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  • 1
    Electronic Resource
    Electronic Resource
    The coast and shelf of east and northeast Brazil and material transport (1999)
    Springer
    Geo-marine letters 19 (1999), S. 171-178 
    Details
    ISSN: 1432-1157
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract The east and northeast Brazil shelves of the Southwest Atlantic harbor some unique conditions for tropical passive margins with western boundary currents. The narrow and open shelf is almost entirely covered by carbonate sediments due to little freshwater input and the coast is impacted by the South Equatorial Current (SEC). The wide Abrolhos bank of the east Brazil shelf, presents more diverse conditions, as it forms a physical barrier to the Brazil Current, and upwelling and land input become more significant. The main characteristics of the coast and shelf and findings on biogeochemical, sedimentation, and paleoceanographical processes, addressed by the Joint Oceanographic Projects (JOPS) campaigns, are summarized.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003670050106
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Suspended matter transport in coral reef waters of the Abrolhos Bank, Brazil (1999)
    Springer
    Geo-marine letters 19 (1999), S. 186-195 
    Details
    ISSN: 1432-1157
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract The coral reef system of the Abrolhos Bank, Brazil, is located between 10 and 65 km off the coast. Suspended particulate matter between the coast and the inner arc of the reef was mainly composed of kaolinite clay and reworked fossil carbonate fragments, resuspended from nearshore shoals. Strong permanent and tidal alongshore currents in the nearshore channel together with the geomorphological configuration of the inner arc formed an efficient hydrodynamic and topographic barrier to offshore transport of land-derived material. Most of the material was being transported alongshore. Suspended particulate matter between the inner and outer arcs was dominated by carbonate shells, coral fragments, and needle-shaped biogenic opal, and the reef system was in large part being dominated by the oligotrophic waters of the Brazil Current.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003670050108
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Metabolism of a subtropical Brazilian lagoon (1991)
    Springer
    Biogeochemistry 14 (1991), S. 129-148 
    Details
    ISSN: 1573-515X
    Keywords: coastal lagoon ; autotrophic activity ; heterotrophic activity ; community metabolism ; total CO2 method
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Geosciences
    Notes: Abstract Total community, planktonic and benthic metabolisms were measured by using the carbon dioxide production and consumption, the ‘diurnal curve' method and the in situ bottle incubation technique over an annual cycle in two sublagoons of the Saquarema Lagoon, Brazil. Metabolic rates of the phytoplankton-based lagoon were characterized by considerable daytime and daily variability in production and respiration, by a seasonal shift between net autotrophy and heterotrophy and by an annual balance of production (P = 105 ± 65 mmoles/m2/dayn = 25) and respiration (R = 102 ± 50 mmoles/m2/dayn = 25). Total community metabolism was similar throughout the lagoon, but phytoplankton assimilation rates and benthic respiration showed spatial differences. Bottle incubations compared to total community free water respiration suggested that the pelagic community was 2–5 times more active than the benthos
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00002902
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    Paper (German National Licenses)
    Fulltext
  • 4
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    The pelagic system (1987)
    In:  EPIC3Seawater-sediment interactions in coastal waters. An interdisciplinary approach (J.Rumohr, E.Walger, B.Zeitzschel(eds.), Springer-Verlag,Heidelberg, pp. 32-68
    Details
    Publication Date: 2019-07-17
    Repository Name: EPIC Alfred Wegener Institut
    Type: Article , peerRev
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    PAPER (OA)
  • 5
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    Reporting results from whole-genome and whole-exome sequencing in clinical practice: a proposal for Canada? (2013)
    BMJ Publishing Group
    Details
    Publication Date: 2013-12-19
    Description: Purpose This article proposes recommendations for the use of whole-genome and whole-exome (WGS/WES) sequencing in clinical practice, endorsed by the board of directors of the Canadian College of Medical Geneticists. The publication of statements and recommendations by several international and national organisations on clinical WGS/WES has prompted a need for Canadian-specific guidance. Methods A multi-disciplinary group consisting of lawyers, ethicists, genetic researchers, and clinical geneticists was assembled to review existing guidelines on WGS/WES and identify provisions relevant to the Canadian context. Results Definitions were provided to orient the recommendations and to minimize confusion with other recommendations. Recommendations include the following: WGS/WES should be used in a judicious and cost-efficient manner; WGS/WES should be used to answer a clinical question; and physicians need to explain to adult patients the nature of the results that could arise, so as to allow them to make informed choices over whether to take the test and which results they wish to receive. Recommendations are also provided for WGS/WES in the pediatric context, and for when results implicate patients' family members. Conclusion These recommendations are only a proposal to be developed into comprehensive Canadian-based guidelines. They aim to promote discussion about the reporting of WGS/WES results, and to encourage the ethical implementation of these new technologies in the clinical setting.
    Print ISSN: 0022-2593
    Electronic ISSN: 1468-6244
    Topics: Medicine
    Published by BMJ Publishing Group
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    PAPER CURRENT
  • 6
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    Streamlining ethical review of data intensive research (2016)
    BMJ Publishing Group
    Details
    Publication Date: 2016-08-03
    Description: Research that crosses international borders and analyses large volumes of data from multiple sources is growing. Such data intensive research—for example, precision medicine studies driven by genomic...
    Topics: Medicine
    Published by BMJ Publishing Group
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    PAPER CURRENT
  • 7
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    Streamlining review of research involving humans: Canadian models (2015)
    BMJ Publishing Group
    Details
    Publication Date: 2015-07-25
    Description: Introduction Biomedical research post sequencing of the first human genome is increasingly eroding a traditional ecology of individualist science. It is, furthermore, normalising collective innovation and shared scientific discovery. 1 2 Achieving sound statistical power in a genome-wide association study, for example, can often be well beyond the scope of any one researcher's capacity. For this reason and others, the scientific imperative of research collaboration can be more pronounced in the ‘omics’ disciplines, 3 where millions of data points are needed to make global inferences about links between the human genome and disease. 4 From the scientific necessity to adequately power a study through research collaborations is also born an ethical imperative to do so. That is, the anticipated benefits and harms of a particular study are justified based on the researchers’ sound predictions about potential outcomes and contributions to knowledge. Either underestimating...
    Keywords: Ethics
    Print ISSN: 0022-2593
    Electronic ISSN: 1468-6244
    Topics: Medicine
    Published by BMJ Publishing Group
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    PAPER CURRENT
  • 8
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    Cohort profile of the CARTaGENE study: Quebec's population-based biobank for public health and personalized genomics (2013)
    Oxford University Press
    Details
    Publication Date: 2013-10-25
    Description: The CARTaGENE (CaG) study is both a population-based biobank and the largest ongoing prospective health study of men and women in Quebec. In population-based cohorts, participants are not recruited for a particular disease but represent a random selection among the population, minimizing the need to correct for bias in measured phenotypes. CaG targeted the segment of the population that is most at risk of developing chronic disorders, that is 40–69 years of age, from four metropolitan areas in Quebec. Over 20 000 participants consented to visiting 1 of 12 assessment sites where detailed health and socio-demographic information, physiological measures and biological samples (blood, serum and urine) were captured for a total of 650 variables. Significant correlations of diseases and chronic conditions are observed across these regions, implicating complex interactions, some of which we describe for major chronic conditions. The CaG study is one of the few population-based cohorts in the world where blood is stored not only for DNA and protein based science but also for gene expression analyses, opening the door for multiple systems genomics approaches that identify genetic and environmental factors associated with disease-related quantitative traits. Interested researchers are encouraged to submit project proposals on the study website ( www.cartagene.qc.ca ).
    Print ISSN: 0300-5771
    Electronic ISSN: 1464-3685
    Topics: Medicine
    Published by Oxford University Press
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    PAPER CURRENT
  • 9
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    Can I be sued for that? Liability risk and the disclosure of clinically significant genetic research findings [PERSPECTIVE] (2014)
    Cold Spring Harbor Laboratory Press
    Details
    Publication Date: 2014-05-02
    Description: Genomic researchers increasingly are faced with difficult decisions about whether, under what circumstances, and how to return research results and significant incidental findings to study participants. Many have argued that there is an ethical—maybe even a legal—obligation to disclose significant findings under some circumstances. At the international level, over the last decade there has begun to emerge a clear legal obligation to return significant findings discovered during the course of research. However, there is no explicit legal duty to disclose in the United States. This creates legal uncertainty that may lead to unmanaged variation in practice and poor quality care. This article discusses liability risks associated with the disclosure of significant research findings for investigators in the United States.
    Electronic ISSN: 1549-5469
    Topics: Biology , Medicine
    Published by Cold Spring Harbor Laboratory Press
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  • 10
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    Privacy, Confidentiality, and Health Research. William Lowrance. (2013)
    Oxford University Press
    Details
    Publication Date: 2013-03-19
    Print ISSN: 0300-5771
    Electronic ISSN: 1464-3685
    Topics: Medicine
    Published by Oxford University Press
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    PAPER CURRENT
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