ISSN:
1432-2013
Keywords:
patch clamp
;
quartz
;
integrating electronics
;
single channels
;
silicone oil
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary We present a method whereby, with integrating electronics, quartz patch electrodes and a novel use of silicone oil, background noise levels as low as .083 pA RMS in a 5 kHz bandwidth (4-pole Butterworth filter) have been achieved in single channel patch clamp recordings. These approaches result in much higher signal to noise ratios for single channel recording than have previously been reported and should allow many investigators to significantly reduce noise at a constant bandwidth or to increase their recording bandwidths by several kHz.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00374642
Permalink
