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  • 1
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    Roosevelt Island Climate Evolution (RICE) ice core isotope record (2017)
    PANGAEA
    In:  Supplement to: Bertler, Nancy A; Conway, Howard; Dahl-Jensen, Dorthe; Emanuelsson, Urban; Winstrup, Mai; Vallelonga, Paul T; Lee, James E; Brook, Edward J; Severinghaus, Jeffrey P; Fudge, Tyler J; Keller, Elizabeth D; Baisden, W Troy; Hindmarsh, Richard C A; Neff, Peter D; Blunier, Thomas; Edwards, Ross L; Mayewski, Paul Andrew; Kipfstuhl, Sepp; Buizert, Christo; Canessa, Silvia; Dadic, Ruzica; Kjær, Helle Astrid; Kurbatov, Andrei; Zhang, Dongqi; Waddington, Edwin D; Baccolo, Giovanni; Beers, Thomas; Brightley, Hannah J; Carter, Lionel; Clemens-Sewall, David; Ciobanu, Viorela G; Delmonte, Barbara; Eling, Lukas; Ellis, Aja A; Ganesh, Shruthi; Golledge, Nicholas R; Haines, Skylar A; Handley, Michael; Hawley, Robert L; Hogan, Chad M; Johnson, Katelyn M; Korotkikh, Elena; Lowry, Daniel P; Mandeno, Darcy; McKay, Robert M; Menking, James A; Naish, Timothy R; Noerling, Caroline; Ollive, Agathe; Orsi, Anais J; Proemse, Bernadette C; Pyne, Alexander R; Pyne, Rebecca L; Renwick, James; Scherer, Reed P; Semper, Stefanie; Simonsen, Marius; Sneed, Sharon B; Steig, Eric J; Tuohy, Andrea; Ulayottil Venugopal, Abhijith; Valero Delgado, Fernando; Venkatesh, Janani; Wang, Feitang; Wang, Shimeng; Winski, Dominic A; Winton, Victoria H L; Whiteford, Arran; Xiao, Cunde; Yang, Jiao; Zhang, Xin (2018): The Ross Sea dipole - temperature, snow accumulation and sea ice variability in the Ross Sea region, Antarctica, over the past 2700 years. Climate of the Past, 14, 193-214, https://doi.org/10.5194/cp-14-193-2018
    Details
    Publication Date: 2024-03-18
    Description: High-resolution, well-dated climate archives provide an opportunity to investigate the dynamic interactions of climate patterns relevant for future projections. Here, we present data from a new, annually-dated ice core record from the eastern Ross Sea. Comparison of the Roosevelt Island Climate Evolution (RICE) ice core records with climate reanalysis data for the 1979-2012 calibration period shows that RICE records reliably capture temperature and snow precipitation variability of the region. RICE is compared with data from West Antarctica (West Antarctic Ice Sheet Divide Ice Core) and the western (Talos Dome) and eastern (Siple Dome) Ross Sea. For most of the past 2,700 years, the eastern Ross Sea was warming with perhaps increased snow accumulation and decreased sea ice extent. However, West Antarctica cooled whereas the western Ross Sea showed no significant temperature trend. From the 17th Century onwards, this relationship changes. All three regions now show signs of warming, with snow accumulation declining in West Antarctica and the eastern Ross Sea, but increasing in the western Ross Sea. Analysis of decadal to centennial-scale climate variability superimposed on the longer term trend reveal that periods characterised by opposing temperature trends between the Eastern and Western Ross Sea have occurred since the 3rd Century but are masked by longer-term trends. This pattern here is referred to as the Ross Sea Dipole, caused by a sensitive response of the region to dynamic interactions of the Southern Annual Mode and tropical forcings.
    Keywords: AGE; Age, maximum/old; Age, minimum/young; DEPTH, ice/snow; ICEDRILL; Ice drill; Isotope ratio mass spectrometry; RICE; Roosevelt Island, Antarctica; δ Deuterium
    Type: Dataset
    Format: text/tab-separated-values, 8136 data points
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    DATA PANGAEA
  • 2
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    The Roosevelt Island Ice Core Chronology 2017 (RICE17) (2019)
    PANGAEA
    Details
    Publication Date: 2024-03-18
    Description: A timescale for the Roosevelt Island Climate Evolution (RICE) ice core, Ross Ice Shelf, West Antarctica, covering the last 83,000 years. Top part (0-343.67m) of the ice chronology is based on annual layer counting. Below 343.67m, the ice chronology is based on gas matching to WAIS Divide on the WD2014 chronology and modelling of delta-age. The gas timescale (entire core) is based on gas matching to target records derived from WAIS Divide on the WD2014 chronology and NGRIP on the GICC05 chronology, modified for continuity with WD2014. The chronology (0-746m) is interpolated between matchpoints assuming piecewise constant accumulation and linearly decreasing annual layer thicknesses. For the top 343.67m, depths of the gas-age matchpoints have been interpolated to the nearest annual layer. Continuity of the RICE ice core ends at 746.00 m, and delta-age was not calculated for the deeper part. In this section, the interpolated gas timescale is calculated using linear interpolation between matchpoints, and ice ages are calculated using a constant delta-age of 200 years. For questions on the use or construction of this chronology, please contact: Mai Winstrup mailto:mai@nbi.ku.dk : Annual-layer-counted ice chronology (0-343.67m) James E. Lee mailto:jlee@coas.oregonstate.edu : Gas chronology (all core), and gas-matched ice chronology (343.67-753.75m)
    Keywords: AGE; Age, standard deviation; DEPTH, sediment/rock; Gas age; Gas age, standard deviation; ice cores; ICEDRILL; Ice drill; rice; RICE; Roosevelt Island; Roosevelt Island, Antarctica; timescale
    Type: Dataset
    Format: text/tab-separated-values, 7649 data points
    Location Call Number Limitation Availability
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    DATA PANGAEA
  • 3
    Electronic Resource
    Electronic Resource
    The Haw River Syndrome: Dentatorubropallidoluysian atrophy (DRPLA) in an African–American family (1994)
    [s.l.] : Nature Publishing Group
    Nature genetics 7 (1994), S. 521-524 
    Details
    ISSN: 1546-1718
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Haw River Syndrome (HRS) is a dominant neurodegenerative disease that has affected five generations of an African–American family in rural North Carolina. The disorder represents a unique spectrum of multiple system degenerations resembling Huntington's disease, spinocerebellar atrophy and ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/ng0894-521
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    Paper (German National Licenses)
    Fulltext
  • 4
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    Response to Comment on “Geochemical Implications of Gas Leakage associated with Geologic CO2 StorageA Qualitative Review” (2013)
    American Chemical Society (ACS)
    Details
    Publication Date: 2013-04-11
    Description: Environmental Science & Technology DOI: 10.1021/es401090n
    Print ISSN: 0013-936X
    Electronic ISSN: 1520-5851
    Topics: Chemistry and Pharmacology , Energy, Environment Protection, Nuclear Power Engineering
    Published by American Chemical Society (ACS)
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    PAPER CURRENT
  • 5
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    Genome-wide localization of small molecules (2014)
    Nature Publishing Group (NPG)
    Details
    Publication Date: 2014-01-10
    Description: Nature Biotechnology 32, 92 (2014). doi:10.1038/nbt.2776 Authors: Lars Anders, Matthew G Guenther, Jun Qi, Zi Peng Fan, Jason J Marineau, Peter B Rahl, Jakob Lovén, Alla A Sigova, William B Smith, Tong Ihn Lee, James E Bradner & Richard A Young A vast number of small-molecule ligands, including therapeutic drugs under development and in clinical use, elicit their effects by binding specific proteins associated with the genome. An ability to map the direct interactions of a chemical entity with chromatin genome-wide could provide important insights into chemical perturbation of cellular function. Here we describe a method that couples ligand-affinity capture and massively parallel DNA sequencing (Chem-seq) to identify the sites bound by small chemical molecules throughout the human genome. We show how Chem-seq can be combined with ChIP-seq to gain unique insights into the interaction of drugs with their target proteins throughout the genome of tumor cells. These methods will be broadly useful to enhance understanding of therapeutic action and to characterize the specificity of chemical entities that interact with DNA or genome-associated proteins.
    Print ISSN: 1087-0156
    Electronic ISSN: 1546-1696
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Published by Nature Publishing Group (NPG)
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    PAPER CURRENT
  • 6
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    Geochemical Implications of Gas Leakage associated with Geologic CO2 StorageA Qualitative Review (2012)
    American Chemical Society (ACS)
    Details
    Publication Date: 2012-11-03
    Description: Environmental Science & Technology DOI: 10.1021/es3029457
    Print ISSN: 0013-936X
    Electronic ISSN: 1520-5851
    Topics: Chemistry and Pharmacology , Energy, Environment Protection, Nuclear Power Engineering
    Published by American Chemical Society (ACS)
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    PAPER CURRENT
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