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  • 1
    Online Resource
    Online Resource
    Projekttitel: Validation of non-invasive body surface mapping using Langendorff-perfused porcine hearts in vitro : Abschlussbericht FKZ 81X2710201 : Laufzeit des Projektes: 01.06.2016-31.03.2017 = (Validierung eines nicht invasiven Verfahrens zur Kartierung der Körperoberfläche an Langendorff-perfundierten Schweineherzen in vitro) (2017)
    Hamburg : Asklepios Klinik St. Georg
    Details Availability
    Keywords: Forschungsbericht ; Bildgebendes Verfahren ; Elektrokardiogramm ; Vorhofflimmern ; Langendorff-Apparat ; Elektrophysiologie ; Schwein
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource (16 Seiten, 3,29 MB) , Illustrationen, Diagramme
    URL: https://doi.org/10.2314/KXP:1676767991
    DOI: 10.2314/KXP:1676767991
    Language: German
    Note: Förderkennzeichen BMBF 81X2710201 , Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource können nicht ausgeschlossen werden
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  • 2
    Electronic Resource
    Electronic Resource
    Total Pulmonary Vein Occlusion as a Consequence of Catheter Ablation for Atrial Fibrillation Mimicking Primary Lung Disease (2003)
    350 Main Street , Malden , MA 02148 , USA , and 9600 Garsington Road , Oxford OX4 2DQ , UK . : Blackwell Science Inc
    Journal of cardiovascular electrophysiology 14 (2003), S. 0 
    Details
    ISSN: 1540-8167
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Introduction: Catheter ablation has recently been used for curative treatment of atrial fibrillation. Methods and Results: Three of 239 patients who underwent ablation close to the pulmonary vein (PV) ostia at our institute developed severe hemoptysis, dyspnea, and pneumonia as early as 1 week and as late as 6 months after the ablation. Because the patients were arrhythmia-free, the treating physician initially attributed the symptoms to new-onset pulmonary disease (e.g., bronchopulmonary neoplasm). After absent PV flow was confirmed by transesophageal echocardiography, transseptal contrast injection depicted a totally occluded PV in all three patients. Successful recanalization, even in chronically occluded Pvs, was performed in all patients. During follow-up, Doppler flow measurements by transesophageal echocardiography demonstrated restenosis in all primarily dilated PV, which led to stent implantation. Conclusion: PV stenosis/occlusion after catheter ablation of atrial fibrillation occurs in a subset of patients. However, because in-stent restenosis occurred in two patients after 6 to 10 weeks, final interventional strategy for PV stenosis or occlusion remains unclear. To prevent future PV stenosis or occlusion, a decrease in target temperature and energy of radiofrequency current or the use of new energy sources (ultrasound, cryothermia, microwave) seems necessary. (J Cardiovasc Electrophysiol, Vol. 14, pp. 366-370, April 2003)
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1540-8167.2003.02334.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Evaluation of Antiarrhythmic Drug Efficacy in Patients with an ICD: (1999)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of cardiovascular electrophysiology 10 (1999), S. 0 
    Details
    ISSN: 1540-8167
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Antiarrhythmic Drug Efficacy in Patients with an ICD. There are a number of novel ways in which implantable cardioverter defibrillator (ICD) endpoints can he used in clinical trials to evaluate antiarrhythmic drugs. The advances in ICD technology (storage, retrieval, and accurate interpretation of ICD electrograms) expand the potential to include the use of an ICD endpoint as a clinical surrogate for sudden death. The ICD also provides the necessary safety net to test new drugs. The frequent need for‘antiarrhythmic drugs in patients already fitted with an ICD (e.g., for atrial fibrillation) necessitates knowledge of the drugs' effect on defibrillator threshold. There are interpretative problems and challenges associated with all types of ICD trials. A particular difficult issue is the degree to which the results of data on antiarrhythmic drug efficacy and safety acquired in the context of an ICD endpoint trial might he extrapolated to patient populations in which the device is not used. These and other challenging issues are discussed, with the goal of enhancing the design and interpretation of clinical trials featuring ICD endpoints.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1540-8167.1999.tb00212.x
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  • 4
    Electronic Resource
    Electronic Resource
    ESCWGA/NASPE/P Experts Consensus Statement: (1999)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of cardiovascular electrophysiology 10 (1999), S. 0 
    Details
    ISSN: 1540-8167
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Anatomic Nomenclature of the AV Junctions. Current nomenclature for the AV junctions derives from a surgically distorted view, placing; the valvar rings and the triangle of Koch in a single plane with anteroposterior and right-left lateral coordinates. Within this convention, the aorta is considered to occupy an anterior position, whereas the mouth of the coronary sinus is shown as being posterior. Although this nomenclature has served its purpose for the description and treatment of arrhythmias dependent on accessory pathways and AV nodal reentry, it is less than satisfactory for the description of atrial and ventricular mapping. To correct these deficiencies, a consensus document has been prepared by experts from the Working Group of Arrhythmias of the European Society of Cardiology and from the North American Society of Pacing and Electrophysiology. It proposes a new, anatomically sound, nomenclature that will be applicable to all chambers of the heart. In this report, we discuss its value for description of the A V junctions and establish the principles of this new nomenclature.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1540-8167.1999.tb00291.x
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  • 5
    Electronic Resource
    Electronic Resource
    Transcatheter Modulation of Atrioventricular Nodal Conduction by Radiofrequency Current (1988)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of interventional cardiology 1 (1988), S. 0 
    Details
    ISSN: 1540-8183
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A new technique is presented in which atrioventricular (A V) nodal conduction properties can be altered in a controlled way through the application of radiofrequency current. In 13 patients with supraventricular arrhythmias (maximal heart rate 215/min) radiofrequency current was delivered to the A V node via a catheter. Nine patients had atrial fibrillation, three had A V nodal reentrant tachycardia, and one patient had accessory pathway mediated A V tachycardia. Radiofrequency current application in these patients increased AV nodal conduction time and antegrade A V nodal effective refractory period significantly. In three patients radiofrequency current had no effect, and the A V node was ablated with direct current shocks. During a mean follow-up period of 10 ± 3 months, all ten patients in whom radiofrequency current application had been successful were asymptomatic without antiarrhythmic medication. No complications were observed, neither during nor after the procedure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1540-8183.1988.tb00948.x
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  • 6
    Electronic Resource
    Electronic Resource
    The Comparison of Balloon versus Rotational Angioplasty (COBRA) Study Protocol: A Prospective Randomized Study (1997)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of interventional cardiology 10 (1997), S. 0 
    Details
    ISSN: 1540-8183
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The Comparison of Balloon versus Rotational Angioplasty (COBRA) study is a prospective, randomized study to compare short- and long-term effects of PTCA and high speed PTCRA (or rotablation) in patients with complex coronary stenoses. Patients with angiographically defined complex coronary stenoses (〉 70% diameter reduction) are included in the study. The trial has recruited 501 patients who will have detailed follow-up for 6 months. The primary end points are: (1) procedural success, defined as angiographically proven residual stenoses 〈 50% and stenosis reduction of ± 20% in absence of new myocardial infarction, emergency CABG, or death; (2) 6-month restenosis in the treated segment; and (3) major cardiac events during the follow-up period. Additionally, improved exercise tolerance will be scored. The final results of the study are expected by late 1997.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1540-8183.1997.tb00041.x
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  • 7
    Electronic Resource
    Electronic Resource
    Risk of Sudden Death After Successful Accessory Atrioventricular Pathway Ablation in Resuscitated Patients with Wolff-Parkinson-White Syndrome (2002)
    Oxford, UK : Blackwell Science Inc
    Journal of cardiovascular electrophysiology 13 (2002), S. 0 
    Details
    ISSN: 1540-8167
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: AP Ablation in Resuscitated WPW Patients. Introduction: Cardiac arrest in patients with Wolff-Parkinson-White (WPW) syndrome can be due to ventricular fibrillation mediated by fast conduction over the accessory pathway during atrial fibrillation. However, if primary ventricular fibrillation is the reason for resuscitation, placement of an implantable cardioverter defibrillator (ICD) would be indicated. The aim of this study was to test the hypothesis that in resuscitated patients with WPW syndrome, recurrences can be prevented by sole ablation of their accessory pathways. Methods and Results: We performed a long-term follow-up study of 48 resuscitated patients with WPW syndrome who underwent successful accessory pathway ablation as their sole primary treatment. Cardiac arrest had occurred either spontaneously in 32 patients (group A) or after intravenous administration of antiarrhythmic drugs in 16 patients (group B) and was never associated with an acute myocardial infarction or other concomitant factors. All patients had normal left ventricular function at echocardiography. A total of 56 accessory AV pathways were ablated successfully with radiofrequency current (n = 55) or during surgery (n = 1) and were located at the left free wall (n = 35), right free wall (n = 8), or septal-paraseptal region (n = 13). Follow-up 5.0 ± 1.9 years after ablation (range 0.2 to 7.9) was obtained in all 48 patients. All of the patients were alive, and none had a life-threatening arrhythmia or syncope after successful ablation of their accessory pathways. Conclusion: In resuscitated patients with WPW syndrome who have normal left ventricular function at echocardiography and no ECG abnormalities suggesting additional electrical disease, ablation of their overt accessory pathways prevented cardiac arrest recurrences; therefore, ICD placement is generally not indicated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1540-8167.2002.00231.x
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  • 8
    Electronic Resource
    Electronic Resource
    Focal Atrial Tachycardia Originating from the Musculature of the Coronary Sinus (2002)
    Oxford, UK : Blackwell Science Inc
    Journal of cardiovascular electrophysiology 13 (2002), S. 0 
    Details
    ISSN: 1540-8167
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Focal Atrial Tachycardia. Focal atrial tachycardias originate predominantly from the right atrium along the crista terminalis and less commonly from the left atrium. Successful catheter ablation usually can be performed via an endocardial approach. We report the case of a 34-year-old patient in whom a focal atrial tachycardia was successfully ablated 4 cm within the coronary sinus after extensive mapping of the left atrial endocardium and coronary sinus using the three-dimensional CARTO mapping system. Rarely, atrial tachycardia can originate from the coronary sinus musculature and require ablation inside the coronary sinus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1540-8167.2002.00068.x
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  • 9
    Electronic Resource
    Electronic Resource
    Prevention of Atrial Fibrillation by Complete Compartmentalization of the Left Atrium Using a Catheter Technique (2000)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of cardiovascular electrophysiology 11 (2000), S. 0 
    Details
    ISSN: 1540-8167
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: LA Compartmentalization for AF Prevention. Introduction: Right atrial compartmentalization has been demonstrated to only reduce the number of atrial fibrillation (AF) episodes: left atrial (LA) fibrillation still occurs. Methods and Results: We report successful LA compartmentalization resulting in isolation of all four pulmonary veins in a 51-year-old woman suffering from paroxysmal AF. Deployment of a complete encircling line resulted in dissociation of electrical activation within the isolated area from the remaining LA. Despite attempts al reinduction by pacing maneuvers inside and outside the isolated area, AF was no longer inducible. During 2l-week follow-up, the patient remained in stable sinus rhythm with rare atrial extrasystoles. Conclusion: If reproducible, this ablation strategy could allow treatment of AF independent of suppression of any triggering event.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1540-8167.2000.tb00032.x
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  • 10
    Electronic Resource
    Electronic Resource
    Radiofrequency Catheter Ablation with the Split-Tip Electrode in the Temperature-Controlled Mode (2001)
    Oxford, UK : Blackwell Futura Publishing, Inc.
    Pacing and clinical electrophysiology 24 (2001), S. 0 
    Details
    ISSN: 1540-8159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: ANTZ, M., et al.: Radiofrequency Catheter Ablation with the Split-Tip Electrode in the Temperature-Controlled Mode. The 7 Fr “split-tip electrode” (2.5-mm tip electrode divided longitudinally into four electrodes with an adjacent 2-mm ring electrode) improves mapping resolution due to its small recording electrodes and narrow interelectrode distances (0.1 mm). The purpose of this study was to examine the temperature-controlled ablation properties of this electrode. In seven anesthetized dogs, the thigh muscles were exposed and superfused with canine blood. A split-tip catheter electrode (with a thermocouple in each of the five electrodes) and a conventional 4-mm catheter electrode were positioned at constant pressure perpendicular or parallel to the surface of the thigh muscle. Impedance measured between each split electrode and a skin patch correlated with the degree of contact with blood and tissue. In the parallel catheter to tissue orientation, split electrodes not in contact with tissue had a low impedance (mean 210–224 Ω), and the split electrode almost entirely in contact with tissue had the highest impedance (380 ± 56 Ω). In the perpendicular catheter to tissue orientation all split electrodes had a similar impedance (mean 279–286 Ω). A total of 75 radiofrequency (RF) lesions were produced in the temperature-controlled mode with the 4-mm electrode (target 60°C) or the split-tip electrode (power limited by the hottest electrode reaching 70°C) with current delivered to all five electrodes simultaneously, or only to electrodes in contact with tissue. Lesion depth was not significantly different between electrodes in the parallel orientation (5.2 ± 0.9 vs 5.1 ± 1.4 vs 5.3 ± 1.1 mm), but significantly deeper with the conventional 4-mm tip electrode in the perpendicular orientation (6.7 ± 1.2 vs 5.3 ± 1.3 vs 5.6 ± 0.9 mm, P 〈 0.05). This was due to higher power delivered to the conventional 4-mm electrode (27 ± 9 vs 17 ± 7 vs 15 ± 7 W, P 〈 0.05) because convective cooling by the blood flow was less effective for the split-tip electrode due to a reduced heat conduction across the interelectrode space from the hottest electrode to cooler areas of the group of five electrodes (mean temperature difference between the hottest split electrodes and the ring electrode: 24°C). Electrode cooling or heat conduction was not effected by the elimination of current delivery to noncontact electrodes. Steam pops occurred in 36% of applications with the conventional 4-mm electrode in the perpendicular orientation but never with the split-tip electrode in spite of the higher target temperature. Measurement of impedance from the split electrodes allow the determination of electrode tissue contact and RF lesions produced with the split-tip electrode in the temperature-controlled mode using a target of 70°C were of reasonable size and not associated with steam pops.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1460-9592.2001.01765.x
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