (X=Cl, SR) -- 2.60: Mixed Valence Dinuclear Species -- 2.61: Mixed Valence Clusters -- 2.62: Non-biological Photochemistry Multiemission -- 2.63: Nitrosyl and Oxo Complexes of Molybdenum -- 2.64: Structure of Oxo Metallic Clusters -- 2.65: Centred Zirconium Clusters -- 2.66: Case Study of the Dicyanamidebenzene System -- 2.67: Appendix to Volume 2 -- Volume 3: Coordination Chemistry of the s, p, and f Metals -- 3.1: Group 1s and 2s Metals -- 3.2: Scandium, Yttrium, and the Lanthanides -- 3.3: The Actinides -- 3.4: Aluminum and Gallium -- 3.5: Indium and Thallium -- 3.6: Arsenic, Antimony, and Bismuth -- 3.7: Germanium, Tin, and Lead -- 3.8: Appendix to Volume 3 -- Volume 4: Transition Metal Groups 3-6 -- 4.1: Scandium and Yttrium -- 4.2: Titanium -- 4.3: Zirconium and Hafnium -- 4.4: Vanadium -- 4.5: Niobium and Tantalum -- 4.6: Chromium -- 4.7: Molybdenum -- 4.8: Tungsten -- 4.9: Dinuclear Metal-Metal Bonded Systems -- 4.10: Polyoxo Anions: Synthesis and Structure -- 4.11: Polyoxometalates: Reactivity -- 4.12: Chalcogenide-containing Metal Clusters -- Volume 5: Transition Metal Groups 7 and 8 -- 5.1: Manganese -- 5.2: Technetium -- 5.3: Rhenium -- 5.4: Iron -- 5.5: Ruthenium and Osmium: Low Oxidation States -- 5.6: Ruthenium and Osmium: High Oxidation States -- Volume 6: Transition Metal Groups 9-12 -- 6.1: Cobalt -- 6.2: Iridium -- 6.3: Nickel -- 6.4: Palladium -- 6.5: Platinum -- 6.6: Copper -- 6.7: Silver and Gold -- 6.8: Zinc -- 6.9: Cadmium and Mercury -- 6.10: Appendix to Volume 6 -- Volume 7: From the Molecular to the Nanoscale: Synthesis, Structure, and Properties -- 7.1: High Nuclearity Clusters: Iso and Heteropolyoxoanions and Relatives -- 7.2: High Nuclearity Clusters: Metal-Chalcogenide Polynuclear Complexes. , 7.3: High Nuclearity Clusters: Clusters and Aggregates with Paramagnetic Centers: Oxygen and Nitrogen Bridged Systems -- 7.4: High Nuclearity Clusters: Clusters and Aggregates with Paramagnetic Centers: Cyano and Oxalato bridged Systems -- 7.5: Coordination Polymers: Infinite Systems -- 7.6: Coordination Polymers: Discrete Systems -- 7.7: Supramolecular Systems: Templating -- 7.8: Supramolecular Systems: Self-assembly -- 7.9: Metallomesogens -- 7.10: Sol-Gel Processing of Metal Compounds -- 7.11: Molecular Electron Transfer -- 7.12: Electron Transfer from the Molecular to the Nanoscale -- 7.13: Magnetism from the Molecular to the Nanoscale -- Volume 8: Bio-coordination Chemistry -- 8.1: Recurring Structural Motifs in Bioinorganic Chemistry -- 8.2: Electron Transfer: Cytochromes -- 8.3: Electron Transfer: Iron-Sulfur Clusters -- 8.4: Electron Transfer: Cupredoxins -- 8.5: Alkali and Alkaline Earth Ion Recognition and Transport -- 8.6: Siderophores and Transferrins -- 8.7: Ferritins -- 8.8: Metal Ion Homeostasis -- 8.9: Metallothioneins -- 8.10: Dioxygen-binding Proteins -- 8.11: Heme-peroxidases -- 8.12: Cytochrome P450 -- 8.13: Nonheme Di-iron Enzymes -- 8.14: Non-heme Mono-iron Enzymes -- 8.15: Dicopper Enzymes -- 8.16: Monocopper Oxygenases -- 8.17: Multimetal Oxidases -- 8.18: Molybdenum and Tungsten Enzymes -- 8.19: Superoxide Processing -- 8.20: Oxygen Evolution -- 8.21: Hydrogen Activation -- 8.22: Nitrogen Fixation -- 8.23: Zinc Hydrolases -- 8.24: Dinuclear Hydrolases -- 8.25: Bioorganometallic Chemistry of Cobalt and Nickel -- 8.26: Metal-Radical Arrays -- 8.27: Iron-Sulfur Clusters in Enzyme Catalysis -- 8.28: Denitrification -- 8.29: DNA and RNA as Ligands -- 8.30: Appendix to Volume 8 -- Volume 9: Applications of Coordination Chemistry -- 9.1: Metal Complexes as Catalysts for Polymerization Reactions. , 9.2: Metal Complexes as Hydrogenation Catalysts.
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  • 3
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Physics of Fluids 11 (1999), S. 3401-3415 
    ISSN: 1089-7666
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Vortex formation and merging are investigated in the near field of a driven axisymmetric jet. Acoustic forcing is used to obtain repeatable vortex pairing events, and simultaneous passive scalar and cold-chemistry planar laser-induced flourescence are used to obtain instantaneous images of molecularly mixed jet fluid fraction. The time-varying scalar dissipation field and area-averaged stirredness of the vortex core region are measured at various stages of vortex interaction. These mixing properties are analyzed in conjunction with the observed vortex dynamics, such as the time-dependent vortex convection velocity. The results indicate that there are several phases of the pairing event with distinct mixing characteristics, including vortex roll-up, interaction, coalescence, and reentrainment. Vortex roll-up is nearly laminar with molecular diffusion between the layers of jet and co-flow fluid. The most dramatic change in the mixing state of the leading vortex, which includes the appearance of a uniformly mixed core region, occurs as the trailing vortex approaches and interferes with co-flow fluid entrainment. Vortex coalescence is marked by gross deformation and stretching of the trailing vortex, and rapid homogenization of the diffusion layers. Finally, re-entrainment of pure fluid after the pairing event results in an elongated, nonrotating structure. These stages of vortex pairing correspond to the temporal evolution of vorticity observed in previous studies. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Glutamate-mediated neurotoxicity and a reduced expression of the excitatory amino acid transporter 2 (EAAT2) have been described in the pathogenesis of several acute and chronic neurological conditions. EAAT2 is the major carrier of glutamate in the mammalian brain. However, the principles of EAAT2 expression regulation are not fully understood. For the human brain, extensive alternative splicing of the EAAT2 RNA has been shown. To delineate the complex RNA regulation of EAAT2 we investigated whether the murine species is a suitable model for the study of EAAT2 splicing events. We identified five splice variants (mEAAT2/5UT1–5) encoding different 5′-untranslated sequences and two distinct N-termini of the putative EAAT2 polypeptide. In the murine CNS we found a region-specific expression pattern of the novel 5′-variants of EAAT2 as shown by in situ hybridization, dot blotting and competitive reverse transcription polymerase chain reaction. Furthermore, we performed an expression analysis of the EAAT2 splice variants in the spinal cord of a transgenic model (SOD1G93A) of amyotrophic lateral sclerosis, a motor neurone disease for which altered splicing of EAAT2 has been discussed. We found an increased expression of mEAAT2/5UT4 and a reduction of mEAAT2/5UT5 in the early course of the disease. We conclude that alternative splicing of 5′-sequences may contribute to the regional expression of the EAAT2 RNA and was altered in the pre-symptomatic stage of the SOD1G93A-mouse model for amyotrophic lateral sclerosis.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 143 (2000), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background Despite numerous therapeutic options the treatment of common warts and molluscum contagiosum remains unsatisfactory for both patients and physicians. Imiquimod, a novel topical immune response modifier, has been successfully used for the treatment of external anogenital warts. Objectives We aimed to evaluate the safety, tolerance and efficacy of imiquimod for the treatment of common cutaneous warts and mollusca that were resistant to previous therapeutic interventions. Methods Imiquimod 5% cream was self-applied by the patients to the warts or mollusca once daily for 5 days per week and left in place overnight. Assessment for response and the occurrence of side-effects was performed every 4 weeks until clinical cure or up to a maximum of 16 weeks. Results Twenty-eight of 50 (56%) patients with warts achieved a total clearance (n = 15; 30%) or a 〉 50% reduction in wart size (n = 13; 26%) after a mean treatment period of 9·2 weeks. Twelve of 15 (80%) patients with mollusca achieved a total clearance (n = 8; 53%) or a 〉 50% reduction in molluscum size (n = 4; 27%). There was no difference in response with regard to gender, human immunodeficiency virus serostatus or atopic predisposition. Conclusions Patient-applied 5% imiquimod cream holds promise as an effective treatment of common warts and mollusca in a difficult-to-treat patient population.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 143 (2000), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Stucco keratosis is a skin disorder with papular warty lesions that usually appear on the lower limbs in elderly people. The aetiology, pathogenesis and treatment is still a matter of debate. We report a 75-year-old non-immunosuppressed man with extensive lesions all over his body, which had not responded to curettage or electrodesiccation. To determine the possible role of human papillomavirus (HPV) in stucco keratosis, we used nested polymerase chain reaction (PCR) to identify HPV DNA in the lesions. To include a broad range of both cutaneous and mucosal HPV types, PCR was performed with two sets of degenerate primers. Using this approach we detected HPV types 9, 16, 23b, DL322 and a variant of HPV type 37 in multiple stucco keratoses. Imiquimod (5% cream), a new compound that modifies the immune response by stimulating production of cytokines, applied overnight, three times a week for 5 weeks, resulted in resolution of all treated lesions.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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