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  • 1
    Online Resource
    Online Resource
    Winnipeg :University of Manitoba Press,
    Keywords: Arctic char-Congresses. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (521 pages)
    Edition: 1st ed.
    ISBN: 9780887550928
    Language: English
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Biology and philosophy 7 (1992), S. 35-60 
    ISSN: 1572-8404
    Keywords: Action principles ; ecosystem structure ; evolution ; information ; natural selection ; non-equilibrium thermodynamics ; teleology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Philosophy
    Notes: Abstract The general attributes of ecosystems are examined and a naturally occurring “reference ecosystem” is established, comparable with the “isolated” system of classical thermodynamics. Such an autonomous system with a stable, periodic input of energy is shown to assume certain structural characteristics that have an identifiable thermodynamic basis. Individual species tend to assume a state of “least dissipation”; this is most clearly evident in the dominant species (the species with the best integration of energy acquisition and conservation). It is concluded that ecosystem structure results from the antagonistic interaction of two nearly equal forces. These forces have their origin in the Principle of Most Action (“least dissipation” or “least entropy production”) and the universal Principle of Least Action. “Most action” is contingent on the equipartitioning of the energy available, through uniform interaction of similar individuals. The trend to “Least action” is contingent on increased dissipation attained through increasing diversity and increasing complexity. These principles exhibit a basic asymmetry. Given the operation of these opposing principles over evolutionary time, it is argued that ecosystems originated in the vicinity of thermodynamic equilibrium through the resonant amplification of reversible fluctuations. On account of the basic asymmetry the system was able to evolve away from thermodynamic equilibrium provided that it remained within the vicinity of “ergodynamic equilibrium” (equilibrium maintained by internal work, where the opposing forces are equal and opposite). At the highest level of generalization there appear to be three principles operating: i) maximum association of free-energy and materials; ii) energy conservation (deceleration of the energy flow) through symmetric interaction and increased homogeneity; and iii) the principle of least action which induces acceleration of the energy flow through asymmetrical interaction. The opposition and asymmetry of the two forces give rise to natural selection and evolution.
    Type of Medium: Electronic Resource
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  • 3
    Publication Date: 2013-03-21
    Description: The EMBO Journal 32, 816 (2013). doi:10.1038/emboj.2013.28 Authors: Alessandra Mancino, Mohamed Habbeddine, Ella Johnson, Lionel Luron, Magali Bebien, Sylvie Memet, Carol Fong, Marc Bajenoff, Xuefeng Wu, Michael Karin, Jorge Caamano, Hongbo Chi, Michael Seed & Toby Lawrence Dendritic cells (DC) are required for priming antigen-specific T cells and acquired immunity to many important human pathogens, including Mycobacteriuim tuberculosis (TB) and influenza. However, inappropriate priming of auto-reactive T cells is linked with autoimmune disease. Understanding the molecular mechanisms that regulate the priming
    Keywords: dendritic cellsI kappa B Kinase alphainterferon regulatory factor 3T-cell priming
    Print ISSN: 0261-4189
    Electronic ISSN: 1460-2075
    Topics: Biology , Medicine
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