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  • 1
    ISSN: 1523-5378
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background. Even after partial gastrectomy, Helicobacter pylori may persist in the residual stomach but be less abundant in the bacterial load. H. pylori stool antigen is a reliable noninvasive tool to detect H. pylori infection in patients without gastrectomy. We thus test whether [1] the course of H. pylori eradication therapy could be diminished [2]; stool antigen can effectively detect H. pylori infection for the patients with gastrectomy.Methods. One hundred and eight patients who had undergone partial gastrectomy were enrolled to receive panendoscopy and provided stool samples for H. pylori stool antigen within 3 days after endoscopy. The H. pylori-infected patients were then randomized to receive either a 3- or 7-day triple therapy for H. pylori eradication. Six weeks later, to evaluate the success of H. pylori eradication, patients received a follow-up endoscopy and again provided stool samples for H. pylori stool antigen.Results. Seventy out of 108 patients, proven to have H. pylori infection, were evenly randomized into 3-day and 7-day therapy groups. The H. pylori eradication rates were similar between the 3-day and 7-day triple therapy (90.9 vs. 93.8%, p 〉 .05). Before therapy, the H. pylori stool antigen was 93% sensitive and 100% specific to detect H. pylori. After therapy, H. pylori stool antigen remain 100% sensitive and 88.3% specific to detect the failure of eradication therapy.Conclusion. H. pylori stool antigen is a highly reliable tool to screen H. pylori infection before therapy and to assess the success of eradication therapy in partial gastrectomy patients. To eradicate H. pylori infection for patients with partial gastrectomy, the duration of triple therapy can be shortened.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    World journal of surgery 19 (1995), S. 424-429 
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé La morbidité, la mortalité et l'efficacité d'une nouvelle technique chirurgicale pour hypertension portale ne comportant pas de shunt portocave mais une section de l'artère splénique, sans splénectomie, une dévascularisation et une transection de l'oesophage (groupe SAD) ont été évaluées. Dix-huit patients cirrhotiques ayant des varices oesophagiennes, opérés selon cette technique, ont été comparés à 54 patients qui ont eu une intervention traditionnelle, toujours sans shunt mais comportant une splénectomie. Les effets immédiats sur la pression portale et la conservation d'une perfusion portale ont été similaires. La durée de l'intervention était plus courte (p〈0.05) et il y a eu moins d'hémorragie globale (p〈0.005) dans le groupe sans splénectomie. Il n'y a eu aucune mortalité et aucune morbidité dans ce groupe de patients. Une mortalité chirurgicale de 2.3% et de 30% a été notée lorsqu'il s'agissait d'une intervention respectivement élective ou urgente dans le groupe splénectomie. Il n'y a eu aucune encéphalopathie dans le groupe SAD, mais il y en a eu une dans le groupe avec splénectomie. A un an, on a constaté une récidive hémorragique chez trois patients dans le groupe splênectomie mais aucune dans le groupe SAD. Ces résultats indiquent que ce procédé modifié est simple et efficace et que le taux de complications est bas.
    Abstract: Resumen En el presente estudio se evaluaron la morbilidad quirúrgica, la mortalidad y la eficacia de la modificación de una operación no derivativa que consiste en la división de la arteria esplénica, en vez de esplenectomía, desvascularización y transección esofágica (grupo SAD). Dieciocho pacientes cirróticos con várices sometidos a este procedimiento fueron comparados con 54 pacientes tratados con una operación no derivativa convencional (grupo esplenectomía). Los resultados demuestran que los efectos inmediatos sobre la presión portal y sobre la preservación de la perfusión portal fueron similares en los dos grupos. El tiempo operatorio fue más corto (P〈0.05) y el volumen de sangrado menor (P〈0.005) en el grupo SAD que en el grupo de la esplenectomía. No se registraron mortaliad ni complicaciones mayores en el grupo SAD. Una mortalildad quirúrgica de 2.3% y de 30% fue registrada en las operaciones electivas y de emergencia, respectivamente, en el grupo esplenectomía. No se observó encefalopatía en el grupo SAD, y ocurrió en un paciente en el grupo esplenectomía. Se presentó sangrado recurrente en 3 pacientes del grupo esplenectomía un año después de la cirugía y en ninguno en el grupo SAD. Estos datos indican que este procedimiento modificado constituye una operación simple y eficaz que se asocia con pocas complicaciones, para el tratamiento de las várices esofágicas.
    Notes: Abstract The surgical morbidity, mortality, and effectiveness of a modified nonshunting operation that includes splenic artery division instead of splenectomy, devascularization, and esophageal transection (SAD group) were evaluated. Eighteen cirrhotic patients with varices who underwent this modified procedure were compared with 54 patients treated with a conventional nonshunting operation (splenectomy group). Results show that immediate effects on portal pressure and preservation of portal perfusion between the two groups were similar. The operative time is shorter (p〈0.05), and the bleeding amount is less (p〈0.005) in the SAD group than in the splenectomy group. No surgical mortality and no major complications were noted in the SAD group. A surgical mortality of 2.3% and 30% was noted for the elective and emergency operations of the splenectomy group, respectively. There was no encephalopathy in the SAD group but one in the splenectomy group. Recurrent bleeding occurred in three patients of the splenectomy group 1 year after surgery but none in the SAD group. These data indicate that this modified procedure is a simple and effective operation with few complications for esophageal varices.
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  • 3
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Incisional hernia is a serious postoperative complication of laparotomy. Selecting an appropriate suture material may lessen such morbidity. This study undertook a prospective, randomized comparison of early-absorbable polyglactin 910 suture versus late-absorbable polydioxanone loop suture for fascial closure after abdominal surgery. A series of 340 consecutive patients undergoing elective laparotomy were randomized to have fascial closure with either polyglactin 910 suture or polydioxanone loop suture between October 1993 and August 1996. A 2-year follow-up revealed that 23 patients had died, and the overall mortality rate was 6.8% (23/340). Ten (10/340, 2.9%) patients, including seven with polyglactin 910 suture and three with polydioxanone loop suture, developed incisional hernias. The early postoperative evaluation revealed an incidence of wound infection of 4.1% (14/340). The development of incisional hernia was not secondary to postoperative wound infection in this study. Among these 340 patients, 192 had malignant diseases and 148 had nonmalignant ones. Fascial closure with polyglactin 910 suture was associated with more incisional hernias than that with polydioxanone loop suture, with marginal significance for patients in the malignant group (4.7% versus 0%, p= 0.07) but not in the nonmalignant group (2.6% versus 4.2%, p= 0.67). In conclusion, abdominal closure with a late-absorbable polydioxanone loop suture may be beneficial to patients with a malignant disease for preventing incisional hernia.
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  • 4
    ISSN: 1573-2568
    Keywords: biliary cancer ; suprahepatic gallbladder ; liver anomaly
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The suprahepatic region is a rare ectopic location of the gallbladder. It usually combines with right lobe anomaly of the liver. Here we report two unusual cases of suprahepatic gallbladder with agenesis or hypogenesis of the right lobe of the liver and biliary cancer. A patient with a gallbladder tumor was admitted to our emergency room with acute cholecystitis and liver abscess. Imaging examinations and operation confirmed the suprahepatic position of gallbladder, agenesis of the right lobe, and dissemination of gallbladder cancer. In the patient with cholangiocarcinoma, CT scans and percutaneous transhepatic cholangiography documented the presence of a hilar tumor and hypogenesis of the right lobe. Both of these patients died from biliary tract cancer soon after operation.
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  • 5
    ISSN: 1573-2568
    Keywords: FIBROBLAST GROWTH FACTOR-1 ; FIBROBLAST GROWTH FACTOR-2 ; HEPATOCELLULAR CARCINOMA ; DIFFERENTIATION ; LIVER ; EXTRACELLULAR MATRIX
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract This study was performed to examine theimmunohistochemical expression of fibroblast growthfactor-1 and fibroblast growth factor-2 in normal liverand a total of 31 cases of hepatocellular carcinoma(HCC). Reactivity for both types of angiogenic factordid not exist in any cellular component of normal liver.For HCC, variable amounts of fibroblast growth factor-1were detected in 6 of 31 cases (19.4%). There was no apparent relationship between theexpression pattern and clinicopathologic factors (P 〉0.1, respectively), except a positive correlation withhistologic grading (P = 0.04). No tumor showedreactivity for fibroblast growth factor-2 in their cancercells. However, both types of peptide could bedemonstrated in the pericellular stroma of HCC. With amean follow-up at 60 months, fibroblast growth factor-1 expression did not correlate with patients'outcome (P 〉 0.1). Our study suggested thatfibroblast growth factor-1 appears to play a certainrole in hepatocarcinogenesis.
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